李妍教授

【 发布日期: 11-19 】 【 浏览次数: 】 【 作者: 】


 

 

一、基本信息

姓名:李妍                                 

职称:教授

联系邮箱:liyan_nys@hotmail.com

 

二、学习经历

1989.9-1994.7 白求恩医科大学(现吉林大学),医药信息学专业,学士

2001.9-2004.7 第一军医大学(现南方医科大学),免疫学专业,硕士

2004.9-2007.7 南方医科大学,免疫学专业,博士

2008.1-2009.1 加拿大多伦多大学附属St.Micheals 医院 ,博士后

 

三、拟招收博士后开展的研究方向

1. 幽门螺杆菌感染免疫;

2. Notch信号通路对于病原体诱导的CD4+T细胞分化的调控作用

 

四、代表性论文

1. Lin Y, Ye J, Luo M,Hu B, Wu D, Wen J, Chen Z, Yang C, Ning L, Li Y*Ning Y. Group B Streptococcus DNA copy numbers measured by digital PCR correlates with perinatal outcomes. Anal Chem. 2019, 91(15): 9466-9471.

2. Ning Y, Ye J, Wen J, Wu D, Chen Z, Lin Y, Hu B, Luo M, Luo J,Ning L, Li Y*. Identification of two Lpp20 CD4+ T cell epitopes in helicobacter pylori-infected subjects. Front. Microbiol, 2018,9:884.

3. Ye J, Wen J, Ning Y,Li Y*. High notch expression implies poor survival in pancreatic ductal adenocarcinoma: A systematic review and meta-analysis. Pancreatology, 2018, 18(8):954-961.

4. Li Y, Chen Z, Ye J, Ning L, Luo J, Zhang Li, Jiang Y, Xi Y, Ning Y. Antibody production and Th1-biased response induced by an epitope vaccine composed of cholera toxin B unit and Helicobacter pylori Lpp20 epitopes. Helicobacter, 2016,21(3):234-48

5. Li Y, Zhou M, Zhou H, Ning Y. The last intron of the human thrombopoietin gene enhances expression in milk of transgenic mice. Funct Integr Genomics. 2014 14(1):229-36

6. Li Y, Jiang Y, Xi Y, Zhang L, Luo J, He D, Zeng S,Ning Y.Identification and characterization of H-2d restricted CD4+ T cell epitopes on Lpp20 of Helicobacter pylori. BMC Immunology, 2012, 13(1):68.

7. Li Y, Ning Y, Wang Y, Peng D, Jiang Y, Zhang L, Long M, Luo J, Li M. Mimotopes selected with a neutralizing antibody against urease B from Helicobacter pylori induce enzyme inhibitory antibodies in mice upon vaccination. BMC Biotechnology, 2010, 10:84.

8. Li Y, Ning YS, Wang YD, Luo J, Wang W, Dong WQ, Li M. Production of Mouse monoclonal antibodies against Helicobacter pylori Catalase and mapping the antigenic epitope by phage display library. Vaccine, 2008, 26(9): 1263-1269.

9. Li Y, Ning YS, Wang YD, Hong YH, Luo J, Dong WQ, Li M. Production of Mouse Monoclonal Antibodies against Helicobacter pylori Lpp20 and Mapping the Antigenic Epitope by Phage Display Library. Journal of Immunological Methods,2007,325 (1-2):1-8.

10. Lê KA,Li Y(共同第一), Xu X, Yang W, Liu T, Zhao X, Tang YG, Cai D, Go VL, Pandol S, Hui H.Alterations in Fecal Lactobacillus and Bifidobacterium Species in Type 2 Diabetic Patients in Southern China Population. Front Physiol. 2013;3:496 novel target for anti-platelet therapy. Blood. 2017,129(13):1840-1854. doi: 10.1182/blood-2016-07-729400.