一、基本信息
姓名：姜勇
职称：教授
联系邮箱：jiang48231@163.com
二、学习经历
1980.8-1985.7 第一军医大学，临床医学，学士
1987.9-1990.7 第一军医大学，病理生理学，硕士
1994.8-1997.7 北京军事医学科学院，病理生理学，博士
三、拟招收博士后开展的研究方向
1. 炎症的细胞信号转导机制；
2. 脓毒症的分子基础及其治疗策略。
四、主要学术任职
1. 中国病理生理学会休克专业委员会，主任委员；
2. 广东省病理生理学会，副理事长。
五、主要获奖情况
1. 长江学者特聘教授，中华人民共和国教育部，2010；
2. “广东特支计划”百千万工程领军人才，广东省委组织部，2015；
3. 国家重点基础研究发展计划（973计划）项目首席科学家，中华人民共和国科技部，2002
4. 国家杰出青年基金获得者，国家自然科学基金委员会，1999年
六、代表性论文
1. Gong S#, Yan Z#, Liu Z#, Niu M#, Fang H, Li N, Huang C, Li L, Chen G, Luo H, Chen X, Zhou H, Hu J, Yang W, Huang Q, Schnabl B, Chang P*, Billiar TR, Jiang Y*, Chen P*. Intestinal microbiota mediates the susceptibility to polymicrobial sepsis-induced liver injury by granisetron generation in mice. Hepatology 2019; 69(4):1751-1767.
2. Gong S#, Lan T#, Zeng L, Luo H, Yang X, Li N, Chen X, Liu Z, Li R, Win S, Liu S, Zhou H, Schnabl B, Jiang Y*, Kaplowitz N, Chen P*. Gut microbiota mediates diurnal variation of acetaminophen induced acute liver injury in mice. J Hepatol 2018; 69(1):51-59.
3. Gao K, Huang C, Li J, Luo H, Li L, Huang Y, Jin J, Jiang Y*. Exosomes derived from septic mouse serum modulate immune responses via exosome-associated cytokines. Front Immunol. 2019 Jul 12;10:1560
4. Jia L#, Zhao J#, Yang C, Liang Y, Long P, Liu X, Qiu S, Wang L, Xie J, Li H, Liu H, Guo W, Wang S, LI P, Zhu B, Hao R , Ma H*, Jiang Y*, Song H*. Severe pneumonia caused by coinfection with influenza virus followed by methicillin-resistant staphylococcus aureus induces higher mortality in mice. Front Immunol 2019; 9:3189.
5. Li Z, Scott MJ, Fan EK, Li Y, Liu J, Xiao G, Li S, Billiar TR, Wilson MA, Jiang Y*, Fan J*. Tissue damage negatively regulates LPS-induced macrophage necroptosis. Cell Death Differ 2016; 23(9): 1428-47.
6. Wang J, Vodovotz Y, Fan L, Yuehua Li, Liu Z, Namas R, Barclay D, Zamora R, Billiar TR, Wilson M, Fan J*, Jiang Y*. The injury-induced MRP8/MRP14 stimulates IP-10/CXCL10 in monocytes/macrophages. FASEB J 2015; 29(1): 250-62.
7. Xu J, Jiang Y*, Wang J, Shi X, Liu Q, Liu Z, Li Y, Scott MJ, Xiao G, Li S, Fan L, Billiar TR, Wilson MA, Fan J*. Macrophage endocytosis of high mobility group box 1 (HMGB1) triggers pyroptosis. Cell Death Differ 2014; 21(8): 1229-1239.
8. Yang M, Liu C, Niu M, Hu Y, Guo M, Zhang J, Luo Y, Yuan W, Yang M, Yun M, Guo L, Yan J, Liu D, Liu J, Jiang Y*. Phage-display library biopanning and bioinformatic analysis yielded a high-affinity peptide to inflamed vascular endothelium both in vitro and in vivo. J Control Release 2014; 174: 72–80.
9. Liu W, Deng J, Xu J, Wang H, Yuan M, Liu N, Jiang Y*, Liu J*. High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins. J Mol Cell Cardiol 2010; 49(3): 438-48.
10. Gong X, An Z, Wang Y, Guan L, Fang W, Strömblad S, Jiang Y*, Zhang H*. Kindlin-2 controls sensitivity of prostate cancer cells to cisplatin-induced cell death. Cancer Lett 2010; 299: 54-62.
11. Xing F*, Liu J, Mo Y, Liu Z, Qin Q, Wang J, Fan Z, Long Y, Liu N, Zhao K* and Jiang Y*. Lysophosphatidylcholine up-regulates human endothelial nitric oxide synthase gene transactivity by c-Jun N-terminal kinase signaling pathway. J Cell Mol Med 2009; 13 (6): 1136-1148.
12. Wang H, Xu Q, Xiao F, Jiang Y*, Wu Z*. Involvement of the p38 mitogen-activated protein kinase α, β, and γ isoforms in myogenic differentiation. Mol Biol Cell 2008; 19: 1519-1528.
13. Xu J, Zhong S, Liu J, Li L, Li Y, Wu X, Li Z, Deng P, Zhang J, Zhong N, Ding Y, Jiang Y*. Detection of severe acute respiratory syndrome coronavirus in brain: potential role of the chemokine Mig in pathogenesis. Clin Infect Dis 2005; 41 (8): 1089-1096.
14. Jiang Y*, Xu J, Zhou C, Wu Z, Zhong S, Liu J, Luo W, Chen T, Qin Q, Deng P. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med 2005; 171 (8): 850-857.
15. New L#, Jiang Y#, Zhao M, Liu K, Flood LJ, Kato Y, Parry GCN, Han J*. PRAK, A novel protein kinase regulated by the p38 MAP kinase. EMBO J 1998; 17(12): 3372-3384. (#Co-first author)
16. Huang S, Jiang Y, Li Z, Nishda E, Mathias P, Lin S, Ulevitch RJ, Nemerow GR, Han J*. Apoptosis signaling pathway in T cells is composed of ICE/Ced-3 family protease and MAP kinase 6b. Immunity 1997; 6(6): 739-749.
17. Han J*, Jiang Y, Li Z, Kravchenko VV, Ulevitch RJ. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 1997; 386(20): 296-299.
