一、基本信息
姓名:郑燕芳
职称:主任医师
联系邮箱:18665000236@163.com
二、拟招收博士后开展的研究方向
1. 研究RNA结合蛋白(RBPs)在肿瘤发生、发展中的作用机制。
2. 研究功能未知的环状RNA在肺癌发生发展中的作用机制。
三、主要学术任职
中国生物医学工程学会肿瘤靶向治疗技术分会 候任主任委员;
广东省细胞生物学学会 常务副理事长、秘书长;
广东省抗癌协会生物治疗专业委员会 副主任委员;
广东省肿瘤靶向干预与防控学会 秘书长;
广东省基层医药学会中西医结合肿瘤专委会,副主任委员;
中国细胞生物学学会,理事;
广东省医学会肿瘤内科学分会,委员;
广东省医师协会肿瘤多学科诊疗模式工作委员会,委员;
广东省医院协会血栓与栓塞性疾病管理专业委员会,委员;
美国医学会、美国医师联合会 会员;
四、主要获奖情况
1. 2019年入选“广东医院最强科室之实力中青年医生”。
2. 2019年获评南方医科大学珠江医院首届“珠江青年医师奖”。
3. 2018年获评广东省杰出青年医学人才(第一批,广东省卫生计生委评审)。
4. 入选由广东省家庭医师协会推出的《2018年度岭南名医录》、《2019年度岭南名医录》。
5. 2017年在首届南粤好医生暨第三届羊城好医生评选活动中,获“羊城好医生”称号。
6. 2012年入选南方医科大学珠江医院优秀中青年人才库“学术带头人”层次人才。
五、代表性论文
1. He X#, Meng F#, Qin L, Liu Z, Zhu X, Yu Z, Zheng Y*. KLK11 suppresses cellular proliferation via inhibition of Wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma. American Journal of Cancer Research. 2019; Accepted on 2019-9-28. (*通讯作者,影响因子4.737)
2. Liu L, Cai S, Han C, Banerjee A, Wu D, Cui T, Xie G, Zhang J, Zhang X, Mclaughlin E, Yin M, Backes FJ, Chakravarti A, Zheng Y*, Wang QE*. ALDH1A1 contributes to PARP inhibitor resistance via enhancing DNA repair in BRCA2-/- ovarian cancer cells. Molecular Cancer Therapeutics. 2019; Published online on 2019-9-18. (*共同通讯作者,2区,影响因子4.856)
3. Wang Q#, Liu Z#, Du K, Liang M, Zhu X, Yu Z, Chen R, Qin L, Li Y, Zheng Y*. Babaodan capsule inhibits cell growth by inducing autophagy through the PI3K/AKT/mTOR pathway and enhances antitumor effects of cisplatin in non-small cell lung cancer cells. American Journal of Translational Research. 2019; 11(8): 5272-5283. (*通讯作者,影响因子3.266)
4. Liang M, Huang G, Liu Z, Wang Q, Yu Z, Liu Z, Lin H, Li M, Zhou X*, Zheng Y*. Elevated levels of hsa_circ_006100 in gastric cancer promote cell growth and metastasis via miR-195/GPRC5A signaling. Cell Proliferation. 2019; Jul 18:e12661. doi: 10.1111/cpr.12661. [Epub ahead of print]. (*通讯作者,2区,影响因子5.039)
5. Bi Y, Verginadis II, Dey S, Lin L, Guo L, Zheng Y*, Koumenis C*. Radiosensitization by the PARP inhibitor olaparib in BRCA1-proficient and deficient high-grade serous ovarian carcinomas. Gynecologic Oncology. 2018; 150(3): 534-544. (*共同通讯作者,2区,影响因子4.540)
6. Zhu X, Wang J, Li L, Deng L, Wang J, Liu L, Zeng R, Wang QE, Zheng Y*. GPX3 suppresses tumor migration and invasion via the FAK/AKT pathway in esophageal squamous cell carcinoma. American Journal of Translational Research. 2018;10(6): 1908-1920. (*通讯作者,影响因子3.266)
7. Wang J#, Xie W#, Liu F*, Bi Y, Zhu X, Wang Q, Zheng Y*. NADH protect against radiation enteritis by enhancing autophagy and inhibiting inflammation through PI3K/AKT pathway. American Journal of Translational Research. 2018; 10(6): 1713-1721. (*共同通讯作者,影响因子3.266)
8. Zeng R#, Liu Y#, Jiang Z#, Huang J, Wang Yu, Li X, Xiong W, Wu X, Zhang J, Wang QE, Zheng Y*. EPB41L3 is a potential tumor suppressor gene and prognostic indicator in esophageal squamous cell carcinoma. International Journal of Oncology. 2018; 52: 1443-1454. (*通讯作者,影响因子3.333)
9. Liu X#, Cheng X#, Wang F, Feng L, Wang Y,Zheng Y*, Guo R*. Targeted delivery of SNX-2112 by polysaccharide-modified graphene oxide nanocomposites for treatment of lung cancer. Carbohydrate Polymers. 2018; 185: 85-95. (*共同通讯作者,1区,影响因子4.811 )
10. Wang J#, Deng L#, Huang J, Cai R, Zhu X, Liu F, Wang Q, Zhang J*, Zheng Y*. High expression of Fibronectin 1 suppresses apoptosis through the NF-κB pathway and is associated with migration in nasopharyngeal carcinoma. American Journal of Translational Research. 2017; 9(10): 4502-4511. (*共同通讯作者,影响因子3.266)
11. Liu B, Sun T, Wu G, Shang-Guan H, Jiang Z, Zhang J*, Zheng Y*. MiR-15a suppresses hepatocarcinoma cell migration and invasion by directly targeting cMyb. American Journal of Translational Research. 2017; 9(2): 520-532. (*共同通讯作者,影响因子3.266)
12. Wu J, Zeng R, Huang J, Li X, Zhang J, Ho JC, Zheng Y*. Dietary Protein Sources and Incidence of Breast Cancer: A Dose-Response Meta-Analysis of Prospective Studies. Nutrients. 2016; 8(11). pii: E730. (*通讯作者,2区,影响因子3.550)
13. Zeng R, Huang J, Li X, Xiong W, Wu G, Jiang Z, Song S, Li J, Zheng Y*, Zhang J*. Epb41l3 suppresses esophageal squamous cell carcinoma invasion and inhibits MMP2 and MMP9 expression. Cell Biochem Funct. 2016; 34(3):133-141. (*共同通讯作者,影响因子2.186 )
14. Wu X, Zheng Y*, Tang M, Li X, Zeng R, Zhang J. Association between smoking and p53 mutation in oesophageal squamous cell carcinoma: a meta-analysis. Clinical Oncology. 2015; 27(6):337-44. (*通讯作者,影响因子3.398 )
15. Jiang Z, Song Q, Yang S, Zeng R, Li X, Jiang C, Ding W, Zhang J, Zheng Y*. Serum microRNA-218 is a potential biomarker for esophageal cancer. Cancer Biomarker. 2015; 15(4):381-9. (*通讯作者,影响因子1.736)
16. Song S, Walter V, Karaca M, Li Y, Bartlett CS, Smiraglia DJ, Serber D, Sproul CD, Plass C, Zhang J, Hayes DN, Zheng Y*, Weissman BE*. Gene Silencing Associated with SWI/SNF Complex Loss During NSCLC Development. Mol Cancer Res. 2014; 12 (4):560-70. (*共同通讯作者,2区,影响因子4.380)