一、基本信息
姓名:段晓品
职称:教授
联系邮箱:dxpwww654@i.smu.edu.cn
二、学习经历
2004.9-2008.7 河北大学,药学专业,学士
2008.9-2010.7 沈阳药科大学,药剂学专业,硕士
2010.9-2013.7 沈阳药科大学与上海药物研究所联合培养,药剂学专业,博士
2014.1-2018.8 芝加哥大学,博士后
三、拟招收博士后开展的研究方向
1. 新型纳米制剂用于肿瘤免疫治疗;
2. 新型纳米制剂用于体内细胞示踪。
四、主要学术任职
1. 中国抗癌协会纳米肿瘤学专业委员会,委员
五、主要获奖情况
1. ACS-Yao Yuan Award of Medicinal Chemistry, First Place,2017;
2. 中国药学会科技奖一等奖,2015
六、代表性论文
1. Xiaopin Duan#, Christina Chan#, Wenbo Han#, Nining Guo, Ralph R Weichselbaum, Wenbin Lin*, Immunostimulatory nanomedicines synergize with checkpoint blockade immunotherapy to eradicate colorectal tumors. Nat Commun. 2019, 10: 1899 (IF: 11.878, 中科院JCR分区小类:2区)
2. Xiaopin Duan#, Christina Chan#, Wenbin Lin*, Nanoparticle-mediated immunogenic cell death enables and potentiates cancer immunotherapy. Angew. Chem. Int. Ed. 2019, 58: 670-680 (IF: 12.257, 中科院JCR分区小类:2区)
3. Xiaopin Duan, Christina Chan, Nining Guo, Wenbo Han, Ralph R Weichselbaum, Wenbin Lin*, Photodynamic therapy mediated by nontoxic core-shell nanoparticles synergize with immune checkpoint blockade to elicit antitumor immunity and antimetastatic effect on breast cancer. J. Am. Chem. Soc. 2016, 138: 16686-16695 (IF: 14.695, 中科院JCR分区小类:1区)
4. Chunbai He#, Xiaopin Duan#, Nining Guo#, Christina Chan, Christopher Poon, Ralph R Weichselbaum, Wenbin Lin*, Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy. Nat. Commun. 2016, 7: 12499 (IF: 11.878, 中科院JCR分区小类:1区)
5. Xiaopin Duan#, Jisheng Xiao#, Qi Yin, Zhiwen Zhang, Haijun Yu, Shirui Mao, Yaping Li*, Smart pH-sensitive and temporal-controlled polymeric micelles for effective combination therapy of doxorubicin and disulfiram. ACS Nano 2013, 7: 5858-5869 (IF: 13.903, 中科院JCR分区小类:1区).
6. Xiaopin Duan, Demin Liu, Christina Chan, Wenbin Lin*, Polymeric Micelle-Mediated Delivery of DNA-Targeting Organometallic Complexes for Resistant Ovarian Cancer Treatment. Small 2015, 11: 3962-3972 (IF: 10.856, 中科院JCR分区小类:1区).
7. Xiaopin Duan, Yaping Li, Physicochemical characteristics of nanoparticles affect circulation, biodistribution, cellular internalization, and trafficking. Small 2013, 9: 1521-1532 (IF: 10.856, 中科院JCR分区小类:1区).
8. Zhi-Ming Zhang#, Xiaopin Duan#, Shuang Yao, Zhishu Wang, Zekai Lin, Yang-Guang Li, La-Sheng Long, En-Bo Wang*, Wenbin Lin*, Cation-mediated optical resolution and anticancer activity of chiral polyoxometalates built from entirely achiral building blocks. Chem. Sci. 2016, 7: 4220-4229 (IF: 9.556, 中科院JCR分区小类:2区)
9. Xiaopin Duan, Chunbai He, Steven J. Kron, Wenbin Lin*, Nanoparticle formulations of cisplatin for cancer therapy. WIRES Nanomed. Nanobi. 2016, 8: 776-791 (IF: 6.140, 中科院JCR分区小类:3区)
10. Christopher Poon#, Xiaopin Duan#, Christina Chan, Wenbo Han, Wenbin Lin*, Nanoscale coordination polymers codeliver carboplatin and gemcitabine for highly effective treatment of platinum-resistant ovarian cancer. Mol. Pharma. 2016, 13: 3665-3675 (IF: 4.296, 中科院JCR分区小类:2区)
11. Kaiyuan Ni#, Guangxu Lan#, Samuel S Veroneau, Xiaopin Duan, Yang Song, Wenbin Lin*, Nanoscale metal-organic frameworks for mitochondria-targeted radiotherapy-radiodynamic therapy. Nat. Commun. 2018, 9: 4321 (IF: 11.878, 中科院JCR分区小类:2区)
12. Ruoyu Xu#, Youfu Wang#, Xiaopin Duan, Kuangda Lu, Daniel Micheroni, Aiguo Hu, Wenbin Lin*, Nanoscale metal–organic frameworks for ratiometric oxygen sensing in live cells. J. Am. Chem. Soc. 2016, 138: 2158–2161 (IF: 14.695, 中科院JCR分区小类:1区)
13. Christina Chan#, Nining Guo#, Xiaopin Duan, Wenbo Han, Lai Xue, Darren Bryan, Sean C Wightman, Nikolai N Khodarev, Ralph R Weichselbaum, Wenbin Lin*, Systemic miRNA delivery by nontoxic nanoscale coordination polymers limits epithelial-to-mesenchymal transition and suppresses liver metastases of colorectal cancer, Biomaterials 2019, 210: 94-104 (IF: 10.273, 中科院JCR分区小类:1区)
14. Kaiyuan Ni#, Guangxu Lan#, Christina Chan, Xiaopin Duan, Nining Guo, Samuel S Veroneau, Ralph R Weichselbaum, Wenbin Lin*, Ultrathin Metal-Organic-Layer Mediated Radiotherapy-Radiodynamic Therapy, Matter 2019, in press (https://doi.org/10.1016/j.matt.2019.06.007). (新杂志,无影响因子及分区)