职称:讲师,博士
联系方式:南方医科大学药学院
Email: jinhong@smu.edu.cn
工作经历:
2001.09-至今南方医科大学药学院,讲师
1995.07-1998.06南方医科大学基础医学院组织胚胎学教研室,讲师
1989.07-1992.06 湖北崇阳县沙坪镇医院,全科医师
学习经历:
1998.09-2001.07 第一军医大学药理学 医学博士学位
1992.09-1995.07 中山医科大学组织胚胎学 医学硕士学位
1984.09-1989.07 湖北医学院 医疗专业 医学学士学位
承担课程:
《药理学》
科研课题:
1. 广东省卫生厅微生物来源的抗阿尔茨海默氏病乙酰胆碱酯酶抑制剂的研究,项目负责人。
2.广东省自然科学基金研究团队项目,微生物来源的新型医用和农用乙酰胆碱酯酶抑制剂的研究,核心成员之一。
3. 国家自然科学基金面上项目,基于酵母RNA三杂交的高通量端粒酶特异抑制剂筛选模型的建立及其应用,2007.01---2009.12,排名二。
主要论著:
1.Zhou D, Jin H, Lin HB, Yang XM , Cheng YF, Deng FJ, Xu JP. Antidepressant effect of the extracts from Fructus Akebiae.Pharmacology Biochemistry and Behavior 2010,94(3):488-495
2. Hong Jin, Zheng-Guang Zhu, Peng-Jiu Yu, Guang-Fa Wang, Jun-Yan Zhang, Jing-Rong Li,Rui-Ting Ai, Zhong-Huang Li, Yuan-Xin Tian, Wei Xu,Jia-Jie Zhang and Shu-Guang Wu.Myrislignan Attenuates Lipopolysaccharide-induced Inflammation Reaction in Murine Macrophage Cells Through Inhibition of NF-kB Signalling Pathway Activation.Phytother. Res. (2012) Published online in Wiley Online Library (wileyonlinelibrary.com) DOI: 10.1002/ptr.3707
3. Peng-Jiu Yu, Hong Jin, Jun-Yan Zhang, Guang-Fa Wang, Jing-Rong Li,Zheng-Guang Zhu, Yuan-Xin Tian, Shao-Yu Wu, Wei Xu, Jia-Jie Zhang,and Shu-Guang Wu. Pyranocoumarins Isolated from Peucedanum praeruptorum Dunn Suppress Lipopolysaccharide-Induced Inflammatory Response in Murine Macrophages Through Inhibition of NF-κB and STAT3 Activation. Inflammation (2011) DOI: 10.1007/s10753-011-9400-y.
4. Zhang JY, Jin H, Wang GF, Yu PJ, Wu SY, Zhu ZG, Li ZH, Tian YX, Xu W, Zhang JJ, Wu SG. Methyl-1-hydroxy-2-naphthoate, a novel naphthol derivative, inhibits lipopolysaccharide-induced inflammatory response in macrophages via suppression of NF-kB, JNK and p38 MAPK pathways. Inflamm Res. 2011 Sep; 60(9):851-9.
5. Yu PJ, Ci W, Wang GF, Zhang JY, Wu SY, Xu W, Jin H, Zhu ZG, Zhang JJ, Pang JX, Wu SG.Praeruptorin a inhibits lipopolysaccharide-induced inflammatory response in murine macrophages through inhibition of NF-κB pathway activation. Phytother Res. 2011 Apr; 25(4):550-6.
6.Wang GF, Wu SY, Xu W, Jin H, Zhu ZG, Li ZH, Tian YX,Zhang JJ, Rao JJ, Wu SG. Geniposide inhibits high glucose-induced cell adhesion through the NF-kappa B signaling pathway in human umbilical vein endothelial cells.Acta Pharmacol Sin. 2010. 31(8):953-62.
7. Li L, Tan S, Lu H, Lu L, Yang J, Jin H, Liu S, Jiang S. Combinations of 3-Hydroxyphthalic Anhydride- modified Ovalbumin with Antiretroviral Drug-based Microbicide Candidates Display Synergistic and Complementary Effects against HIV-1 Infection.J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):384-92.
8. Yang J, Li L, Tan S, Jin H, Qiu J, Mao Q, Li R, Xia C, Jiang ZH, Jiang S, Liu S.A natural theaflavins preparation inhibits HIV-1 infection by targeting the entry step: Potential applications for preventing HIV-1 infection. Fitoterapia.2012 Mar; 83(2):348-55.
9. 石光,庞建新,孔焕育,罗超,刘霭明,金宏,曹莹. 尖吻蝮蛇血凝酶药效评价及其作用机制.中国新药杂志,2010,19(18): 1706-1709
专利:
1. 张嘉杰,金宏,田元新,朱正光,李中皇,王广发,万山河,叶连宝,游文玮,吴曙光。一种螺三环类化合物及其制备方法、以含该类化合物的药物组合物及其应用。2012,中国,申请公开号:CN 102516263A
2. 张嘉杰, 朱正光,李中皇,王广发,金宏,田元新,万山河,叶连宝,游文玮,吴曙光。一种稠三环类化合物及其制备方法、以含该类化合物的药物组合物及其应用。2012,中国,申请公开号:CN 1025039593A