一、基本信息
姓名：李金龙
职称：教授
联系邮箱：lijinlong@smu.edu.cn
二、学习经历
1993.9-1996.7 临沂医学专科学校，临床医学专业，
2000.9-2003.7 郑州大学，病理与病理生理专业，硕士
2003.9-2006.7 中山大学，肿瘤学专业，博士
2006.9-2008.9 香港科技大学，博士后
三、拟招收博士后开展的研究方向
1. 自噬在肿瘤干细胞中作用；
2. 休眠肿瘤细胞的免疫逃逸；
3. 昼夜节律对肿瘤细胞休眠及干性转化的影响
四、代表性论文
1. Zhang Y, Xu L, Wang P, Jian H, Shi X, Jia M, Mo L, Hu Z, Li H, Li J: Phenotypic transition of tumor cells between epithelial- and mesenchymal-like state during adaptation to acidosis. Cell Cycle 2019, 18:1938-1947.
2. Zhang X, Shi X, Li J, Hu Z, Gao J, Wu S, Long Z: Combination immunotherapy with interleukin-2 surface-modified tumor cell vaccine and programmed death receptor-1 blockade against renal cell carcinoma. Cancer Sci 2019, 110:31-39.
3. Shi X, Chen S, Zhang Y, Xie W, Hu Z, Li H, Li J, Zhou Z, Tan W: Norcantharidin inhibits the DDR of bladder cancer stem-like cells through cdc6 degradation. Onco Targets Ther 2019, 12:4403-4413.
4. Zhang X, Shi X, Li J, Mo L, Hu Z, Gao J, Wu S, Long Z: PD-1 Blockade Overcomes Adaptive Immune Resistance in Treatment with Anchored-GM-CSF Bladder Cancer Cells Vaccine. J Cancer 2018, 9:4374-4381.
5. Cai X, She M, Xu M, Chen H, Li J, Chen X, Zheng D, Liu J, Chen S, Zhu J, et al: GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction. Int J Biol Sci 2018, 14:1696-1708.
6. Liu J, Li Q, Li X, Qiu Z, Li A, Liang W, Chen H, Cai X, Chen X, Duan X, et al: Zika Virus Envelope Protein induces G2/M Cell Cycle Arrest and Apoptosis via an Intrinsic Cell Death Signaling Pathway in Neuroendocrine PC12 Cells. Int J Biol Sci 2018, 14:1099-1108.
7. Chen Q, Mo L, Cai X, Wei L, Xie Z, Li H, Li J, Hu Z: ICOS signal facilitates Foxp3 transcription to favor suppressive function of regulatory T cells. Int J Med Sci 2018, 15:666-673.
8. Qin D, Li L, Li J, Li J, Zhao D, Li Y, Li B, Zhang X: A New Compound Isolated from the Reduced Ribose-Tryptophan Maillard Reaction Products Exhibits Distinct Anti-inflammatory Activity. J Agric Food Chem 2018, 66:6752-6761.
9. Mo L, Zhang X, Shi X, Wei L, Zheng D, Li H, Gao J, Li J, Hu Z: Norcantharidin enhances antitumor immunity of GM-CSF prostate cancer cells vaccine by inducing apoptosis of regulatory T cells. Cancer Sci 2018, 109:2109-2118.
10. Mao Y, Pei N, Chen X, Chen H, Yan R, Bai N, Li A, Li J, Zhang Y, Du H, et al: Angiotensin 1-7 Overexpression Mediated by a Capsid-optimized AAV8 Vector Leads to Significant Growth Inhibition of Hepatocellular Carcinoma In vivo. Int J Biol Sci 2018, 14:57-68.
11. Shi X, Zhang X, Li J, Mo L, Zhao H, Zhu Y, Hu Z, Gao J, Tan W: PD-1 blockade enhances the antitumor efficacy of GM-CSF surface-modified bladder cancer stem cells vaccine. Int J Cancer 2018, 142:2106-2117.
12. Cai X, Li J, Wang M, She M, Tang Y, Li J, Li H, Hui H: GLP-1 Treatment Improves Diabetic Retinopathy by Alleviating Autophagy through GLP-1R-ERK1/2-HDAC6 Signaling Pathway. Int J Med Sci 2017, 14:1203-1212.
13. Mo L, Chen Q, Zhang X, Shi X, Wei L, Zheng D, Li H, Gao J, Li J, Hu Z: Depletion of regulatory T cells by anti-ICOS antibody enhances anti-tumor immunity of tumor cell vaccine in prostate cancer. Vaccine 2017, 35:5932-5938.
14. Zheng D, Ye S, Wang X, Zhang Y, Yan D, Cai X, Gao W, Shan H, Gao Y, Chen J, et al: Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity. Sci Rep 2017, 7:2854.
15. Chen S, Chen X, Xie G, He Y, Yan D, Zheng D, Li S, Fu X, Li Y, Pang X, et al: Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells. Oncotarget 2016, 7:40362-40376.
16. He Y, Yan D, Zheng D, Hu Z, Li H, Li J: Cell Division Cycle 6 Promotes Mitotic Slippage and Contributes to Drug Resistance in Paclitaxel-Treated Cancer Cells. Plos One 2016, 11:e162633.
17. Li J, Luo J, Gu D, Jie F, Pei N, Li A, Chen X, Zhang Y, Du H, Chen B, et al: Adenovirus-Mediated Angiotensin II Type 2 Receptor Overexpression Inhibits Tumor Growth of Prostate Cancer In Vivo. J Cancer 2016, 7:184-191.
