一、基本信息

姓名：方唯意                                

职称：教授

联系邮箱：fangweiyi1975@163.com

 

二、学习经历

1993.9-1996.7  湖南医科大学，临床专业，大专

1999.9-2002.7  南华大学，药理学专业，硕士

2002.9-2005.7  中南大学，病理学与病理生理学专业，博士

 

三、拟招收博士后开展的研究方向

1. 肿瘤药理学（包括高分子材料药物、纳米材料药物、化学合成和天然中药等制备、疗效评价以及相关重要分子机理）

2. 肿瘤发病机理 

 

四、主要学术任职

1. 中国抗癌学会病因委员会，青委；

2. 中国抗癌学会肿瘤标志委员会，青委

 

五、代表性论文

1. Zhao M, Luo R, Liu Y, Gao L, Fu Z, Fu Q, Luo X, Chen Y, Deng X, Liang Z, Li X, Cheng C, Liu Z, Fang W.miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN.Nat Commun. 2016;7:11309(Corresponding author)；IF:12.124

2. Fu Q, Song X, Liu Z, Deng X, Luo R, Ge C, Li R, Li Z, Zhao M, Chen Y, Lin X, Zhang Q, Fang W.miRomics and Proteomics Reveal a miR-296-3p/PRKCA/FAK/Ras/c-Myc Feedback Loop Modulated by HDGF/DDX5/β-catenin Complex in Lung Adenocarcinoma.Clin Cancer Res. 2017;23(20):6336-6350. (Corresponding author)  IF:10.199

3. Deng X, Liu Z, Liu X, Fu Q, Deng T, Lu J, Liu Y, Liang Z, Jiang Q, Cheng C, Fang W.miR-296-3p Negatively Regulated by Nicotine Stimulates Cytoplasmic Translocation of c-Myc via MK2 to Suppress Chemotherapy Resistance.Mol Ther. 2018;26(4):1066-1081. IF:8.42

4. YongHao Li , Xiong Liu, Xian Lin, Menyang Zhao, Yanyi Xiao,Chen Liu, Zixi Liang， Zelong Lin，Renhui Yi，Zibo Tang, Jiahao Liu, Xin Li, Qingping Jiang, Zhen Liu,Weiyi Fang. Chemical compound Cinobufotalin potently induced FOXO1-stimulating Cisplatin sensitivity by antagonizing its-interactive protein MYH9. 2019, Accepted(Corresponding author).

5. Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X4, Cheng Z, Li L, Xie Y, Liu Z, Fang W.Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.EBioMedicine. 2019 Oct 5. [Epub ahead of print].(Corresponding author). IF:6.69