一、基本信息
姓名：黄巧冰
职称：教授
联系邮箱：bing@smu.edu.cn
二、学习经历
1980.8-1985.7 第一军医大学，军医专业，学士
1987.9-1990.7 第一军医大学，病理生理学专业，硕士
1994.9-1997.7 军事医学科学院，病理生理学专业，博士
1995.12-1997.5 美国Texas A&M大学，联合培养博士生
2002.12-2003.5 美国Texas A&M大学，高级访问学者
三、拟招收博士后开展的研究方向
1. 内皮细胞功能调节在疾病发生中的作用
2. 糖尿病微血管并发症的发生机制
3. 重症休克发生的微循环机制
四、主要学术任职
1. 中国微循环学会，第五届副理事长；
2. 中国病理生理学会休克专业委员会，副主任委员；
3. 广东省病理生理学会学会，常务理事，监事长；
4. 中国微循环学会糖尿病微循环专业委员会，副主任委员。
五、主要获奖情况
1. 广东省“特支计划”教学名师，广东省人才工作领导小组办公室，2018.04
2. 广东省高校教学名师，广东省教育厅，2017.06
3. 广东省师德先进个人，广东省教科文卫工会，广东省教育厅办公室，2015.07
4. 南粤优秀教师，中共广东省教育工作委员会，省教育厅，省人社厅，省总工会，2015.09
六、代表性论文 （近四年，通讯和共同通讯作者）
1. Chen L, Zhou T, Wu N, O'Brien A, Venter J, Ceci L, Kyritsi K, Onori , Gaudio E, Sybenga A, Xie L, Wu C, Fabris L, Invernizzi P, Zawieja D, Liangpunsakul S, Meng F, Francis H, Alpini G*, Huang Q*, Glaser S*. Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1525-1539.
2. Weng J, Yu L, Chen Z, Su H, Yu S, Zhang Y, Lei X, Chen L, Cui Y,Huang Q*, Jiang Y*, Guo X*. β-catenin phosphorylation at Y654 and Y142 is crucial for high mobility group box-1 protein-induced pulmonary vascular hyperpermeability. J Mol Cell Cardiol. 2018 Dec 25;127:174-184.
3. Wang W, Weng J, Yu L,Huang Q*, Jiang Y*, Guo X*. Role of TLR4-p38 MAPKHsp27 signal pathway in LPS-induced pulmonary epithelial hyperpermeability. BMC Pulm Med. 2018 Nov 27;18(1):178.
4. Li P, Chen D, Cui Y, Zhang W, Weng J, Yu L, Chen L, Chen Z, Su H, Yu S, Wu J, Huang Q*, Guo X*. Src Plays an Important Role in AGE-Induced Endothelial Cell Proliferation, Migration, and Tubulogenesis. Front Physiol. 2018 Jun 21;9:765. eCollection 2018.
5. Cheng A, Lu Y, Huang Q*, Zuo Z*. Attenuating oxygen-glucose deprivation-caused autophagosome accumulation may be involved in sevoflurane postconditioning-induced protection in human neuron-like cells. Eur J Pharmacol. 2019 Jan 30;849:84-95.
6. Wu J, Zhang W, Liu X, Wu L, He G, Li P, Guo X, Chen Z,Huang Q*. Apocynin protects endothelial cells from endoplasmic reticulum stress-induced apoptosis via IRE1-α engagement. Mol Cell Biochem. 2018 Dec; 449(1-2): 257-265.
7. Zhou X, Weng J, Xu J, Xu Q, Wang W, Zhang W, Huang Q*, Guo X*. mDia1 is Crucial for Advanced Glycation End Product-Induced Endothelial Hyperpermeability. Cell Physiol Biochem. 2018;45(4):1717-1730.
8. Xiao Y, Wu J, Yuan Y, Guo X, Chen B, Huang Q*. Effect of moesin phosphorylation on high‑dose sphingosine‑1‑phosphate‑induced endothelial responses. Mol Med Rep. 2018(17): 1933-1939.
9. Wan Y, Meng F, Wu N, Zhou T, Venter J, Francis H, Kennedy L, Glaser T, Bernuzzi F, Invernizzi P, Glaser S, Huang Q*, Alpinin G*. Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells. Hepatology. 2017 Aug;66(2):528-541.
10. Zhang WJ, Zhang YY, Guo XH, Zeng ZH, WuJ , Liu YA, He J, Wang RT, Huang QB*, Chen ZQ*. Sirt1 protects endothelial cells against LPS-induced barrier dysfunction. Oxid Med Cell Longev. 2017;2017:4082102. doi: 10.1155/2017/4082102. Epub 2017 Oct 25.
11. Xiao Y, Wu J, Yuan Y, Guo X, Chen B, Huang Q*. Effect of moesin phosphorylation on high‑dose sphingosine‑1‑phosphate‑induced endothelial responses. Mol Med Rep. 2017 Nov 13. doi: 10.3892/mmr.2017.8029. 2018(17): 1933-1939.
12. Wang L, Wu J, Guo X, Huang X, Huang Q*. RAGE Plays a Role in LPS-Induced NF-κB Activation and Endothelial Hyperpermeability. Sensors (Basel). 2017; 7(4): pii: E722. doi: 10.3390/s17040722
13. Zhang SS, Wu Z, Zhang Z, Xiong ZY, Chen H, Huang QB*. Glucagon-like peptide-1 inhibits the receptor for advanced glycation endproducts to prevent podocyte apoptosis induced by advanced oxidative protein products. Biochem Biophys Res Commun. 2017, Jan 12,482:1413-1419.
14. Jin H, Li Z, Guo X, Tong H, Liu Z, Chen Y, Su L*, Huang Q*. Microcirculatory Disorders and Protective Role of Anti-oxidant in Severe Heat Stroke: A Rat Study. Shock. 2016 Dec; 6(6):688-695.
15. Wang Q, Fan A, Yuan Y, Chen L, Guo X, Huang X, Huang Q*. Role of Moesin in Advanced Glycation End Products-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells. Sci Rep. 2016 Mar 9; 6:22749.
16. Fan A, Wang Q, Yuan Y, Cheng J, Chen L, Guo X, Li Q, Chen B, Huang X, Huang Q*. Liver X receptor-α and miR-130a-3p regulate expression of sphingosine 1-phosphate receptor 2 in human umbilical vein endothelial cells. Am J Physiol Cell Physiol. 2016 Feb 1;310(3):C216-26.
