[已阅读次]
陈建军

姓名:陈建军
职称:教授(三级岗),博士生导师
联系邮箱:jchen21@smu.edu.cn
联系电话:

学习经历:
1.1998.9-2003.7    沈阳药科大学 ,药学(英语),学士
2.2004.5-2006.5    韩国江原国立大学,药物化学,硕士
3.2006.8-2011.5    美国田纳西大学,药物化学,博士
4.2011.5-2013.12   美国田纳西大学,博士后

工作经历:
1.2003.7-2004.5    中国中化集团青岛公司,医药外贸与技术助理

2.2006.8-2011.5    美国田纳西大学,研究助理

3.2014.1-2015.8    美国南方大学药学院,助理教授 (Assistant Professor)

4.2015.8-2017.8    美国芝加哥州立大学药学院,助理/副教授 (Assistant/Associate Professor)

5.2017.8-          南方医科大学药学院,教授

研究方向:
1.新型抗癌小分子药物的合成及体内外活性研究

2.新药筛选/研发,计算机辅助药物设计,合成药物化学

主要学术任职:
1.美国制药科学家协会(AAPS)  会员

2.美国药学院联合会(AACP) 会员

3.美国癌症协会(AACR) 会员

4.美国化学会(ACS) 会员

主要获奖情况:

1.“New Investigator Award”,美国药学院联合会/AACP, 2016

2.“Distinguished Scholar of the Year”, 美国南方大学药学院, 2015

3.“Travel award”,美国田纳西大学, 2011

4.“Travel award”,泛美色素细胞研究学会会员/PASPCR, 2009

5.“BEST-KNU fellowship” 韩国江原国立大学, 2004

主要科研课题:
1. 广东省高水平大学建设/ 南方医科大学高层次人才引进科研启动项目。主持人 (PI)。

2. 美国国立卫生研究院/NIH/NIGMS, SC3, 1SC3GM122599。 Novel HIF1α Inhibitors for the Treatment of Breast Cancer。 2016.8-2019.7。 经费总额: 36万美金。 主持人 (PI)。

3. 美国药学院联合会/AACP。 New Investigator Award。 Novel & Targeted Prodrug Strategy For The Treatment of Resistant Ovarian Cancer。2016.1-2016.12。 经费总额: 1万美金。主持人(PI)。

4. 美国国立卫生研究院/NIH, 1S10OD016226-01A1,Mass Spectrometer for Small Molecule Drug Development。 2014.1-2014.12。 经费总额: 30万美金。 合作研究者 (Co-I)。

5. 美国国立卫生研究院/NIH, 1S10OD010678-01,Acquisition of a Q-TOF Mass Spectrometer。2012.5-2013.4。 经费总额: 32万美金。 合作研究者 (Co-I)。

6. 美国田纳西大学 Technology Maturation Award。Preclinical studies of new vitamin D analogs as potential agents for arthritis。1/2011-10/2011。经费总额: 1.5万美金。合作研究者(Co-I)。


代表性论文:

1.Binbin Cheng, Wei-En Yuan, Jing Su, Yao Liu, Jianjun Chen*, Recent Advances in Small Molecule based Cancer Immunotherapy, Eur J Med Chem., 2018, 157: 582-598.

2.Xiaoxun Li, Peter D. Livant, Jianjun Chen*,An alkene-forming cascade reaction en route to 2,2'-bi(glycerol), SynLett, 2018; 29(13): 1769-1772.

3.Ling Li, Sibo Jiang, Xiaoxun Li, Yao Liu, Jing Su, Jianjun Chen*, Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site, Eur J Med Chem., 2018, 151, 482-494.

4.Xiaoshuang Guo; Yuan Cheng; Xiaotian Zhao; Yanli Luo; Jianjun Chen*;Wei-En Yuan*, Advances in redox-responsive drug delivery systems of tumor microenvironment, Journal of Nanobiotechnology, 2018, in press, DOI : 10.1186/s12951-018-0398-2.

5.Sibo Jiang, Yesenia L Franco, Yan Zhou, Jianjun Chen*, Nanotechnology in Retinal Drug Delivery, International Journal of Ophthalmology, 2018, 11(6), 1038-1044.

6.Zhongyao Cheng, Yumei Lian, Zul Kamal, Xin Ma, Jianjun Chen, Xinbo Zhou*, Jing Su*, Mingfeng Qiu*. Nanocrystals Technology for Pharmaceutical Science. Curr Pharm Des. 2018, in press, doi: 10.2174/1381612824666180518082420.

7.Xiaoming Li, Xiaoshuang Guo, Yuan Cheng, Xiaotian Zhao, Zhiwei Fang, Yanli Luo, Shujun Xia, Yun Feng, Jianjun Chen*, Wei-en Yuan*. pH-responsive cross-linked low molecular weight polyethylenimine as an efficient gene vector for delivery of plasmid DNA encoding anti-VEGF-shRNA for tumor treatment. Frontiers in Oncology, 2018, in press, doi: 10.3389/fonc.2018.00354.

8.Wang Bin, Yu Liu, Lianyan Huang, Jianjun Chen, Jing Jing Li, Ruishan Wang, Dehna M. Fong, Carles Justicia, Anna Planas, Deborah Young, Wei Li, Michael P. McDonald, Ruihong Chen & Francesca-Fang Liao, “A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in Alzheimer’s mice via HSF-1 mediated mechanism”, Molecular Psychiatry. 2017; 22(7): 990–1001.

9.Xuelan Tang, Ping Lu, Mingfeng Qiu, Jianjun Chen, Jing Sheng, Jing Su, “Screening PEGylated Polyethylenimine Derivatives for Safe and Efficient Delivery of Gene Materials”, Eur J Pharm Sci. 2017, 96:115-128.

10.Jianjun Chen*, Review of Design of Precursors for Sustainable Chemistry, Journal of Natural Products, 2017, 80 (5), 1701–1702.

11.Yanan Sun, Jing Su, Geyi Liu, Jianjun Chen, Xiumei Zhang, Ran Zhang, Minhan Jiang, Mingfeng Qiu, “Advances of blood cell-based drug delivery systems”, RSC Adv., 2016, 6, 106316–106326.

12.Chuan-Ling Si, Xiao-Feng Huang, Liang-Liang An, Cui-Yun Liu, Su Fan, Dan-Ni Xie, Yi-Mei Hong, Jianjun Chen*. “Extraction and Structural Characterization of Flavonoids from Twigs of Sophora japonica”. BioResources, 2015, 10 (4), 8397-8404.

13.Park Haeil, Chuan-Ling Si, Jianjun Chen*. “Total Synthesis of Amentoflavone”. Medicinal Chemistry, 2015, 5 (11), 467-469.

14.Elaine W. Tieu, Wei Li, Jianjun Chen, Tae-Kang Kim, Dejian Ma, Andrzej T. Slominski, and Robert C. Tuckey, “Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1”, Journal of Steroid Biochemistry and Molecular Biology, 2015, 149, 153–165.

15.Georgina N. Masoud, Jin Wang, Jianjun Chen, Duane Miller, Wei Li. “Design, Synthesis and Biological Evaluation of Novel HIF-1α Inhibitors”. Anticancer Research, 2015, 35 (7):3849-59.

16.Jianjun Chen, Jin Wang, Tae-Kang Kim, Elaine W Tieu, Edith Tang, Zongtao Lin, Dianne Kovacic, Duane D Miller, Arnold Postlethwaite, Robert Tuckey, Andrzej T Slominski, Wei Li, “Novel Vitamin D Analogs as Potential Therapeutics: Metabolism, Toxicity Profiling, and Antiproliferative Activity”, Anticancer Research, 2014, 34 (5), 2153-2163.

17.Jianjun Chen, Jin Wang, Luciana P.  Schwab, Kyung-Tae Park, Tiffany N Seagroves, Lisa K. Jennings, Duane D. Miller, Wei Li. “Benzimidazole analogs as potent hypoxia inducible factor inhibitors: synthesis, biological evaluation, and profiling drug-like properties”, Anticancer Research, 2014, 34 (8) 3891-3904.

18.Jin Wang, Jianjun Chen, Duane D. Miller and Wei Li, “Synergistic Combinations of Novel Tubulin Inhibitors and Vemurafenib Overcome Vemurafenib Acquired Resistance in BRAFV600E Melanoma”, Molecular Cancer Therapeutics, 2014, 13, 16-26.

19.Yan Lu, Jianjun Chen, Jin Wang,  Chien-Ming Li,  Sunjoo Ahn, Christina M. Barrett, James T. Dalton, Wei Li,  Duane D. Miller, “Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Colchicine Binding Site Tubulin Inhibitors as Potential Anticancer Agents”, Journal of Medicinal Chemistry, 2014, 57 (17), 7355–7366.

20.Robert C. Tuckey, Andrzej T. Slominski, Chloe Y. S. Cheng, Jianjun Chen, Tae-Kang Kim, Min Xiao and Wei Li. “Lumisterol is metabolized by CYP11A1: discovery of a new pathway”, The International Journal of Biochemistry & Cell Biology, 2014, 55, 24-34.

21.Jianjun Chen, Andrzej T. Slominski, Duane D. Miller, Wei Li. “Effects of sidechain length and composition on the kinetic conversion and product distribution of vitamin D3 analogs determined by real-time NMR”, Dermato-Endocrinology, 2013, 5, 142-149.

22.Andrzej T. Slominski, Tae-Kang Kim, Michal A.  Zmijewski, Zorica Janjetovic, Wei Li, Jianjun Chen, Ekaterina I. Kusniatsova, Igor Semak, Arnold Postlethwaite, Duane D. Miller, Jordan K. Zjawiony, Robert C. Tuckey. “Novel vitamin D photoproducts and their precursors in the skin”, Dermato-Endocrinology, 2013, 5, 8-19.

23.Edith K. Y. Tang, Jianjun Chen, Zorica Janjetovic, Elaine W. Tieu, Andrzej T. Slominski, Wei Li and Robert C. Tuckey. “Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1”, Drug Metabolism and Disposition, 2013, 41, 1112-1124.

24.Hovig Kouyoumdjian; David C. Zhu; Mohammad H. El-Dakdouki; Kelly Lorenz; Jianjun Chen; Wei Li; Xuefei Huang. “Glyconanoparticle Aided Detection of β-Amyloid by Magnetic Resonance Imaging and Attenuation of β-Amyloid Induced Cytotoxicity”, ACS Chemical Neuroscience, 2013, 4, 575-584.

25.Min Xiao, Sunjoo Ahn, Jin Wang, Jianjun Chen, Duane Miller, James Dalton, Wei Li. “Discovery of 4-Aryl-2-benzoyl-imidazoles As Tubulin Polymerization Inhibitor with Potent Antiproliferative Properties”, Journal of Medicinal Chemistry, 2013, 56, 3318–3329.

26.Jianjun Chen, Sunjoo Ahn, Jin Wang, Yan Lu, James T. Dalton, Duane D. Miller, Wei Li, “Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents”, Journal of Medicinal Chemistry, 2012, 55, 7285-7289.

27.Yan Lu, Jianjun Chen, Zorica Janjetovic, Phillip Michaels, Edith K Y Tang, Jin wang, Robert C. Tuckey, Andrzej T. Slominski, Wei Li, Duane D. Miller, "Design, Synthesis and Biological Behavior of the R-Epimer of 20-Hydroxyvitamin D3", Journal of Medicinal Chemistry, 2012, 55 (7), 3573–3577.

28.Zhao Wang, Jianjun Chen, Jin Wang, Sunjoo Ahn, Chien-Ming Li, Yan Lu, Vivian S. Loveless, James T. Dalton, Duane D. Miller, Wei Li, “Novel Tubulin Polymerization Inhibitors Overcome Multidrug Resistance and Reduce Melanoma Lung Metastasis”, Pharmaceutical Research, 2012, 29, 3040-3052.

29.Yan Lu, Jianjun Chen, Min Xiao, Wei Li, Duane D. Miller, “An Overview of Tubulin Inhibitors That Interact With the Colchicine Binding Site”, Pharmaceutical Research, 2012, 29, 2943-2971.

30.Elaine W. Tieu, Edith K. Y. Tang, Jianjun Chen, Wei Li, Minh N. Nguyen, Zorica Janjetovic, Andrzej Slominski and Robert C. Tuckey, “Rat CYP24A1 acts on 20-hydroxyvitamin D3 producing hydroxylated products with increased biological activity”, Biochemical Pharmacology, 2012, 84, 1696-1704.

31.Chien-Ming Li, Yan Lu, Jianjun Chen, Terrence A. Costello, Ramesh Narayanan, Mara N. Dalton, Linda M. Snyder, Sunjoo Ahn, Wei Li, Duane D. Miller, and James T. Dalton, “Orally Bioavailable Tubulin Antagonists for Paclitaxel-Refractory Cancer”, Pharmaceutical Research, 2012, 29, 3053-3063.

32.Andrzej T. Slominski, Tae-Kang Kim, Jianjun Chen, Minh N. Nguyen, Wei Li, Charles R. Yates, Trevor Sweatman, Robert C. Tuckey, "Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in the human placenta", The International Journal of Biochemistry & Cell Biology, 2012, 44, 2003-2018.

33.Robert C. Tuckey, Minh N. Nguyen, Jianjun Chen, Andrzej Slominski, Donna M. Baldisseri, Elaine W. Tieu, Jordan K. Zjawiony, and Wei Li, “Human cytochrome P450scc (CYP11A1) catalyses epoxide formation with ergosterol”, Drug Metabolism and Disposition, 2012, 40, 436-444.

34.Elaine W. Tieu, Wei Li, Jianjun Chen, Donna M. Baldisseri, Andrzej T. Slominski, and Robert C. Tuckey. “Metabolism of cholesterol, vitamin D3 and 20-hydroxyvitamin D3 incorporated into phospholipid vesicles by human CYP27A1”, Journal of Steroid Biochemistry and Molecular Biology, 2012, 129, 163-171.

35.Jin Wang, Andrzej Slominski, Robert Tuckey, Zorica Janjetovic, Anand Kulkarni, Jianjun Chen, Arnold E. Postlethwaite, Duane Miller, Wei Li, "20-Hydroxylvitamin D3 possesses high efficacy against proliferation of cancer cells while being non-toxic", Anticancer Research, 2012, 32, 739-746.

36.Mohammad H. El-Dakdouki; David C. Zhu; Kheireddine El-Boubbou; Medha Kamat; Jianjun Chen; Wei Li; Xuefei Huang. “Development of Multifunctional Hyaluronan Coated Nanoparticles for Imaging and Drug Delivery to Cancer Cells”. Biomacromolecules, 2012, 13 (4), 1144–1151.

37.Shivaputra A. Patila, Jin Wang, Xiaochen S. Li, Jianjun Chen,Terreia S. Jones, Amira Hosni- Ahmed, Renukadevi Patil, William L. Seibel, Wei Li, and Duane D. Millera, “New Substituted 4H-Chromenes as anti-cancer agents”. Bioorganic & Medicinal Chemistry Letters, 2012, 22, 4458-4461.

38.Tae-Kang Kim, Jin Wang, Zorica Janjetovic, Jianjun Chen, Robert C. Tuckey, Minh N. Nguyen, Edith K. Y. Tang, Duane Miller, Wei Li, and Andrzej T. Slominski, "Correlation between secosteroid induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength". Molecular and Cellular Endocrinology, 2012, 361, 143-152.

39.Andrzej T. Slominski1, Tae-Kang Kim, Haleem Z. Shehabi, Igor Semak, Edith K Y Tang, Minh N. Nguyen, Heather A. E. Benson, Elena Korik, Zorica Janjetovic, Jianjun Chen, Charles R. Yates, Arnold Postlethwaite, Wei Li, Robert C. Tuckey. “In vivo evidence for novel pathway of vitamin D3 metabolism initiated by P450scc”. FASEB J, 2012, 26, 7901-7915.

40.Jianjun Chen, Chien-Ming Li, Sunjoo Ahn, Jin Wang, Zhao Wang, Yan Lu, James Dalton, Duane. D. Miller, Wei Li, “Synthesis and antiproliferative activity of novel 2-aryl-4-benzoyl-imidazole derivatives targeting tubulin polymerization”. Bioorganic & Medicinal Chemistry, 2011, 19, 4782–4795.

41.Chien-Ming Li, Jianjun Chen, Yan Lu, Ramesh Narayanan, Deanna N. Parke, Wei Li, Duane D. Miller, and James T. Dalton, “Pharmacokinetic Optimization of 4-Substituted Methoxybenzoyl-Aryl-Thiazole (SMART) and 2-Aryl-4-Benzoyl-Imidazole (ABI) for Improving Oral Bioavailability”, Drug Metabolism and Disposition, 2011, 39:1833-1839.

42.Michal A. Zmijewski, Wei Li, Jianjun Chen, Tae-Kang Kim, Jordan K. Zjawiony, , Trevor W. Sweatman, Duane D. Miller and Andrzej T. Slominski, “Synthesis and photochemical transformation of  3β, 21-dihydroxypregna-5,7-dien-20-one to biologically active products”, Steroids, 2011, 76, 193-203.

43.Yan Lu, Chien-Ming Li, Zhao Wang, Jianjun Chen, Michael Mohler, Wei Li, James Dalton, Miller, Duane, “Design, Synthesis, and SAR Studies of 4-Substituted Methoxylbenzoyl-aryl-thiazoles Analogues as Potent and Orally Bioavailable Anticancer Agents", Journal of Medicinal Chemistry, 2011, 54(13), 4678–4693.

44.Robert C. Tuckey, Wei Li, Haleem Z. Shehabi, Zorica Janjetovic, Minh N. Nguyen, Tae-Kang Kim, Jianjun Chen, Danielle E. Howell, Heather A. E. Benson, Trevor Sweatman, Donna M. Baldisseri, and Andrzej Slominski. Production of 22-hydroxy-metabolites of vitamin D3 by cytochrome P450scc (CYP11A1) and analysis of their biological activities on skin cells. Drug Metabolism and Disposition, 2011, 39,1577-1588.

45.Andrzej Slominski, Wei Li, Syamal K. Bhattacharya, Richard A. Smith, Patricia Johnson, Jianjun Chen, Kathleen Nelson, Robert C Tuckey, Duane Miller, Arnold E. Postlethwaite, “Novel Vitamin D Analogues 17,20S(OH)2pD and 17,20R(OH)2pD are Noncalcemic and Show Antifibrotic Activity”, The Journal of Investigative Dermatology, 2011, 131, 1167–1169.

46.Andrzej T. Slominski, Tae-Kang Kim, Zorica Janjetovic, Robert C. Tuckey, Radoslaw Bieniek, Junming Yue, Wei Li, Jianjun Chen, Minh N. Nguyen, Duane Miller, Tai C. Chen, Michael Holick, “20-hydroxyvitamin D2 is a non-calcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells”, American Journal of Physiology Cell Physiology, 2011, 300, C526-C541.

47.Jianjun Chen, Zhao Wang, Chien-Ming Li, Yan Lu, Pavan K. Vaddady, Bernd Meibohm, James Dalton, Duane. D. Miller, Wei Li, “Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents”, Journal of Medicinal Chemistry, 2010, 53, 7414–7427.

48.Wei Li, Jianjun Chen, Zorica Janjetovic, Tae-Kang Kim, Trevor Sweatsman, Jordan Zjawiony, Robert C Tuckey, Duane Miller, Andrzej Slominski, “Chemical Synthesis of 20S-hydroxyvitamin D3, which shows anti-proliferative activity”, Steroids, 2010, 75, 926-935.

49.Tae-Kang Kim, Jianjun Chen*(equal contribution), Wei Li, Jordan Zjawiony, Duane Miller, Zorica Janjetovic, Andrzej Slominski, “A New Steroidal 5,7-Diene Derivative, 3β-Hydroxyandrosta-5, 7-Diene-17β-Carboxylic Acid, Shows Potent Anti-proliferative Activity”, Steroids, 75(3), 230-239, (2010). Corrigendum in Steroids, 2010, 75(13-14), 1164.

50.Yan Lu, Zhao Wang, Chien-Ming Li, Jianjun Chen, James T. Dalton, Wei Li, and Duane D. Miller, “Synthesis, In Vitro Structure-Activity Relationship, and In Vivo Studies of 2-Arylthiazolidine-4-Carboxylic Acid Amides as Anticancer Agents”, Bioorganic & Medicinal Chemistry, 2010, 18(2), 477-495.

51.Jianjun Chen, Jiang-Wei Zhang, Ling Yang and Wei Li, “Structure elucidation of major metabolites from medroxyprogesterone acetate by P450”, Chemical & Pharmaceutical Bulletin, 2009, 57(8) 835-839.

52.Yan Lu, Zhao Wang, Chien-Ming Li, Jianjun Chen, James Dalton, Wei Li, Duane D. Miller, “Synthesis and SAR study of 2-aryl-thiazolidine-4-carboxamide analogues for melanoma and prostate cancer”, Journal of Medicinal Chemistry, 2009, 52, 1701-1711.

53.Michal A. Zmijewski, Wei Li, Jordan K. Zjawiony, Trevor W. Sweatman, Jianjun Chen, Duane D. Miller and Andrzej T. Slominski, “Photo-conversion of two epimers (20R and 20S) of pregna-5, 7-diene-3β, 17α, 20-triol and their bioactivity in melanoma cells”, Steroids, 2008, 74(2), 218-228.

54.Jianjun Chen, Zhao Wang, Yan Lu, Duane D. Miller, Wei Li, “Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma”, Bioorganic & Medicinal Chemistry Letters, 2008, 18, 3183–3187.

55.Michal A. Zmijewski, Wei Li, Jordan K. Zjawiony, Trevor W. Sweatman, Jianjun Chen, Duane D. Miller and Andrzej T. Slominski, “Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives”, Photochemical & Photobiological Sciences, 2008, 7, 1570-1576.

56.Jianjun Chen, Hyeun Wook Chang, Hyun Pyo Kim and Haeil Park, “Synthesis of Phospholipase A2 Inhibitory Biflavonoids”, Bioorganic & Medicinal Chemistry Letters, 2006, 16, 2373-2375.

 

代表性专利:

1.Compounds for treatment of cancer. JP 2016510748; US 20160015688; US 10022356; MX 2015011713; IN 2015DN08964. Wang, Jin; Chen, Jianjun; Miller, Duane D.; Li, Wei.

2.Preparation of imidazole-containing compounds and analogs useful in the treatment of cancer. KR 2016-7017425 A3; KR 2017-7006276; AU 2015202828;. Miller, Duane D.; Wei, Li; Chen, Jianjun; Dalton, James T.; Li, Chien-Ming; Ahn, Sunjoo.

3.Preparation of aryl- and heterocyclic compounds for treatment of cancer and drug-resistant tumors. IN 201718037031. Lu, Yan; Li, Chien-Ming; Wang, Zhao; Chen, Jianjun; Li, Wei; Dalton, James T.; Miller, Duane D.; Duke, Charles; Ahn, Sunjoo.

4.Aroylazole compounds as anticancer agents and their preparation and use for treatment of cancers and drug resistant cancers. US 20180093971. Lu, Yan; Li, Chien-Ming; Wang, Zhao; Chen, Jianjun; Li, Wei; Dalton, James T.; Miller, Duane D.; Duke, Charles; Ahn, Sunjoo.  

5.Preparation of aryl- and heterocyclic compounds for treatment of cancer and drug-resistant tumors. JP 2017008091.  Dalton, James T.; Miller, Duane D.; Ahn, Sunjoo; Chen, Jianjun; Duke, Charles; Li, Chien-Ming; Li, Wei; Lu, Yan; Wang, Zhao.

6.Enzymatic production or chemical synthesis and uses for androsta-5,7-dienes or pregna-5,7-dienes and UVB conversion products thereof. US 20140200201. Zjawiony, Jordan K.; Li, Wei; Zbytek, Blazej; Tuckey, Robert C.; Zjawiony Jordan, K.; Nguyen, Minh Ngoc; Zmijewski, Michal A.; Janjetovic, Zorica; Sweatman, Trevor W.; Miller, Duane D.; Chen, Jianjun.

7.Preparation of azole compounds for treatment of cancer. IN 201718037031. Miller, Duane D.; Li, Wei; Wang, Zhao; Lu, Yan; Chen, Jianjun; Dalton, James T.; Li, Chien-Ming.

8.Azoles and related compounds for treatment of cancer and their preparation. US 20170226086; Li, Wei; Xiao, Mi; Dalton, James; Ahn, Sunjoo; Miller, Duane D.; Chen, Jianjun; Wang, Jin.

9.Compounds for treatment of cancer. WO 2014138279; AU 2014225761; KR 2015123328. By Wang, Jin; Chen, Jianjun; Miller, Duane D.; Li, Wei.

10.Preparation of azole compounds for treatment of cancer. US 12/485,881. Miller, Duane D.; Li, Wei; Wang, Zhao; Lu, Yan; Chen, Jianjun; Dalton, James T.; Li, Chien-Ming.  

11.Enzymatic production or chemical synthesis and uses for androsta-5,7-dienes or pregna-5,7-dienes and UVB conversion products thereof. US 12/807,178. Andrzej T. Slominski.; Li, Wei; Zbytek, Blazej; Tuckey, Robert C.; Zjawiony Jordan, K.; Nguyen, Minh Ngoc; Zmijewskl Michal, A.; Janjetovic, Zorica; Sweatman Trevor, W.; Miller, Duane D.; Chen, Jianjun, Postlethwaite, Arnold E.

12.Design, synthesis and biological studies of a new class of cytotoxic agents, 2-arylthiazolidine-4-carboxylic acid amides for prostate cancer, 2014.US 7,307,093; US 7,662,842; US 8,592,465; Mexico 262836; Japan 5507552; Russian Federation 2514427. Jianjun Chen, James Dalton, Duke Charles, Dongjin Hwang, Wei Li, Chien-Ming Li, Yan Lu, Duane Miller, Zhao Wang.

 

上一条:Kutty Selva Nandakumar
下一条:喻志强