一、基本信息
姓名：陈金香
职称：教授
联系邮箱：jxchen@smu.edu.cn
二、学习经历
1996.9-2000.6 安徽师范大学，应用化学专业，获学士学位
2000.9-2003.6 苏州大学，无机化学专业，获硕士学位
2003.9-2006.6 苏州大学，有机化学专业，获博士学位
三、拟招收博士后开展的研究方向
基于纳米材料的疾病精准诊断与治疗
四、代表性论文
1. Shi-Xin Lin, Wei-Lun Pan, Ru-Jie Niu, Yan Liu, Jin-Xiang Chen,* Wen-Hua Zhang,* Jian-Ping Lang* and David J. Young, Effective loading of cisplatin into a nanoscale UiO-66 metal–organic framework with preformed defects, Dalton Trans., 2019, 48, 5308–5314.
2. Shao-Lan Cai, Zi-Chuan Yang, Ke-Yang Wu, Cheng Fan, Ling-Yan Zhai, Nai-Han Huang, Rong-Tian Li, Wen-Jun Duan* and Jin-Xiang Chen*, Experimental and computational investigation of a DNA-shielded 3D metal-organic framework for the prompt dual sensing of Ag+ and S2−. RSC adv. 2019, 9, 15424‒15430.
3. Nai-Han Huang, Rong-Tian Li, Cheng Fan, Ke-Yang Wu, Zhe Zhang, Jin-Xiang Chen* Rapid sequential detection of Hg2+ and biothiols by a probe DNA-MOF hybrid sensory system, J. Inorg. Biochem., 2019, 197, 110690.
4. Ke-Yang Wu, Liang Qin, Cheng Fan, Shao-Lan Cai, Bin Sun, Bao-Ping Xie, Xiao-Yan Tang* and Jin-Xiang Chen* Sequential and Recyclable Sensing of Fe3+ and Ascorbic Acid Based on a Water-stable Green-emitting Terbium(III) Metal−Organic Framework, Dalton Trans., 2019, 48, 8911-8919.
5. Bao-Ping Xie, Gui-Hua Qiu, Bin Sun, Zi-Feng Yang, Wen-Hua Zhang,* Jin-Xiang Chen,* Zhi-Hong Jiang* Synchronous sensing of three conserved sequences of Zika virus by a DNAs@MOF hybrid: Experimental and molecular simulation studies, Inorg. Chem. Frontier. 2019, 6, 148-152.
6. Ling-Yan Zhai#, Min-Xiang Li#, Wei-Lun Pan, Yun Chen, Min-Min Li, Jian-Xin Pang, Lei Zheng*, Jin-Xiang Chen*, Wen-Jun Duan*, In Situ Detection of Plasma Exosomal MicroRNA-1246 for Breast Cancer Diagnostics by a Au Nanoflare Probe, ACS Appl. Mater. Inter. 2018, 10, 39478-39486.
7. Xiang-Ming Hu#, Rong-Tian Li#, Miao-Miao Zhang, Ke-Yang Wu, Huan-Huan Li, Nai-Han Huang, Bin Sun*, Jin-Xiang Chen* Phenanthroline-linked berberine dimer and fluorophore-tagged DNA conjugate for the selective detection of microRNA-185: experimental and molecular docking studies, Anal. Chim. Acta, 2019, 1051, 153-159.
8. Pei-Pei Hu, Ning Liu, Ke-Yang Wu, Ling-Yan Zhai, Bao-Ping Xie, Bin Sun, Wen-Jun Duan, Wen-Hua Zhang,* and Jin-Xiang Chen* Successive and Specific Detection of Hg2+ and I− by a DNA@MOF Biosensor: Experimental and Simulation Studies, Inorg. Chem. 2018, 57(14), 8382-8389.
9. Bao-Ping Xie#, Gui-Hua Qiu#, Pei-Pei Hu, Zhen Liang, Ye-Mei Liang, Bin Sun, Li-Ping Bai, Zhi-Hong Jiang, Jin-Xiang Chen∗ Simultaneous detection of Dengue and Zika virus RNA sequences with a three-dimensional Cu-based zwitterionic metal−organic framework, comparison of single and synchronous fluorescence analysis, Sensor. Actuat. B-Chem. 2018, 254C, 1133-1140.
10. Bin Sun1, Zhen Liang1, Bao-Ping Xie, Rong-Tian Li, Lin-Ze Li, Zhi-Hong Jiang, Li-Ping Bai, Jin-Xiang Chen∗, Fluorescence sensing platform based on ruthenium(II) complexes as high 3S (sensitivity, specificity, speed) and “on-off-on” sensors for the miR-185 detection, Talanta, 2018, 179, 658-667.
11. Gui-Hua Qiu, Zi-Hua Weng, Pei-Pei Hu, Wen-Jun Duan, Bao-Ping Xie, Bin Sun, Xiao-Yan Tang, Jin-Xiang Chen*, Synchronous detection of ebolavirus conserved RNA sequences and ebolavirus-encoded miRNA-like fragment based on a zwitterionic copper (II) metal–organic framework, Talanta, 2018, 180, 396-402.
12. Liang Qin,# Zi-Yan Sun,# Kai Cheng, Shu-Wen Liu, Jian-Xin Pang, Li-Ming Xia, Wen-Hua Chen,* Zhen Cheng,* and Jin-Xiang Chen* Zwitterionic manganes and gadolinium metal–organic frameworks as efficient magnetic resonance contrast agents for in vivo imaging, ACS Appl. Mater. Inter. 2017, 9(47), 41378-41386.
13. Shui-Ping Yang, Wei Zhao, Pei-Pei Hu, Ke-Yang Wu, Zhi-Hong Jiang, Li-Ping Bai, Min-Min Li, and Jin-Xiang Chen*, Lanthanum-based metal−organic frameworks for specific detection of Sudan virus RNA conservative sequences down to single-base mismatch, Inorg. Chem. 2017, 56, 14880-14887.
14. Gui-Hua Qiua,1 Wan-Zhen Lu1, Pei-Pei Hu, Zhi-Hong Jiang, Li-Ping Bai, Tao-Rui Wang, Min-Min Li, * Jin-Xiang Chen,* A metal-organic framework based PCR-free biosensor for the detection of gastric cancer associated microRNAs, J. Inorg. Biochem. 2017, 177, 138-142.
15. Bin Su1, Hai-Qing Zha1, Bao-Ping Xie, Li-Ping Bai, Zhi-Hong Jiang, Jin-Xiang Chen,* Sequence-specific fluorometric recognition of HIV-1 ds-DNA by using zwitterionic zinc(II)-carboxylate polymers, J. Inorg. Biochem. 2017, 176, 17-23.
16. Hai-Qing Zhao1, Gui-Hua Qiu1, Zhen Liang, Min-Min Li, Bin Sun, Liang Qin, Shui-Ping Yang, Wen-Hua Chen, Jin-Xiang Chen*, A Zinc(II)-based two-dimensional MOF for sensitive and selective sensing of HIV-1 ds-DNA sequences, Anal. Chim. Acta, 2016, 922, 55-63.
17. Hai-Qing Zhao,‡ Shui-Ping Yang,‡ Ni-Ni Ding, Liang Qin, Gui-Hua Qiu, Jin-Xiang Chen,* Wen-Hua Zhang,* Wen-Hua Chen* and T. S. Andy Hor* A zwitterionic 1D/2D polymer co-crystal and its polymorphic sub-components: a highly selective sensing platform for HIV ds-DNA sequences, Dalton Trans., 2016, 45, 5092–5100.
18. Liang Qin, Li-Xian Lin, Zhi-Ping Fang, Shui-Ping Yang, Gui-Hua Qiu, Jin-Xiang Chen* and Wen-Hua Chen* A water-stable metal-organic framework of a zwitterionic carboxylate with dysprosium: a sensing platform for Ebolavirus RNA sequences, Chem. Commu. 2016, 52, 132-135.
19. Shui-Ping Yang, Shao-Rui Chen, Shu-Wen Liu, Xiao-Yan Tang, Liang Qin, Gui-Hua Qiu, Jin-Xiang Chen,* Wen-Hua Chen,* Platforms formed from a 3D Cu-based zwitterionic metal−organic framework and probe ss-DNA: selective fluorescent biosensors for HIV-1 ds-DNA and Sudan virus RNA sequences, Anal. Chem. 2015, 87, 12206-12214.
20. Ming Chen, Xiao-Yan Tang, Shui-Ping Yang, Huan-Huan Li, Hai-Qing Zhao, Zhi-Hong Jiang, Jin-Xiang Chen,* Wen-Hua Chen,* Five water-soluble zwitterionic copper(II)-carboxylate polymers: role of dipyridyl coligands in enhancing the DNA-binding, cleaving and anticancer activities, Dalton Trans. 2015, 44, 13369-13377.
21. Ming Chen, Xiao-Yan Tang, Ming-Zhen Chen, Jin-Xiang Chen*, Wen-Hua Chen*, Lanthanide based Polymers with Charged Ligand Backbones: Triple-stranded Chain Structures and their DNA Cleavage Studies, Aust. J Chem. 2015, 48, 493-499.
22. Zi-Xuan Zhang, Ni-Ni Ding, Wen-Hua Zhang*, Chen, Jin-Xiang*, Young, David J.*, Andy Hor, T. S.* Stitching 2D Polymeric Layers into Flexible Interpenetrated Metal–Organic Frameworks within Single Crystals, Angew. Chem. Int. Ed. 2014, 53, 4628-4632.
23. Jin-Xiang Chen,* Ming Chen, Ni-Ni Ding, Wen-Hua Chen, Wen-Hua Zhang,* Andy Hor, T. S.*; Young, David J. * Transmetalation of a Dodecahedral Na9 Aggregate-based Polymer: a Facile Route to Water Stable Cu(II) Coordination Networks, Inorg. Chem. 2014, 53, 7446-7545.
24. Jin-Xiang Chen*, Hai-Qing Zhao, Huan-Huan Li, Sheng-Li Huang, Ni-Ni Ding, Wen-Hua Chen, Young, David J.; Wen-Hua Zhang*, Andy Hor, T. S*. Bent Tritopic Carboxylates for Coordination Networks: Clues to the Origin of Self-penetration, CrystEngComm. 2014, 16, 7722-7730.
专利
1. Chen, Jin-Xiang; Xie, Bao-Ping; Qiu, Gui-Hua; Hu, Pei-Pei; Liang, Zhen; Liang, Ye-Mei; Sun, Bin; Bai, Li-Ping; Jiang, Zhi-Hong; Crystalline copper-based coordination polymers and their use. 澳洲发明专利，专利号：AU: 2017100590
2. Chen, Jin-Xiang; Sun, Bin; Xie, Bao-Ping; Jiang, Zhi-Hong; Bai, Li-Ping; Crystalline lanthanum-carboxylate coordination polymers and their use. 澳洲发明专利，AU: 2017100565
3. Chen, Jin-Xiang; Sun, Bin; Zhao, Hai-Qing; Xie, Bao-Ping; Bai, Li-Ping; Jiang, Zhi-Hong; Zwitterionic zinc(II) carboxylate compounds and their use. 澳洲发明专利。专利号：AU: 2016101528
4. Chen, Jin-Xiang; Pang, Jian-Xin; Liu, Shu-Wen; Bai, Li. Ping; Jiang, Zhi-Hong; Crystalline contrast agent for magnetic resonance imaging, kit and composition comprising it and their use. 澳洲发明专利，专利号：AU: 2016101702
5. Chen, Jin-Xiang; Sun, Bin; Zhao, Hai-Qing; Xie, Bao- Ping; Bai, Li-Ping; Jiang, Zhi-Hong; Zwitterionic zinc(II) carboxylate compounds and their use.美国发明专利，专利号：US 10,023,594 B2
6. Chen, Jin-Xiang; Sun, Bin; Xie, Bao-Ping; Jiang, Zhi-Hong; Bai, Li-Ping; Crystalline lanthanum-carboxylate coordination polymers and their use. 美国发明专利，专利号：US 10.260.114 B2。
7. 陈金香，杨水平，陈文华，一种两性羧酸镧金属有机骨架及其合成方法和应用，申请号：201510952885.X
8. 授权日：2018年12月4日，专利号：ZL2015 1 0952885.X
9. 陈金香，覃亮，陈文华，刘叔文，庞建新，一种基于锰的两性羧酸金属配位聚合物及其制备方法，中国发明专利，专利号：ZL 2016 1 0404049.2
10. 陈金香，覃亮，陈文华，刘叔文，庞建新，一种基于钆的两性羧酸金属配位聚合物及其制备方法，中国发明专利，专利号：ZL 2016 1 0403497.0
11. 陈金香，覃亮，陈文华，刘叔文，谢宝平，孙斌，一种两性羧酸四核铜金属配位聚合物及其制备方法，专利号：ZL 2016 1 0403491.3
12. 陈金香，覃亮，陈文华，刘叔文，谢宝平，孙斌，一种两性羧酸双核铜金属配位聚合物及其制备方法，中国发明专利，专利号：ZL 201610404106.7
13. 陈金香，覃亮，陈文华，刘叔文，谢宝平，孙斌，一种两性羧酸六核铜金属配位聚合物及其制备方法，中国发明专利，专利号：ZL 201610404108.6
