饶进军
职称:副教授
联系邮箱:raojj@smu.edu.cn
联系电话:020-61648535
学习经历:
1998/09—2001/07 第一军医大学研究生队,药理学博士
1993/09—1995/07 第一军医大学研究生队,药理学硕士
1981/09—1986/06 第一军医大学军医系,学士
工作经历:
2004/08—至今 南方医科大学药学院,副教授
2001/09—2004/08 第一军医大学分校,副教授
1986/08—1998/08 解放军广州军区军医学校,教员
研究方向:
1.肿瘤药理学
2.临床药理学
主要学术任职:
1.广东省临床药理学专业委员会常务委员
2.广东省药物经济学专业委员会常务委员
3.广东省抗炎免疫专业委员会常务委员
获奖情况
1.军队科技进步奖三等奖;解放军总后勤部,1995;
2.中国药理学会周金黄优秀青年论文二等奖,中国药理学会,1995;
3.广东省大中专学生“三下乡”活动先进个人,广东省委宣传部,2008。
教学课题:
广东省高等教育教学改革项目:“五年制临床药学专业实践教学改革与探索”; 2018-2020.
承担科研课题:
1.广东省-教育部产学研结合项目:以PcG蛋白为靶点逆转肿瘤多药耐药RNA干扰药物的研发(2012B091100465),2012.10-2017.10;
2.广东省自然科学基金:PcG蛋白做为抗肿瘤新靶点的机制研究(S2012010009368),2012-2014;
3.广东省-教育部产学研结合项目:组蛋白去乙酰化酶抑制剂逆转肿瘤多药耐药性的应用开发研究(2009B090300282),2010.01-2012.12;
4.广州市科技支撑项目:肺癌新型多药耐药逆转剂丙戊酸钠的临床前研究(2010GN-E00221,2011.01-2013.12;
5.广东省科技计划项目:广东省药品阳光采购工程的药学评估及其信息资源的开发应用(2008B030303016),2008-2011;
6.广东省科技计划项目:“生物医药产业创新创业人才药学培训体系的建立与实践”(2015A070712005),2015-2020;
7.广东省组织工程重点实验室项目:PCG蛋白在调节组织修复中的作用研究;2019-2021。
代表性论文:
1.Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors.Qiu L,Xie EJ,Zhiru C,Lin C,Xian-Sen H,Zi-Hua L,Wen-Wei Y,Jin-Jun R*,Pei-Liang Z*,.Bioorg Chem. 2020 Sep 102(1):104-46.
2.Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.Yang F, He CP, Diao PC, Hong KH,Rao JJ*, Zhao PL*.Boorg Med Chem Lett.2019 Jan 1; 29(1):22-27.
3.Protective role of 6-Hydroxy-1-H-Indazole in an MPTP-induced mouse model of Parkinson's disease.Xiao-Feng L, Wen-Ting Z, Yuan-Yuan X, Chong-Fa L, Lu Z,Jin-Jun R*,Wen-Ya W*. Eur J Pharmacol. 2016 Nov 15; 791:348-354.
4.Ma H, Wu Z, Peng J, Li Y, Huang H, Liao Y, Zhou M, Sun L, Huang N, Shi M, Bin J, Liao Y,Rao J, Wang L, Liao W.Inhibition of SLC1A5 sensitizes colorectal cancer to cetuximab.
Int J Cancer. 2018 Jun 15;142(12):2578-2588.
5.Zhang S, Liu Y, Derakhshanfar S, He W, Huang Q, Dong S,Rao J, Luo GX, Zhong W, Liao W, Shi M, Xing M.Polymer Self-Assembled BMSCs with Cancer Tropism and Programmed Homing.Adv Healthc Mater. 2018 Dec;7(23): e1800118.
6.Huang Z, Liu Y, Yang C, Li X, Pan C,Rao J, Li N, Liao W, Lin L.Combined neutrophil/platelet/lymphocyte/differentiation score predicts chemosensitivity in advanced gastric cancer.BMC Cancer.2018 May 2;18(1):515.
7.Zhao Y, Liu Y, Lin L, Huang Q, He W, Zhang S, Dong S, Wen Z,Rao J, Liao W, Shi M.The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1.Mol Cancer. 2018 Mar 6;17(1):69
8.Zeng D, Li M, Zhou R, Zhang J, Sun H, Shi M, Bin J, Liao Y,Rao J, Liao W.Tumor Microenvironment Characterization in Gastric Cancer Identifies Prognostic and Immunotherapeutically Relevant Gene Signatures.Cancer Immunol Res. 2019 May;7(5):737-750.
9.Hao S, Yu J, He W, Huang Q, Zhao Y, Liang B, Zhang S, Wen Z, Dong S,Rao J, Liao W, Shi M.Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells.Neoplasia. 2017 Dec;19(12):1022-1032.
10.Zhang G, Yang G, Deng Y, Zhao X, Yang Y,Rao J, Wang W, Liu X, He J, Lv L.Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode.BMC Complement Altern Med. 2016 Feb 6;16:56.
11.Wang GF, Wu SY, Xu W, Jin H, Zhu ZG, Li ZH, Tian YX, Zhang JJ,Rao JJ*, Wu SG*;Genniposide inhibits high glucose-induced cell adhesion through the NF-kappaB signaling pathway in human umbilical vein endothelial cells.Acta Pharm Sin. Aug;31(8):953-6,2010.
12.Lin Lv, Shao-Yu Wu, Guang-Fa Wang, Jia-Jie Zhang,Jian-Xin Pang, Zhong-Qiu Liu, Wei Xu, Shu-Guang Wu*,Jin-Jun Rao*; Effect of Astragaloside IV on Hepatic Glucose-regulating Enzymes in Diabetic Mice Induced by a High-fat Diet and Streptozotocin;Phyto Res, 24(2)219-224,2010.
13.Shao-yu Wu, Guang-fa Wang, Zhong-qiu Liu,Jin-jun Rao, Lin Lv, Wei Xu, Shu-guang Wu and Jia-jie Zhang. Effect of geniposide, a hypoglycemic glucoside, on hepatic regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin. Acta Pharm Sin;2009,30: 202–208.
14.Guang-fa Wang, Shao-yu Wu,Jin-jun Rao, Lin Lv, Wei Xu, Jian-xin Pang, Zhong-qiu Liu, Shu-guang Wu, Jia-jie Zhang. Genipin inhibits endothelial exocytosis via nitric oxide in cultured human umbilical vein endothelial cells.Acta Pharm Sin,2009,30(5):589-596.
专利:
1.饶进军,陈云燕,王新波,吴少瑜,吕琳,王文雅,杨迎暴;丙戊酸在制备抗肿瘤多药耐药逆转剂中的应用;2013.01,中国,201310009693.6。
2.饶进军王旦旦钟晶晶杨旭锐麦梅清何彩萍;一种抑制RbAp48的基因的siRNA及其抗肿瘤应用(201711329890.0)。
3.饶进军何彩萍杨旭锐钟晶晶麦梅清何关生王旦旦毛楠;抑制RbAp48基因的siRNA在制备抗肿瘤化疗药物增敏剂中的应用(201711331633.0)。
4.吴少瑜;文晓芸;姜志宏;刘中秋;张嘉杰;饶进军;王广发;徐伟;吕琳;吴曙光。1,3,4-三-O-没食子酰基-6-O-咖啡酰基-β-D-吡喃葡萄糖在制备抗肿瘤药物中的应用,200710030596.X。
5.王广发;吴少瑜;张嘉杰;饶进军;徐伟;吕琳;吴曙光。一种新的蛇毒多肽及其制备方法和应用,200810029548.3。
6.文晓芸;吴少瑜;姜志宏;刘中秋;张嘉杰;饶进军;王广发;徐伟;吕琳;吴曙光。1,3-二-O-没食子酰基1-4,6-(S)-HHDP-β-D-吡喃葡萄糖在制备抗肿瘤药物中的应用,200710030597.4。
编写教材/专著:
1.《抗炎免疫药理学》;人民卫生出版社,ISBN:9787117064897;编委。
2.《临床药理与药物治疗学》;校内教材,主编。