一、基本信息

 姓名：高学飞                                

 职称：教授

 联系邮箱：xgao2019smu@163.com

 

二、学习及工作经历

2019.9-   南方医科大学,基础医学院,教授

2018.2-2019.8   香港大学,生物医学院,研究助理教授

2011.8-2018.1   英国剑桥Sanger研究所,博士后/Staff Scientist

2006.9-2011.7 中国科学院广州生物医药与健康研究院,博士/助理研究员

1999.9-2006.7   安徽农业大学,动物科学/营养学,学士/硕士

 

三、拟招收博士后开展的研究方向

1.胚胎干细胞多能性调控机制；

2.胚胎干细胞命运决定与定向分化；

3.新型胚胎多能干细胞的建立及其应用。

 

四、代表性论文

1. Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Andy Chen CH Andy, Eckersley-Maslin M, Shakil A, Lee YL, Kobayashi T, Ryan D, Tam PL P, Ahmed A, Wu D, Nie T, Pei D, Surani A, Shang Z, Lai L, Yeung SBW, Teichmann S, Niemann H, Liu P. Establishment of Porcine and Human Expanded Potential Stem Cells. Nature Cell Biology, 2019.

2.Gao X, Jason CH Tsang, Fortis Gaba, Donghai Wu and Pentao Liu. Comparison of TALE Designer Transcription Factors and the CRISPR/dCas9 in Regulation of Gene Expression by Targeting Enhancers. Nucleic Acids Res, (2014).

3. Gao X, Yang J, Tsang JC, Ooi Jolene, Wu D, Liu P. Reprogramming to Pluripotency Using Designer TALE Transcription Factors Targeting Enhancers. Stem Cell Reports, 2013.

4. Gao X, Li K, Hui X, Kong X, Sweeney G, Wang Y, Xu A, Teng M, Liu P, Wu D. Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase. Biochem J, 2011.

5.Peng L, Gao X (Co-first author), Duan L, Ren X, Wu D, Ding K. Identification of pyrido[1,2- α]pyrimidine-4-ones as new molecules improving the transcriptional functions of estrogen-related receptor α. Journal of Medicinal Chemistry, 2011.

6. Gao X, Chen W, Kong XP, Xu AM, Wang ZG, Sweeney G, Wu D. Enhanced susceptibility of Cpt1c knockout mice to glucose intolerance induced by a high-fat diet involves elevated hepatic gluconeogenesis and decreased skeletal muscle glucose uptake. Diabetologia, 2009.