一、基本信息
姓名：孙尔维
职称：教授
联系邮箱：sunew@smu.edu.cn
二、学习经历
1979.9-1984.7， 第二军医大学，军医系，学士
1984.9-1987.7， 第二军医大学，病理生理学，硕士
2005.9-2008.12，华中科技大学，器官移植，博士
三、拟招收博士后开展的研究方向
1.不同方式细胞坏死在自身免疫病中的致病作用
2.多靶点精准免疫疗法（NHMX）治疗系统性红斑狼疮的临床研究
3.调控DNA感受器活化在自身免疫病中的作用
4.抗原递呈细胞迁移在风湿免疫性疾病中的意义
四、主要学术任职
1. 中国免疫学会临床免疫分会副主任委员
2. 广东省免疫学会第五届理事会副理事长
3. 广东省免疫学会临床免疫学专业委员会主任委员
4. 广东省药学会风湿免疫用药专家委员会副主任委员
五、主要获奖情况
1.“羊城好医生”称号，2015
2. 南方医科大学第三附属医院先进个人，2015
3. 南方医科大学先进个人标兵，2013
4. 国家发明专利1项，2008
5. 第二临床医学院器官移植免疫研究所被评为南方医科大学本科生创新教育基地，2007
6. 南方医科大学先进个人标兵，2006
7. 《肾脏移植病历微机辅助管理系统》获优秀软件奖，1992
六、代表性论文
1. Yang F, Luo X, Luo G, Zhai Z, Zhuang J, He J, Han J, Zhang Y, Zhuang L, Sun E, He Y. Inhibition of NET formation by polydatin protects against collagen-induced arthritis. INTERNATIONAL IMMONOPHARMACOLOGY. 2019 (accepted)
2. Yang F, Zhai Z, Luo X, Luo G, Zhuang L, Zhang Y, Li Y, Sun E, He Y. Bioinformatics Identification of Key Candidate Genes and Pathways Associated with Systemic Lupus Erythematosus. CLINICAL RHEUMATOLOGY. 2019 (accepted)
3. Ji Y, He Y, Nian X, Sun E, Li L. Inflammatory or Neuropathic Pain: Characteristics and Their Relationships with Disease Activity and Functional Status in Axial Spondyloarthritis Patients. PAIN MEDICINE. 2019;20:882-8. doi: 10.1093/pm/pny138.
4. Nian X, He Y, Ji Y, Huang Y, Sun E, Li L. Associations Between Pain Patterns and Self-Reported Clinical Outcomes in Patients with Knee Osteoarthritis. PAIN MEDICINE. 2019;20:818-25. doi: 10.1093/pm/pny123.
5. Liao P, He Y, Yang F, Luo G, Zhuang J, Zhai Z, Zhuang L,Sun E. Polydatin effectively attenuates disease activity in lupus-prone mouse models by blocking ROS-mediated NET formation.ARTHRITIS RESEARCH & THERAPY. 2018;20. doi: 10.1186/s13075-018-1749-y.
6. He J, Li X, Zhuang J, Han J, Luo G, Yang F, Sun Y, Liao P, He Y, Shi H, Sun E. Blocking Matrix Metalloproteinase-9 Abrogates Collagen-Induced Arthritis via Inhibiting Dendritic Cell Migration. JOURNAL OF IMMUNOLOGY. 2018;201:3514-23. doi: 10.4049/jimmunol.1800412.
7. He Y, Yang F,Sun E.Neutrophil Extracellular Traps in Autoimmune Diseases. CHINESE MEDICAL JOURNAL. 2018;131:1513-9. doi: 10.4103/0366-6999.235122.
8. Huang X, He Y, Zhuang J, He J, Luo G, Han J,Sun E. Mycophenolic Acid Synergizing with Lipopolysaccharide to Induce Interleukin-1beta Release via Activation of Caspase-1. CHINESE MEDICAL JOURNAL. 2018;131:1533-40. doi: 10.4103/0366-6999.235116.
9. Han J, Zhou Q, Li X, He J, Han Y, Jie H, He Y,Sun E. Novel function of hydroxychloroquine: Down regulation of T follicular helper cells in collagen-induced arthritis. BIOMEDICINE & PHARMACOTHERAPY. 2018;97:838-43. doi: 10.1016/j.biopha.2017.10.132.
10. Shi H, He J, Li X, Han J, Wu R, Wang D, Yang F,Sun E. Isorhamnetin, the active constituent of a Chinese herb Hippophae rhamnoides L, is a potent suppressor of dendritic-cell maturation and trafficking. INTERNATIONALIMMUNOPHARMACOLOGY.2018;55:216-22. doi: 10.1016/j.intimp.2017.12.014.
11. Jie H, He Y, Huang X, Zhou Q, Han Y, Li X, Sun E. Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis. ONCOTARGET. 2016;7:19367-81. doi: 10.18632/oncotarget.8346.
12. Li X, Han Y, Zhou Q, Jie H, He Y, Han J, He J,Sun E. Apigenin, a potent suppressor of dendritic cell maturation and migration, protects against collagen-induced arthritis. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2016;20:170-80. doi: 10.1111/jcmm.12717.
13. Han Y, Li X, Zhou Q, Jie H, Lao X, Han J,Sun E. FTY720 Abrogates Collagen-Induced Arthritis by Hindering Dendritic Cell Migration to Local Lymph Nodes. JOURNAL OF IMMUNOLOGY. 2015;195:4126-35. doi: 10.4049/jimmunol.1401842.
14. He Y, Luo Y, Lao X, Tan L, Sun E. Experimental immunology Cytokine signatures of human whole blood for monitoring immunosuppression. CENTRAL EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;3:271-8. doi: 10.5114/ceji.2014.45936.
15. Sun E. The "Miracle" fetus: an excellent model for apoptotic cell-induced immune tolerance? FRONT BIOSCI. 2009;1:466-75.
16. Liu Z, Yuan X, Luo Y, He Y, Jiang Y, Chen Z,Sun E. Evaluating the effects of immunosuppressants on human immunity using cytokine profiles of whole blood. CYTOKINE. 2009;45:141-7. doi: 10.1016/j.cyto.2008.12.003.
17. Wang Y, Gao Y, Yuan X, Xia W, Luo Y, Sun E, Chen Z. The Liver Mediates Apoptotic Cell-Induced Immune Regulation. SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68:297-305. doi: 10.1111/j.1365-3083.2008.02141.x.
18.Li L, Liu Z,Chen J, Qian J,Sun E, Zhao M: Monitoring human leukocyte antigen humoral immunity sensitization in renal transplant recipients and its clinical significance. JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH 2008.
19. Li L, Chen J, Qian J, Li M,Sun E, Guo Y, Yue L, Fan L, Chen Ha, Zhao M:Correlation of human leucocyte antigen matching to acute rejection and allograft survival after renal allograft. JOURNAL OF CLINICAL REHABILITATIVE TISSUE ENGINEERING RESEARCH 2008.
20.Sun E. Cell death recognition model for the immune system. MEDICAL HYPOTHESES. 2008;70:585-96. doi: 10.1016/j.mehy.2007.05.049.
21. Feng Z, Sun E, Lan H, Zhang C, Li Q, Zhu W. Unrelated donor bone marrow transplantation for beta-thalassemia major: an experience from China. BONE MARROW TRANSPLANT 2006;37:171-4. doi: 10.1038/sj.bmt.1705193.
22. Shi Y, Roberts AI,Sun E.Dying T lymphocytes call for the death of tumor cells. CELL RESEARCH. 2006;16:679-80. doi: 10.1038/sj.cr.7310087.
23.Sun E, Gao Y, Chen J, Roberts AI, Wang X, Chen Z, Shi Y.Allograft tolerance induced by donor apoptotic lymphocytes requires phagocytosis in the recipient. CELL DEATH AND DIFFERENTIATION. 2004;11:1258-64. doi: 10.1038/sj.cdd.4401500.
24. Roberts AI, Devadas S, Zhang X, Zhang L, Keegan A, Greeneltch K, Sun E, Shi Y. The role of activation-induced cell death in the differentiation of T-helper-cell subsets. IMMUNOLOGIC RESEARCH. 2003;28:285-93. doi: 10.1385/IR:28:3:285.
25. Zhang L, Zhu T,Sun E, Shen SQ, Min ZL, Chen ZK. Pretreatment with FTY720 alone induced long-term survival of mouse heart allograft. TRANSPLANTATION PROCEEDINGS. 2003;35:567-8. doi: 10.1016/S0041-1345(02)03928-3.
26.Sun E, Shi Y. Apoptosis: the quiet death silences the immune system. Pharmacology and Therapeutics. 2001;92:135-45. doi: 10.1016/S0163-7258(01)00164-4.
27.Sun E, Zhang L, Zeng Y, Ge Q, Zhao M, Gao W. Apoptotic Cells Actively Inhibit the Expression of CD69 on Con A Activated T Lymphocytes. SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;51:231-6. doi: 10.1046/j.1365-3083.2000.00666.x.
28. Nakajima H, Sun E, Mizuta N, Fujiwara I, Oka T.FTY720 inhibits the mRNA expression of intragraft cytotoxic molecules, leading to cardiac allograft survival. TRANSPLANTATION PROCEEDINGS. 1998;30:2217-20. doi: 10.1016/S0041-1345(98)00595-8.
