一、基本信息
姓名：张庆玲
职称：教授/副主任医师
联系邮箱：zqllc8@126.com
二、学习经历
1996.9-1999.7 第三军医大学，肿瘤学专业，硕士
2003.9-2006.7 第一军医大学，病理学与病理生理学专业，博士
三、拟招收博士后开展的研究方向
1. 肿瘤发生机制研究；
2. 消化道肿瘤转移机制及靶向药物开发研究；
3. 肿瘤液体活检精准诊断新技术开发；
4. 肿瘤生物信息分析及应用研究。
四、主要学术任职
1. 世界华人医师协会检验与病理医师协会，常委；
2. 中国抗癌协会肿瘤微环境专业委员会，委员；
3. 中国抗癌协会肿瘤病理专业委会淋巴瘤学组，成员；
4. 中国老年医学会病理学分会，委员；
5. 广东省中西医结合学会病理学专业委员会，常委；
6. 广东省医疗行业协会病理医学管理分会，常委
7. 研究型医院协会病理学分会原发不明肿瘤学组，委员；
8. 广东省胸部疾病学会乳腺病防治专业委员会，委员。
五、主要获奖情况
1. 中国医学科技技术一等奖，2005；
2. 军队科技进步二等奖，2004
六、代表性论文
1. Gui-fang Zhu, Wen-xia Ma, Yang-wei Xu, Hui-lin Niu, Jia Xu, Pei-Rong Zhou, Jian Li, Xia Liu, Dan-li Ye, Xiao-rong Liu, Tao Yan, Wei-ke Zhai, Zhi-jun Xu, Chun Liu, Hao Wang, Lei Wang, Jia-mao. Luo, Li Liu, Xuan-qi Li, Suiqun Guo, Peng Shen, Hui-Ping Jiang, Hui-Kuan Lin, Dihua Yu, Yan-Qing Ding, Qing-ling Zhang（张庆玲）*. Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression. Nature Communications, 2019. 10(1): p. 112.（通讯作者）；
2. Danli Ye, Wenxia Ma, Jiahui Xu, Guifang Zhu, Deying Liu, Chun Liu, Yanqing Ding, Qing-ling Zhang（张庆玲）*. WTX inhibits gastric cancer migration through the reversal of epithelial‑mesenchymal transition. Oncology Letters.2018;16:4970-4976（通讯作者）；
3. HaoWang1,2¶, Jiamao Luo1,2¶, Chun Liu1,2¶, Huilin Niu1,2, Jing Wang3, Qi Liu3, Zhongming Zhao4, Hua Xu4, Yanqing Ding1,2,Jingchun Sun4*, Qingling Zhang1,2*. Investigating MicroRNA and transcription factor co-regulatory networks in colorectal cancer. BMC Bioinformatics. 2017:18:388. https://doi.org/10.1186/s12859-017-1796-4. (通讯作者)；
4. Yao-Yao Zhang, Qi-Ming Wang, Hui-Lin Niu, Xia Liu, Qing-ling Zhang（张庆玲）*. The General Expression Analysis of WTX Gene in Normal and Cancer Tissues. Pathology & Oncology Research. 2017 , 23 (2) :1-8. (通讯作者)；
5. Jiahui Xu; Deying Liu; Guifang Zhu; Danli Ye; Yangwei Xu; Jian Li; Huilin Niu; Qing-ling Zhang（张庆玲）*. Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer. Journal of Experimental & Clinical Cancer Research. 2017 Jan 26;36(1):19. doi: 10.1186/s13046-016-0487-8 (通讯作者)；
6. RongJun Mao, ZhiMing Jiang, HuiZhen Zhang, XiongZeng Zhu, QingLing Zhang（张庆玲）*. Clinical and pathological characteristics of giant cell angioblastoma: a case report. Diagnostic Pathology2012, 29;7:113. doi: 10.1186/1746-1596-7-113(通讯作者)；
7. Qingling Zhang（张庆玲）, Yu LiNa, Li Liu, Wang Shuang, YuFang Yang, Yi Ding, Jeevan Divakaran, Xin Li, YanQing Ding. LMP1 antagonizes WNT/β-catenin signalling through inhibition of WTX and promotes nasopharyngeal dysplasia but not tumourigenesis in LMP1B95−8 transgenic mice. J Pathology. 2011; 223: 574–583；
8. Qingling Zhang（张庆玲）, Shuang Wang, Jeevan Divakaran, Lina Yu, Yongjun Mao, Li Liu, Li He, Yongjian Den, YanQing. Malignant glomus tumor of the lung. Pathology. 2010, 42(6):594-596.；
9. Lin Zhang*, Siyuan Zhang*, Jun Yao , Frank J. Lowery, Qingling Zhang（张庆玲）, Wen-Chien Huang, Ping Li, Min Li, Xiao Wang, Chenyu Zhang, Hai Wang, Kenneth Ellis, Mujeeburahiman Cheerathodi, Joseph H. McCarty, Diane Palmieri, Jodi Saunus, Sunil Lakhani, Suyun Huang, Aysegul A. Sahin, Kenneth D. Aldape, Patricia S. Steeg, Dihua Yu. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature(2015); doi:10.1038/nature15376；
10. Jia Xu, Sunil Acharya, Ozgur Sahin, Qingling Zhang（张庆玲）, Saito,Yohei, Jun Yao, Hai Wang, Ping Li, Lin Zhang, Frank.J.Lowery , Wen-Ling Kuo, YiXiao, Joe Ensor, Aysegul A. Sahin, Xiang H.-F, Zhang, Mien-Chie Hung, Jitao David Zhang, AND Dihua Yu.14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.Cancer cell 2015 Feb;27(2): 177–192.
11. Ozgur Sahin, Qingfei Wang, Samuel W Brady, Kenneth Ellis, Hai Wang, Chia-Chi Chang, Qingling Zhang（张庆玲）, Preety Priya, Rui Zhu, Stephen T Wong, Melissa D Landis, William J Muller, Francisco J Esteva, Jenny Chang, Dihua Yu. Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors. Cell research 2014, 24 (5), 542-559.
