一、基本信息
姓名：周先举
职称：研究员，拟晋升副主任医师
联系邮箱：xianju_zhou@yahoo.com
二、学习经历
1989.9-1994.7 苏州医学院，临床医学专业，医学学士
1996.9-1999.7 苏州医学院，人体解剖学专业，医学硕士
2001.9-2005.7 中国科学院上海生命科学研究院神经科学研究所，神经生物学专业，理学博士
2005.12-2007.6 美国圣路易斯华盛顿大学医学院，神经科学博士后
2007.7-2010.6 美国密歇根州立大学生理科学系，神经科学博士后
三、拟招收博士后开展的研究方向
1. 重复经颅磁刺激治疗神经精神疾病的基础和临床；
2. 神经疾病的免疫和炎症机制；
3. 探索神经疾病的神经修复治疗手段。
四、主要学术任职
1. 中国康复学会帕金森病与运动障碍专委会，委员；
2. 江苏省重症康复专委会，委员；
3. 江苏省康复治疗专委会，委员。
五、主要获奖情况
1. 江苏省特聘医学专家，江苏省卫健委，2014；
2. 江苏省“六大高峰人才”，江苏省人力资源和社会保障厅，2014；
3.常州市医学重点学科神经病学学科带头人，常州市卫健委，2015；
4. 常州市卫生领军人才，常州市卫健委，2015；
5. 岭南名医，广东省家庭医生协会，2019。
六、代表性论文
1) Hongzhan Li, Jianqing Shang, Chengliang Zhang, Rulan Lu, Junpao Chen,Xianju Zhou*. Repetitive transcranial magnetic stimulation alleviates neurological deficits after cerebral ischemia through interaction between RACK1 and BDNFexon IV by the phosphorylation-dependent factor MeCP2. Neurotherapeutics, 2019, Accepted
2) Pengfei Cao, Linxiao Wang, Qi Cheng, Xiaojing Sun, , Qi Kang, , Libin Dai, Xianju Zhou*，Zixiang Song*, Changes in serum miRNA-let-7 level in children with attention deficit hyperactivity disorder treated by repetitive transcranial magnetic stimulation or atomoxetine. Psychiatry Research., 2019，274: 189-194.
3) Jie Feng#, Qing Zhang#, Chengliang Zhang, Zhongmin Wen, Xianju Zhou*.The Effect of low-frequency rTMS over bilateral dorsolateral prefrontal cortex on serum level of BDNF and GABA in patients with primary insomnia. Brain and Behavior. 2019, 9(2):e01206.
4) Rulan Lu, Chengliang Zhang, Yanyan Liu, Linxiao Wang, Xia Chen, Xianju Zhou*. The effect of bilateral low-frequency rTMS over dorsolateral prefrontal cortex on serum brain-derived neurotrophic and serotonin in patients with generalized anxiety disorder. Neuroscience Letters. 2018，684:67-71.
5) Linxiao Wang, Rulan Lu, Yanyan Liu, Guoying Dong, Xia Chen, Wenwei Yun, Xianju Zhou*. The role of S-nitrosylation of kainite-type ionotropic glutamate receptor 2 in epilepsy induced by kainic acid. Journal of Neurochemistry. 2018 ;144(3):255-270.
6) Yanyan Liu, Min Zhang, Yuan Chen, Ping Gao, Wenwei Yun*, Xianju Zhou*. The degree of leukoaraiosis predicts clinical outcomes and prognosis in patients with middle cerebral artery occlusion after intravenous thrombolysis. Brain Research. 2018, 1681:28-33.
7) Xianju Zhou*, Zhouyou Chen, Wenwei Yun and Hongbing Wang. Extrasynaptic NMDA receptor in excitotoxicity: Function revisted. Neuroscientist, 2015, 21(4)： 337 –344.
8) Zhuoyou Chen, Quan Zhou, Hongbing Wang, Weiwen Yun, Xianju Zhou*. Co-activation of synaptic and extrasynatpic NMDA receptors by neuronal insults determines cell death in acute brain slice. Neurochemistry International , 2014, 78：26-34.
9) Xianju Zhou*, Qi Ding, Zhuoyou Chen, Huifang Yun and Hongbing Wang. Involvement of GluN2A and GluN2B in synaptic and extrasynaptic NMDA receptor function and neuronal excitotoxicity. Journal of Biological Chemistry 2013, 288(33):24151-9.
10) Xianju Zhou*, Daniel Hollern, Jiayu Liao, Eran Andrechek, and Hongbing Wang. NMDA receptor-mediated excitotoxicity depends on co-activation of synaptic and extrasynaptic receptors. Cell Death and Disease 2013, 4:e560
