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刘利红



姓名:刘利红

职称:教授,博士生导师

联系邮箱:lhliu02@126.com

联系电话:020-61648595


 

学习经历:

1995.09-1999.07  河北科技大学, 染整工程, 学士

2002.09-2007.06  兰州大学,分析化学,博士

2013.12-2014.12  美国麻省理工学院, 电子工程系,访问学者

2018.01-2018.03  新加坡-麻省理工学院科研中心(SMART),访问学者


 

工作经历:

2007.07-2010.12  南方医科大学药学院,讲师

2010.12-2015.12  南方医科大学药学院,副教授

2015.12-至今     南方医科大学药学院,教授


 

承担课程:

《分析化学》,《仪器分析》


 

研究方向:

1. 药物分析及筛选新方法的研究及应用。

2. 微流控芯片在临床用药及疾病诊断中的研究应用。

3. 纳米材料在临床诊断中的研究


 

承担的课题:

1.基于集成微流控芯片的血小板功能检测新方法研究(81973282),国家自然科学基金面上项目,55万,2020.01-2023.12,主持

2.毛细管电泳柱端GNPas-Ap-Ber微反应器间接超灵敏检测CRP新方法的研究(2018A030313843), 广东省科技创新战略专项资金,2018.05-2021.04,主持

3.基于微流控芯片在线检测生物药中内毒素含量的新方法研究,广东省科技计划项目(协同创新与平台环境建设(2016A040403052, 2016.01-2018.12主持

4.基于微流控芯片在线检测全血中内毒素的新方法研究(81470161),国家自然科学基金面上项目,2015/01~2016/12,主持

5.N/C-多肽与纳米金层层自组装微反应器在HIV gp41抑制剂筛选中的应用(2012045),广州市珠江科技新星专项,2012/07~2015/07主持

6.基于毛细管电泳柱端微反应器筛选HIV gp41融合抑制剂的研究(30901826),国家自然科学基金青年项目,2010/01~2012/12主持


 

代表论文: 

1. Niu, J.X., Hu X.M., Ouyang W., Chen Y., Liu S.W., Han J.Y. *, and Lihong Liu*, 2019. Femtomolar Detection of Lipopolysaccharide in Injectables and Serum Samples Using Aptamer-Coupled Reduced Graphene Oxide in a Continuous Injection-Electrostacking Biochip. Analytical Chemistry, 2019, 91, 3, 2360-2367. 

2. Liu, Z., Hettihewa, M., Shu, Y., Zhou, C., Wan, Q., & Liu Lihong*, 2018. The mechanism of the adsorption of dsdna on citrate-stabilized gold nanoparticles and a colorimetric and visual method for detecting the v600e point mutation of the braf gene. Microchimica Acta, 185(4), 240. 

3. Xu, X.X., Li, L., Liu, Z., X.J. Yao, Zhang, X.X., Liu, S.W.*, Liu, Lihong*, 2018. Investigation of the inhibition effect of arachidonic acid on the corestructure of the HIV-1 gp41, Journal of Pharmaceutical and Biomedical Analysis 161:377-382.

4. Liu Lihong *, Wan, Q, Xu, X.Y., Duan, S.S, Yang, C.L., 2017, Combination of micelle collapse and field-amplified sample stacking in capillary electrophoresis for determination of trimethoprim and sulfamethoxazole in animal-originated foodstuffs. Food Chemistry, 219: 7-12.

5. Wan Q, Liu Y, Yang C, Liu Lihong *. 2017, On-line double focusing of atenolol and metoprolol in human urine using capillary electrophoresis with the aid of β-cyclodextrin[J]. Analytica Chimica Acta, 978:61-67.

6. Lihong Liu, S. Huang., X.Y. Xu J.Y. Han, Study of Individual erythrocyte deformability susceptibility to INFeD and ethanol using a microfluidic chip. Scientific Reports, 2016, 6, 22929; doi: 10.1038/srep22929.

7. Liu, Lihong, Xu, X.X., Liu, Y.H., Zhang, X.X., Li, L., Jia, Z.M., Screening HIV-1 fusion inhibitors based on capillary electrophoresis head-end microreactor targeting to the core structure of gp41.  Journal of Pharmaceutical and Biomedical Analysis 2016, 120: 153-157. (IF2014 = 2.979)

8. Xu, X.Y., Jia, Z.M., Shu, Y., Liu, Lihong*, Dynamic pH junction-sweeping technique for on-line concentration of acidic amino acids in human serum by capillary electrophoresis with indirect UV detection. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Science , 2015, 980: 20-27. IF 2.694

9. Xu, X.Y.,Liu, Lihong*Jia, Z.M.,Shu, Y., Determination of enrofloxacin and ciprofloxacin in foods of animal origin by capillary electrophoresis with field amplified sample stacking-sweeping technique. Food Chemistry, 2015, 176: 219-225. IF 3.259

10. Shu, Y., Xue, W.W., Xu, X.Y., Jia, Z.M., Yao, X.J., Liu, S.W., Liu, Lihong*, Interaction of erucic acid with bovine serum albumin using a multi-spectroscopic method and molecular docking technique. Food Chemistry 2015, 173: 31-37. IF 3.259

11.Liu, Lihong*,You W.W. Zheng, L.J., Chen, F. Y, Jia, Z.M., Determination of peimine and peiminine in Bulbus Fritillariae Thunbergii by capillary electrophoresis by indirect UV detection using N-(1-naphthyl)ethylenediamine dihydrochloride as probe. Electrophoresis 2012, 33: 2152-2158. IF 3.161

12. Liu, Lihong*, Deng, X.X., Chen, X.G., Micelle to trapping solution stacking in micellar electrokinetic chromatography. Journal of Chromatography A, 2010, 1217: 175-178. IF 4.258

13. Liu, Lihong*, Chen, X.G., Liu, J.L., Deng, X.X., Duan, W.J., Tan, S.Y., Determination of capsaicin and dihydrocapsaicin in Capsicum anuum and related products by capillary electrophoresis with a mixed surfactant system. Food Chemistry 2010, 119: 1228-1232. IF 3.259


文章列表见:http://www.researcherid.com/rid/F-1512-2010 

 

专利情况:

1、刘利红,牛俊心,一种检测内毒素的方法,专利申请号:201811061693.X。

2、刘利红,刘贞,一种基于微流控芯片检测己酮可可碱对冠心病患者红细胞变形能力及生物化学指标的影响,专利申请号:201810144124.5。

3、刘利红,刘贞,己酮可可碱对蛋白激酶C的抑制作用及其应用,专利申请号:201810915533.0。

4、刘利红,刘贞,体外检测脂多糖对红细胞变形能力影响的方法及应用,专利申请号:201810466533.7。

5、刘利红,徐小英,李琳,张萱萱,花生四烯酸在制备抗HIV疫苗或药物中的应用,中华人民共和国国家知识产权局,201410339752.0(已授权)。

6、刘利红,徐小英,李琳,张萱萱,一种抗HIV中药的有效部位及其制备方法,中华人民共和国国家知识产权局,201410166156.7(已授权)。

7、刘利红,舒阳,基于未修饰纳米金与双链DNA相互作用的比色法检测DNA,中华人民共和国国家知识产权局,ZL 201510590912.3(已授权)

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