一、基本信息
姓名:江建新
职称:主任医师
联系邮箱:rm002979@whu.edu.cn
二、学习经历
1992.09-1995.07 三峡大学医学院医学系学习。
2001.09-2004.07 贵阳医学院,硕士学历,硕士学位。
2006.09-2009.07 华中科技大学同济医学院,博士学历,博士学位。
三、拟招收博士后开展的研究方向
1. 胰腺癌侵袭转移的分子机制研究。
2. 胰腺癌相关转化医学研究。
3. 新型材料在抗肿瘤中的应用。
四、主要学术任职:
1. 中华医学会外科学分会第十六、十七、十八届中青年委员
2. 中华医学会外科学分会第十七胰腺外科组委员
3. 中国医疗保健国际交流促进会(医促会)胰腺疾病分会委员
4. 中国医疗保健国际交流促进会(医促会)胰腺疾病分会,胰腺疾病微创治疗学组委员
5. 中国研究型医院学会胰腺疾病专业委员会委员
6. 中国研究型医院学会胰腺疾病专业委员会微创胰腺治疗学组委员
7. 中国医师协会胰腺癌专业委员会委员
8. 中国医师协会外科医师分会加速康复外科委员会
9. 中国医学装备协会基础装备分会委员
10.中国抗癌协会肿瘤标志专业委员会非编码 RNA 与肿瘤研究专委会常委
五、主要获奖情况
1.腹腔镜、胆道镜及十二指肠镜“三镜”联合及术中激光碎石在胆道结石治疗中的应用, 一等奖,恩德思医学科学技术奖评奖委员会, 2012 年,排名第 2.
六、代表性论文:
1. He Z, Wang J, Xu J, Jiang X, Liu X, Jiang J. Dynamic regulation of KIF15 phosphorylation and acetylation promotes focal adhesions disassembly in pancreatic cancer. Cell death & disease 2022, 13(10): 896.
2. Wang J, He Z, Xu J, Chen P, Jiang J. Long noncoding RNA LINC00941 promotes pancreatic cancer progression by competitively binding miR-335-5p to regulate ROCK1-mediated LIMK1/Cofilin-1 signaling. Cell death & disease 2021, 12(1): 36.
3. Lei S, He Z, Chen T, Guo X, Zeng Z, Shen Y, Jiang J. Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway. Journal of Experimental & Clinical Cancer Research : CR 2019, 38(1): 470.
4. Xu J, Wang J, He Z, Chen P, Jiang X, Chen Y, Liu X, Jiang J. LncRNA CERS6-AS1 promotes proliferation and metastasis through the upregulation of YWHAG and activation of ERK signaling in pancreatic cancer. Cell death & disease 2021, 12(7): 648.
5. Wang J, He Z, Liu X, Xu J, Jiang X, Quan G, Jiang J. LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2. Cell death & disease 2022, 13(8): 718.
6. Chen P, He Z, Wang J, Xu J, Jiang X, Chen Y, Liu X, Jiang J. Hypoxia-Induced ZWINT Mediates Pancreatic Cancer Proliferation by Interacting With p53/p21. Frontiers In Cell and Developmental Biology 2021, 9: 682131.
7. He Z, Wang J, Zhu C, Xu J, Chen P, Jiang X, Chen Y, Jiang J, Sun C. Exosome-derived FGD5-AS1 promotes tumor-associated macrophage M2 polarization-mediated pancreatic cancer cell proliferation and metastasis. Cancer letters 2022, 548: 215751.
8. Zeng Z, Lei S, He Z, Chen T, Jiang J. YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration. J Cell Physiol 2021, 236(3): 2087-2098.
9. Liu T, Zhou L, He Z, Chen Y, Jiang X, Xu J, Jiang J. Circular RNA hsa_circ_0006117 Facilitates Pancreatic Cancer Progression by Regulating the miR-96-5p/KRAS/MAPK Signaling Pathway. J Oncol 2021, 2021: 9213205.
10. Chen Y, Xu S, Liu X, Jiang X, Jiang J. CircSEC24A upregulates TGFBR2 expression to accelerate pancreatic cancer proliferation and migration via sponging to miR-606. Cancer Cell International 2021, 21(1): 671.
11. Liu X, Zhou L, Chen Y, Jiang X, Jiang J. CircRNF13 Promotes the Malignant Progression of Pancreatic Cancer through Targeting miR-139-5p/IGF1R Axis. J Oncol 2021, 2021: 6945046.
12. Jiang X, Wang J, Chen P, He Z, Xu J, Chen Y, Liu X, Jiang J. [6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling. Cancer Cell International 2021, 21(1): 420.
13. Jiang J, Li Z, Yu C, Chen M, Tian S, Sun C. MiR-1181 inhibits stem cell-like phenotypes and suppresses SOX2 and STAT3 in human pancreatic cancer. Cancer letters 2015, 356(2 Pt B): 962-970.
14. Zhang D, He Z, Shen Y, Wang J, Liu T, Jiang J. MiR-489-3p Reduced Pancreatic Cancer Proliferation and Metastasis By Targeting PKM2 and LDHA Involving Glycolysis. Frontiers In Oncology 2021, 11: 651535.
15. He Z, Guo X, Tian S, Zhu C, Chen S, Yu C, Jiang J, Sun C. MicroRNA-137 reduces stemness features of pancreatic cancer cells by targeting KLF12. Journal of Experimental & Clinical Cancer Research : CR 2019, 38(1): 126.
16. Lei S, He Z, Chen T, Guo X, Zeng Z, Shen Y, Jiang J. Long noncoding RNA 00976 promotes pancreatic cancer progression through OTUD7B by sponging miR-137 involving EGFR/MAPK pathway. Journal of Experimental & Clinical Cancer Research : CR 2019, 38(1): 470.
17. Wang J, Guo X, Xie C, Jiang J. KIF15 promotes pancreatic cancer proliferation via the MEK-ERK signalling pathway. British Journal of Cancer 2017, 117(2): 245-255.
18. Chen P, He Z, Wang J, Xu J, Jiang X, Chen Y, Liu X, Jiang J. Hypoxia-Induced ZWINT Mediates Pancreatic Cancer Proliferation by Interacting With p53/p21. Frontiers In Cell and Developmental Biology 2021, 9: 682131.
19. Zhou X, Guo X, Chen M, Xie C, Jiang J. HIF-3α Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC-ROCK1 Signaling Pathway. Mol Cancer Res 2018, 16(1): 124-134.