一、基本信息
姓名：杨志禄
职称：教授（四级岗），博士生导师
联系邮箱：zhiluyang1029@126.com
联系电话：13550075284
二、学习经历：
2001.09-2005.06，南昌航空大学，高分子材料与工程，学士
2005.09-2008.07，西南交通大学，材料物理与化学，硕士
2009.09-2014.07，西南交通大学，材料学，博士
三、拟招收博士后开展的研究方向：
1、心血管动脉粥样硬化病理发病机制研究
2、心血管疾病治疗的纳米靶向药物研究
3、药物球囊研究
4、具有病变血管组织再生修复及病灶治愈功能的冠脉、外周、颅内及下肢深静脉血管支架研究
5、心血管植入/介入器械及器官芯片研究
6、具有长效抗凝、抗感染和超润滑性功能的导管研究
7、可回收下腔静脉滤器研究
四、主要学术任职：
1、国际期刊Smart Materials in Medicine主编
2、国际期刊Research（Science第一本合作期刊）编委
3、国际期刊Bioactive Materials（IF=8.724）编委
4、国际期刊Bioactive Materials（IF=8.724）客座编辑
5、国际期刊Engineered Regeneration编委
6、中国生物材料学会医用金属材料分会委员
7、中国生物材料学会血液净化材料分会第一届委员
8、中国生物材料学会生物材料表界面工程分会第一届委员
9、中国生物材料学会康复器械与生物材料分会第一届常务委员
五、主要获奖情况：
1、四川省青年科技基金--杰出青年资助计划（项目号：2016JQ0027），四川省科技厅，2016年。
2、四川省学术和技术带头人后备人选，中共四川省委组织部、 四川省人力资源和社会保障厅、四川省发展和改革委员会、 四川省教育厅、 四川省科学技术厅、四川省财政厅、四川省科学技术协会、四川省科学界联合会，2018年。
六、代表性论文：
1. Qing Ma#, Xiuying Shi#, Xing Tan, Rui Wang, Kaiqin Xiong, Manfred F. Maitz, Yuanyuan Cui, Zhangmei Hu, Qiufen Tu*, Nan Huang, Li Shen*, Zhilu Yang*. Durable endothelium-mimicking coating for surface bioengineering cardiovascular stents. Bioactive Materials. 2021;12:4786-4800 (IF=8.724).
2. Han Yu#, Hua Qiu#, Wenmei Ma, Manfred F. Maitz, Qiufen Tu, Kaiqin Xiong, Jiang Chen*, Nan Huang*, Zhilu Yang*. Endothelium-Mimicking Surface Combats Thrombosis and Biofouling via Synergistic Long- and Short-Distance Defense Strategy. Small. 2021;2100729. (IF=11.459).
3. Wenxuan Wang#, Lei Lu#, Bei Ho Pan#, Xiangyang Li, Zeyu Du, Manfred F. Maitz, Qiufen Tu*, Nan Huang, Xin Zhao*, Zhilu Yang*. Self-protonating, plasma polymerized, superimposed multi-layered biomolecule nanoreservoir as blood-contacting surfaces. Chemical Engineering Journal. 2021;410:128313. (IF=10.652).
4. Hua Qiu, Qiufen Tu, Peng Gao, Xiangyang Li, Manfred F. Maitz, Kaiqin Xiong*, Nan Huang, Zhilu Yang*. Phenolic-amine chemistry mediated synergistic modification with polyphenols and thrombin inhibitor for combating the thrombosis and inflammation of cardiovascular stents. Biomaterials. 2021;269:120626 (IF=10.317).
5. Han Yu, Shaoxing Yu, Hua Qiu, Peng Gao, Yingzhong Chen, Xin Zhao, Qiufen Tu, Minggang Zhou*, Lin Cai, Nan Huang, Kaiqin Xiong*, Zhilu Yang*. Nitric oxide-generating compound and bio-clickable peptide mimic for synergistically tailoring surface anti-thrombogenic and anti-microbial dual-functions. Bioactive Materials. 2021;6:1618-1627 (IF=8.724).
6. Nan Lyu, Zeyu Du, Hua Qiu, Peng Gao, Qin Yao, Kaiqin Xiong, Qiufen Tu, Xiangyang Li, Binghai Chen, Guoqing Pan*, Nan Huang*, Zhilu Yang*. Mimicking the Nitric Oxide-Releasing and Glycocalyx Functions of Endothelium on Vascular Stent Surfaces. Advanced Science. 2020;7:202002330 (IF=15.84).
7. Zhilu Yang#, Xin Zhao#, Rui Hao, Qiufen Tu, Xiaohua Tian, Yu Xiao, Kaiqin Xiong, Miao Wang, Yonghai Feng, Nan Huang*, Guoqing Pan*. Bio-clickable and Mussel Adhesive Peptide Mimics for Engineering Vascular Stent Surfaces. PNAS. 2020;117:16127-16137 (IF=9.412).
8. Yu Xiao, Wenxuan Wang, Xiaohua Tian, Xing Tan, Tong Yang, Peng Gao, Kaiqing Xiong, Qiufen Tu, Miao Wang, Manfred F. Maitz, Nan Huang, Guoqing Pan*, Zhilu Yang*. A Versatile Surface Bioengineering Strategy Based on Mussel-Inspired and Bioclickable Peptide Mimic. Research. 2020;7236946.
9. Ying Yang, Peng Gao, Juan Wang, Qiufen Tu, Long Bai, Kaiqin Xiong, Hua Qiu, Xin Zhao, Manfred F. Maitz, Huaiyu Wang, Xiangyang Li, Qiang Zhao, Yin Xiao, Nan Huang*, Zhilu Yang*. Endothelium-Mimicking Multifunctional Coating Modified Cardiovascular Stents via a Stepwise Metal-Catechol-(Amine) Surface Engineering Strategy. Research. 2020;9203906.
10. Peng Gao, Hua Qiu, Kaiqin Xiong, Xiangyang Li, Qiufen Tu, Huaiyu Wang, Nan Lyu, Xiao Chen, Nan Huang*, Zhilu Yang*. Metal-Catechol-(Amine) Networks for Surface Synergistic Catalytic Modification: Therapeutic Gas Generation and Biomolecule Grafting. Biomaterials. 2020;248:119981 (IF=10.317).
11. Xiangyang Li#, Jingxia Liu#, Tong Yang, Hua Qiu, Lei Lu, Qiufen Tu, Kaiqing Xiong, Nan Huang*, Zhilu Yang*. Mussel-inspired “built-up” surface chemistry for combining nitric oxide catalytic and vascular cell selective properties. Biomaterials. 2020;241:119904 (IF=10.317).
12. Tong Yang, Zeyu Du, Hua Qiu, Peng Gao, Xin Zhao, Huaiyu Wang, Qiufen Tu, Kaiqin Xiong, Nan Huang, Zhilu Yang*. From surface to bulk modification: Plasma polymerization of amine-bearing coating by synergic strategy of biomolecule grafting and nitric oxide loading. Bioactive Materials. 2020;5:17-25 (IF=8.724).
13. Qiufen Tu#, Xin Zhao#, Shuai Liu, Xiangyang Li, Qiang Zhang, Han Yu, Kaiqin Xiong, Nan Huang, Zhilu Yang*. Spatiotemporal Dual-Delivery of Therapeutic Gas and Growth Factor for Prevention of Vascular Stent Thrombosis and Restenosis. Applied Materials Today. 2020;19:100546 (IF=8.352).
14. Hua Qiu#, Pengkai Qi#, Xing Tan, Yu Xiao, Jingxia Liu, Lei Lu, Peng Gao, Ying Yang, Nan Huang*, Zhilu Yang*. Biomimetic Engineering Endothelium-like Coating on Cardiovascular Stent through Heparin and Nitric Oxide-Generating Compound Synergic Modification Strategy. Biomaterials. 2019;207:10-22 (IF=10.317).
15. Feng Zhang#, Qiang Zhang#, Xiangyang Li, Nan Huang, Xin Zhao*, Zhilu Yang*. Mussel-inspired dopamine-CuII coatings for sustained in situ generation of nitric oxide for prevention of stent thrombosis and restenosis. Biomaterials. 2019;194:117-129 (IF=10.317).
16. Xiangyang Li, Peng Gao, Jianying Tan, Kaiqin Xiong, Changjiang Pan, Hongkai Wu, Yin Chen, Zhilu Yang*, Nan Huang*. Assembly of Metal-Phenolic/Catecholamine Networks for Synergistically Anti-Inflammatory, Antimicrobial and Anticoagulant Coatings. ACS Applied Materials & Interfaces. 2018;10:40844-40853 (IF=8.758).
17. Zhilu Yang*, Ying Yang, Kaiqin Xiong, Jin Wang, Haeshin Lee*, Nan Huang*, Metal-Phenolic Surfaces for Generating Therapeutic Nitric Oxide Gas. Chemistry of Materials. 2018;30:5220-5226 (IF=9.567).
18. Zhilu Yang*, Ying Yang, Li Zhang, Kaiqin Xiong, Xiangyang Li, Feng Zhang, Jin Wang, Xin Zhao*, Nan Huang*, Mussel-inspired Catalytic Selenocystamine-Dopamine Coatings for Long-Term Generation of Therapeutic Gas on Cardiovascular Stents. Biomaterials. 2018;178:1-10 (IF=10.317).
19. Xiangyang Li, Hua Qiu, Peng Gao, Ying Yang, Zhilu Yang*, Nan Huang*, Synergetic coordination- and catecholamine chemistry for catalytic generation of nitric oxide on vascular stents. NPG Asia Materials. 2018;10:482-496 (IF=8.131).
20. Ying Yang, Xiangyang Li, Hua Qiu, Ping Li, Manfred F. Maitz, Tianxue You, Ru Shen, Zhilu Yang*, Wenjie Tian*, and Nan Huang*. Polydopamine modified TiO2 nanotube arrays for long term controlled elution of bivalirudin and improved hemocompatibility. ACS Applied Materials & Interfaces. 2018;10:7649−7660 (IF=8.758).
21. Zhilu Yang*, Ying Yang, Kaiqin Xiong, Xiangyang Li, Pengkai Qi, Qiufen Tu, Fengjuan Jing, Yajun Weng, Jin Wang*, Nan Huang*. Nitric oxide producing coating mimicking endothelium function for multifunctional vascular stents. Biomaterials. 2015;63:80-92 (IF=10.317).
22. Zhilu Yang*, Kaiqin Xiong, Pengkai Qi, Ying Yang, Qiufen Tu, Jin Wang*, Nan Huang*. Gallic acid tailoring surface functionalities of plasma-polymerized allylamine-coated 316L SS to selectively direct vascular endothelial and smooth muscle cell fate for enhanced endothelialization. ACS Applied Materials & Interfaces. 2014;6:2647-2656 (IF=8.758).
23. Ying Yang, Pengkai Qi, Feng Wen, Xiangyang Li, Qin Xia, Manfred F. Maitz, Zhilu Yang*, Ru Shen, Qiufen Tu, Nan Huang*. Mussel-inspired one-step adherent coating rich in amine groups for covalent immobilization of heparin: hemocompatibility, growth behaviors of vascular cells and tissue response. ACS Applied Materials & Interfaces. 2014;6:14608-14620 (IF=8.758).
24. Zhilu Yang#,*, Ying Yang#, Wei Yan, Qiufen Tu*, Jin Wang*, Nan Huang. Construction of polyfunctional coatings assisted by gallic acid to facilitate co-immobilization of diverse biomolecules. ACS Applied Materials & Interfaces. 2013;5:10495-10501 (IF=8.758).
25. Zhilu Yang, Qiufen Tu*, Manfred F. Maitz, Shou Zhou, Jin Wang, Nan Huang*. Direct thrombin inhibitor-bivalirudin functionalized plasma polymerized allylamine coating for improved biocompatibility of vascular devices. Biomaterials. 2012;33:7959-7971 (IF=10.317).
26. Zhilu Yang*, Qiufen Tu, Jin Wang*, Nan Huang*. The role of heparin binding surface in the direction of endothelial and smooth muscle cell fate and re-endothelialization. Biomaterials. 2012;33:6615-6625 (IF=10.317).
27. Zhilu Yang, Jin Wang*, Rifang Luo, Manfred F. Maitz, Fengjuan Jing, Hong Sun, Nan Huang. The covalent immobilization of heparin to pulsed-plasma polymeric allylamine films on 316L stainless steel and the resulting effects on hemocompatibility. Biomaterials. 2010;31:2072–2083 (IF=10.317).
