窗体顶端
一、基本信息
姓名：李晓娟
职称：教授
联系邮箱：lixiaoj@smu.edu.cn
二、学习经历
1993.9-1997.7 广州中医药大学,中药学,学士
1997.9-2000.7 广州中医药大学,中西医结合，硕士
2000.9-2003.7 广州中医药大学，中西医结合，博士
2003.7-2005.7 日本神户药科大学，药理学，博士后
三、拟招收博士后开展的研究方向
抗炎免疫药理学
四、主要学术任职
1. 世界中医药联合会中医药免疫专业委员会，常务理事
2. 中国药理学会抗炎免疫药理学分会，常务委员
3. 广东省药理学会药物筛选与评价专业委员会，常务委员
4. 广东省药理学会中药药理专业委员，常务委员
五、代表性论文
1. Zheng XZ, He LG, Wang S, Wang K, Zhang YY, Tao L, Li XJ*, Liu SW*. Aconine suppresses osteoclastogenesis via down-regulation of NF-κB and NFATc1 activation and expression of DC-STAMP. Acta Pharmacol Sin. 2015; in press ；
2. 李珉珉；张瑞涛；胡义平；李建军；姜世勃；李晓娟；刘叔文.HIV进入抑制多肽VIR576可抑制抗原特异性CD4+T细胞的体外活化:一种潜在的双功能杀微生物剂(英文)南方医科大学学报，2014(5): 597-602 ；
3. He LG, Li XL, Zeng XZ, Duan H, Wang S, Lei LS, Li XJ*, Liu SW*. Sinomenine induces apoptosis in RAW 264.7 cell-derived osteoclasts in vitro via caspase-3 activation. Acta Pharmacol Sin. 2014 Feb;35(2):203-10. (IF:2.354) ；
4. Li X, He L, Hu Y, Duan H, Li X, Tan S, Zou M, Gu C, Zeng X, Yu L, Xu J, Liu S.Sinomenine suppresses osteoclast formation and Mycobacterium tuberculosis H37Ra-induced bone loss by modulating RANKL signaling pathways，PLoS One. 2013 Sep 16;8(9):e74274. (IF:3.73) ；
5. Lun Y, Xia H, Zhang Q, Yu C, Chen N, Li X, Liu S, Lei L. Anti-inflammatory and immunosuppressive activities of 1,3-dicyclopentyl-1,2,3,6- tetrahydropyrimidine -4,5-dicarboxylic acid diethyl ester (ZL-5015).Int Immunopharmacol. 2013 Oct; 17(2):168-77. (IF: 2.417) ；
6. Li X, Zhong H, Bao W, Boulad N, Evangelista J, Haider M, Bussel J, Yazdanbakhsh K. Defective regulatory B cell compartment in patients with immune thrombocytopenia (ITP). Blood, 2012，Oct 18;120(16):3318-25. (IF:9.898)
评论: Blood, Oct 18;120(16):3169. (IF:9.898) ；
7. Li X, Hu Y, He L, Wang S, Zhou H, Liu S. Icaritin inhibits T cell activation and prolongs skin allograft survival in mice. Int Immunopharm, 2012, May, 13(1) :1-7 (IF:2.417) ；
8. Zhong H, Bao W, Li X, Miller A, Seery C, Haq N, Bussel J, Yazdanbakhsh K. CD16+ monocytes control T cell subset development in immune thrombocytopenia. Blood. 2012 Aug 20, Blood, Oct 18;120(16):3326-35. (IF:9.898) ；
9. Bao W, Zhong H, Li X, Lee MT, Schwartz J, Sheth S, Yazdanbakhsh K. Immune regulation in allo-antibody responder and non-responder chronically transfused patients with sickle cell disease and b-thalassemia major. Am J Heamatol. 2011 Dec;86(12):1001-6. (IF 4.671) ；
10. Qi Z, Pan C, Lu H, Shui Y, Li L, Li X, Xu X, Liu S, Jiang S. A recombinant mimetics of the HIV-1 gp41 prehairpin fusion intermediate fused with human IgG Fc fragment elicits neutralizing antibody response in the vaccinated mice. Biochem Biophys Res Commun. 2010 Jul 30;398(3):506-12. (IF: 2.484) ；
11. Wang H, Qi Z, Guo A, Mao Q, Lu H, An X, Xia C, Li X, Debnath AK, Wu S, Liu S, Jiang S. ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation. Antimicrob Agents Chemother. 2009 Dec;53(12):4987-98. (IF:4.841) ；
12. Yamaki K, Li X, Hossain MA, Alam AH, Taneda S, Yanagisawa R, Takano H, Yoshino S.Difference in preventive effects between the phosphodiesterase iv inhibitor rolipram and anti-arthritic drugs on antigen-induced arthritis in mice. Immunol Invest. 2007;36(2):131-45 (IF:1.270) ；
13. Li XJ, Yue PY, Ha WY, Wong DY, Tin MM, Wang PX, Wong RN, Liu L. Effect of sinomenine on gene expression of the IL-1beta-activated human synovial sarcoma. Life Sci. 2006 ;79(7):665-73 (IF: 2.527) ；
14. Ha WY, Li XJ, Yue PY, Wong DY, Yue KK, Chung WS, Zhao L, Leung PY, Liu L, Wong RN. Gene expression profiling of human synovial sarcoma cell line (Hs701.T) in response to IL-1beta stimulation. Inflamm Res. 2006;55(7):293-9.(IF:2.004)
