一、基本信息

姓名：周中振                                 

职称：教授

联系邮箱：zhouzz@smu.edu.cn

 

二、学习经历

1997.9-2001.7   武汉化工学院制药系，本科，工学学士学位；

2001.9-2007.7   华中师范大学农药与化学生物学教育部重点实验室，有机化学专业，博士研究生，理学博士学位

 

三、拟招收博士后开展的研究方向

药物分子设计、合成及性质研究，主要围绕神经系统疾病相关药物研究

 

四、主要学术任职

广东省药学会药物化学专业委员会，委员

 

五、主要获奖情况

1. 广东省高等学校优秀青年教师培养计划培养对象，2014;

2. 广东省高等学校“千百十工程”第五批校级培养对象，2008

 

六、代表性论文

1. Tang, Lv; Huang, Chang; Zhong, Jiahong; He, JiaPeng; Guo, Jiayin; Liu, Menghua; Xu, Jiang-Ping*; Wang, Hai-Tao; Zhou Zhong-Zhen* Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect.. European Journal of Medicinal Chemistry, 2019, 168, 221-231. (SCI, IF = 4.81, 小类I区).

2. Zhou ZhongZhen; Liu, Mingxin; Lv, Leiyang; Li, Chao-Jun. Silver(I)-Catalyzed Widely Applicable Aerobic 1,2-Diol Oxidative Cleavage. Angewandte Chemie International Edition, 2018, 57 (10), 2616-2620. (SCI, IF = 12.10, I区Top期刊).

3. Zhou ZhongZhen; Liu, Mingxin; Li, Chao-Jun. Selective Copper–N-Heterocyclic Carbene (Copper-NHC)-Catalyzed Aerobic Cleavage of β-1 Lignin Models to Aldehydes. ACS Catalysis, 2017, 7 (5), 3344-3348. (SCI, IF = 11.38, I区Top期刊).

4. Zhou Zhong-Zhen*; Shi, Xiu-Dong; Feng, Hong-Fang; Cheng, Yu-Fang; Wang, Hai-Tao; Xu, Jiang-Ping*. Discovery of 9H-purins as potential tubulin polymerization inhibitors: Synthesis, biological evaluation and structure−activity relationships. European Journal of Medicinal Chemistry, 2017, 138, 1126-1134. (SCI, IF = 4.81, 小类I区).

5. Zhou Zhong-Zhen*; Cheng, Yu-Fang; Zou, Zheng-Qiang; Ge, Bing-Chen; Yu, Hui; Huang, Cang; Wang, Hai-Tao; Yang, Xue-Mei*; Xu, Jiang -Ping*. Discovery of N-Alkyl catecholamides as selective phosphodiesterase-4 Inhibitors with anti-neuroinflammation potential Exhibiting antidepressant-like effects at non-emetic Doses. ACS Chemical Neuroscience, 2017, 8 (1), 135-146. (SCI, IF = 4.21, 小类I区).

6. Ge, Bing-Chen; Feng, Hong-Fang; Cheng, Yu-Fang; Wang, Hai-Tao; Xi, Bao-Ming; Yang, Xue-Mei; Xu, Jiang-Ping*; Zhou Zhong-Zhen*. Design, synthesis and biological evaluation of substituted aminopyridazin-3(2H)-ones as G0/G1-phase arresting agents with apoptosis-inducing activities. European Journal of Medicinal Chemistry, 2017, 141 , 440-445. (SCI, IF = 4.81, 小类I区).

7. Zhou Zhong-Zhen*; Ge, Bing-Chen; Zhong, Qiu-Ping; Huang, Chang; Cheng, Yu-Fang; Yang, Xue-Mei; Wang, Hai-Tao; Xu, Jiang-Ping*. Development of highly potent phosphodiesterase 4 inhibitors with anti-neuroinflammation potential: Design, synthesis, and structure-activity relationship study of catecholamides bearing aromatic rings. European Journal of Medicinal Chemistry, 2016, 124, 372-379. (SCI, IF = 4.81, 小类I区).

8. Huang, Chang; Zhong, Qiu-Ping; Tang, Lv; Wang, Hai-Tao; Xu, Jiang-Ping*; Zhou Zhong-Zhen*. Discovery of 2-(3,4-dialkoxyphenyl)-2-(substituted pyridazin-3-yl) acetonitriles as phosphodiesterase 4 inhibitors with anti-neuroinflammation potential based on three-dimensional quantitative structure-activity relationship study. Chemical Biology & Drug Design 2019, 93 (4), 484-502. (SCI, IF = 2.33, III区).

9. Liu, Yi; Nie, Gang; Zhou Zhong-Zhen*; Jia, Lihui; Chen, Yunfeng*. Copper-Catalyzed Oxidative Cross-Dehydrogenative Coupling/Oxidative Cycloaddition: Synthesis of 4-Acyl-1,2,3-Triazoles. The Journal of Organic Chemistry, 2017, 82 (17), 9198-9203. (SCI, IF = 4.80, II区).

 

专利

1. 周中振，汤侣，徐江平. 一种1-芳基-3-(6-芳基吡啶-2-基）-丙烯酮及其制备方法与应用，中国专利，专利申请号：201910633037.0。

2. 周中振，徐江平，黄昌，汪海涛. 3-芳基-4-烷氧基苄胺类衍生物的合成及其应用，中国专利，专利申请号：201810964371.X。

3. 周中振，徐江平，黄昌，汪海涛. 3-芳基-4-烷氧基苄醚类衍生物的合成及其应用， 中国专利，专利申请号：201810964506.2。

4. 徐江平，周中振，一种能避免呕吐反应的磷酸二酯酶4抑制剂，2014.2.12-2034.2.11，中国，ZL 201210037980.3。

5. 周春琼，周中振，一种对称的多胺与吡咯聚酰胺缀合物及其制备方法。2011.09.14-2031.09.13，中国，ZL 20091019414.6