一、基本信息
姓名：赵存友
职称：教授
联系邮箱：cyzhao@smu.edu.cn
二、学习经历
2004.9-2008.1 香港科技大学，生物工程学专业，博士
2008.3-2009.6 香港科技大学，博士后
三、拟招收博士后开展的研究方向
1. 精神病遗传与表观遗传学研究（DNA甲基化修饰、非编码RNA参与疾病的生物学机制；大数据分析和挖掘）
四、主要学术任职
1. 中国中医药研究促进会心身医学专业委员会常委、
2. 中国遗传学会科学道德与伦理委员会委员、
3. 广东省医学会医学遗传学会常委、
4. 广东省医学会精神病学学会委员、
5. 广东省干细胞临床研究专家委员会委员、
6. 广州市精神病学会常委等职务
五、主要获奖情况
1. 教育部自然科学类2等奖，2010；
2. 广东省千百十工程省级培养对象，广东省教育厅，2014。
六、代表性论文
1) Li, S., L. Zong, Y. Hou, W. Zhang, L. Zhou, Q. Yang, L. Wang, W. Jiang, Q. Li, X. Huang, Z. Wen, Y. Ning and C. Zhao, Altered DNA methylation of the AluY subfamily in schizophrenia and bipolar disorder. Epigenomics, 2019.
2) Li, S., Q. Yang, Y. Hou, T. Jiang, L. Zong, Z. Wang, X. Luo, W. Liang, H. Zhao, Y. Ning, and C. Zhao, Hypomethylation of LINE-1 elements in schizophrenia and bipolar disorder. J Psychiatr Res, 2018. 107: 68-72.
3) Hou, Y., W. Liang, J. Zhang, Q. Li, H. Ou, Z. Wang, S. Li, X. Huang, and C. Zhao, Schizophrenia-associated rs4702 G allele-specific downregulation of FURIN expression by miR-338-3p reduces BDNF production. Schizophr Res, 2018. 199: 176-180.
4) Zong, L., L. Zhou, Y. Hou, L. Zhang, W. Jiang, W. Zhang, L. Wang, X. Luo, S. Wang, C. Deng, Z. Peng, S. Li, J. Hu, H. Zhao, and C. Zhao, Genetic and epigenetic regulation on the transcription of GABRB2: Genotype-dependent hydroxymethylation and methylation alterations in schizophrenia. J Psychiatr Res, 2017. 88: 9-17.
5) Chen, D., Y. Zuo, X. Zhang, Y. Ye, X. Bao, H. Huang, W. Tepakhan, L. Wang, J. Ju, G. Chen, M. Zheng, D. Liu, S. Huang, L. Zong, C. Li, Y. Chen, C. Zheng, L. Shi, Q. Zhao, Q. Wu, S. Fucharoen, C. Zhao, and X. Xu, A Genetic Variant Ameliorates b-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression. Am J Hum Genet, 2017. 101(1): 130-138.
6) Wang, L., W. Jiang, Q. Lin, Y. Zhang, and C. Zhao, DNA methylation regulates gabrb2 mRNA expression: developmental variations and disruptions in l-methionine-induced zebrafish with schizophrenia-like symptoms. Genes Brain Behav, 2016. 15(8): 702-710.
7) Zhao, C. and H. Xue, A simple method for high-throughput quantification of genome-wide DNA methylation by fluorescence polarization. Epigenetics, 2012. 7(4): 335-339.
8) Zhao, C., F. Wang, F.W. Pun, L. Mei, L. Ren, Z. Yu, S.K. Ng, J. Chen, S.Y. Tsang, and H. Xue, Epigenetic regulation on GABRB2 isoforms expression: developmental variations and disruptions in psychotic disorders. Schizophr Res, 2012. 134(2-3): 260-266.
9) Zhao, C., Z. Xu, F. Wang, J. Chen, S.K. Ng, P.W. Wong, Z. Yu, F.W. Pun, L. Ren, W.S. Lo, S.Y. Tsang, and H. Xue, Alternative-splicing in the exon-10 region of GABA(A) receptor beta(2) subunit gene: relationships between novel isoforms and psychotic disorders. PLoS One, 2009. 4(9): e6977.
10) Zhao, C., Z. Xu, J. Chen, Z. Yu, K.L. Tong, W.S. Lo, F.W. Pun, S.K. Ng, S.Y. Tsang, and H. Xue, Two isoforms of GABA(A) receptor beta2 subunit with different electrophysiological properties: Differential expression and genotypical correlations in schizophrenia. Mol Psychiatry, 2006. 11(12): 1092-1105
