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周春

 

 

姓名:周春
职称:副教授
联系邮箱:zhouch27@mail2.sysu.edu.cn
联系电话:61648813

学习经历:
2006.9-2010.7 中国药科大学,生物技术,学士
2010.9-2015.7 中山大学,药理学,硕博连读
2015.8-2015.10 弗吉尼亚联邦大学,博士后

研究方向:
破骨细胞分化及骨吸收机制
类风湿关节炎发病机制及治疗药物筛选
细胞信号转导机制

代表性论文:
1. Zhou C, You Y, Shen W, Zhu YZ, Peng J, et al. (2015) Deficiency of sorting nexin 10 prevents bone erosion in collagen-induced mouse arthritis through promoting NFATc1 degradation. Ann Rheum Dis. (Epub ahead of print)
2. Zhou C, Li C, Li D, Wang Y, Shao W, et al. (2013) BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein regulates neurite development via PI3K-AKT and ERK signaling pathways. Neuroscience 254: 361-368.

3. Zhang XW, Zhou C, Zhu HD, Shao W, You Y, et al. (2014) Inhibition of osteoclastogenesis by 6-[10'(Z)-heptadecenyl] salicylic acid from Syzygium tetragonum Wall via preventing nuclear translocation of NFATc1. Phytomedicine 21: 960-965. co-author 4. You, Y., Zhou, C., Li, D., Cao, Z.L., Shen, W., Li, W.Z., Zhang, S., Hu, B. & Shen, X. (2016) Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis. Sci Rep, 6, 20630. doi: 10.1038/srep20630.
5. Lin S, Zhou C, Neufeld E, Wang YH, Xu SW, et al. (2013) BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein modulates ATP-binding cassette transporter A-1 trafficking and function. Arterioscler Thromb Vasc Biol 33: e31-38.
6. Li C, Zhou C, Wang S, Feng Y, Lin W, et al. (2011) Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3beta/beta-catenin signaling pathway. PLoS One 6: e27053.
7. Li C, Chen S, Yu Y, Zhou C, Wang Y, et al. (2013) BIG1, a Brefeldin A-Inhibited Guanine Nucleotide-Exchange Factor, Is Required for GABA-Gated Cl Influx Through Regulation of GABA Receptor Trafficking. Mol Neurobiol.
8. Shao W, Li D, Peng J, Chen S, Zhou C, et al. (2014) Inhibitory effect of ethyl acetate extract of Aristolochia yunnanensis on cardiac fibrosis through extracellular signal-regulated kinases 1/2 and transforming growth factor beta/small mother against decapentaplegic signaling pathways. Transl Res 163: 160-170.
9. Li Y, Wang S, Wang Y, Zhou C, Chen G, et al. (2013) Inhibitory effect of the antimalarial agent artesunate on collagen-induced arthritis in rats through nuclear factor kappa B and mitogen-activated protein kinase signaling pathway. Transl Res 161: 89-98.
10. Wang Y, Wang S, Li Y, Jiang J, Zhou C, et al. (2015) Therapeutic effect of Cryptotanshinone on collagen-induced arthritis in rats via inhibiting nuclear factor kappa B signaling pathway. Transl Res 165(6): 704-16.

11. Lu L, Li C, Li D, Wang Y, Zhou C, et al. (2013) Cryptotanshinone inhibits human glioma cell proliferation by suppressing STAT3 signaling. Mol Cell Biochem 381: 273-282.
12. Lin W, Wang Y, Lin S, Li C, Zhou C, et al. (2012) Induction of cell cycle arrest by the carbazole alkaloid Clauszoline-I from Clausena vestita D. D. Tao via inhibition of the PKCdelta phosphorylation. Eur J Med Chem 47: 214-220.

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