中国南方医科大学与瑞典卡罗林斯卡医学院联合招聘博士后公告

1) Postdoc in experimental immunology (MIR-1601)
A postdoc position in a project to investigate basic mechanisms and development of a vaccine for rheumatoid arthritis is now open. The employment will be placed at Southern Medical University, but the location will initially be mainly at Karolinska Institute, Sweden and later at Southern Medical University, China.
Form of employment:
Full-time, 3 years (with a trial period financed by stipend for 6 months), with a possibility for prolongation.
Start: as soon as possible.
Apply before: March 25, 2016.
Description:
Applications are invited for a position as a postdoc in a project led by Prof. Rikard Holmdahl. The task is to develop a vaccine for rheumatoid arthritis.
Project:
The project aims to analyse the immune mechanism for vaccination against arthritis, mainly using experimental animal models. The vaccine is based on unique antigenic epitopes derived from specific joint proteins. The project is designed to investigate the basic mechanism of B and T cell tolerance of importance for the vaccination effect. This work is done primarily in mouse models in which epitopes and interacting molecules have been genetically modified. As the epitopes in the vaccine it is shared between mice and humans, and we will have unique mouse strains with humanized immune receptors. The main work will be done with experimental animals and an excellent platform for the work will be available. The overall goal is to contribute in the development of vaccine against rheumatoid arthritis and to publish the results findings related to basic mechanisms in autoimmunity and vaccination results in leading international journals.
Qualifications:
To qualify, the applicant must hold a PhD in medicine or biological science. Fluent English is an absolute requirement as the lab working language is English. Training and excellence in experimental immunology and with experimental mouse systems is a requirement. Computer skills, bioinformatics and statistical knowledge are needed.
Contact and Application:
Apply directly to Angel Yao Mattisson (Angel.Yao-Mattisson@ki.se). Please mention the job number (MIR-1601) in your application.

2) Postdoc in experimental immunology (MIR-1602)
A postdoc position in a project to investigate the role of antibodies to regulate and mediate arthritis. The employment will be placed at Southern Medical University, but the location will initially be mainly at Karolinska Institute, Sweden and later at Southern Medical University, China.
Form of employment:
Full-time, 3 years (with a trial period financed by stipend for 6 months), with a possibility for prolongation.
Start: as soon as possible.
Apply before: March 25, 2016.
Description:
Applications are invited for a position as a postdoc in a project led by Prof. Rikard Holmdahl. The task is to develop multiplex assays for detection of antibodies to defined protein epitopes and to analyze both experimental animal models and human samples.
Project:
The project aims to develop a diagnostic test against rheumatoid arthritis and other inflammatory joint diseases. The test is based on unique antigenic epitopes derived from specific joint proteins. The project is designed to investigate the basic mechanisms whereby antibodies cause and regulate arthritis. This work is done primarily in mouse models in which epitopes and interacting molecules have been genetically modified. As the target structures are shared between mice and humans there are possibilities to make in depth functional analysis also with human samples. The main work will be done with experimental animals and an excellent platform for the work will be available. The goal is to contribute in the development of a diagnostic test for rheumatoid arthritis and to publish the results findings related to basic mechanisms in autoimmunity in leading international journals.
Qualifications:
To qualify, the applicant must hold a PhD in medicine or biological science. Fluent English is an absolute requirement as the lab working language is English. Training and excellence in experimental immunology and with experimental mouse systems is a requirement. Computer skills, bioinformatics and statistical knowledge are needed.
Contact and Application:
Apply directly to Angel Yao Mattisson (Angel.Yao-Mattisson@ki.se). Please mention the job number (MIR-1602) in your application.

3) Postdoc in applied bioinformatics (MIR-1603)
A postdoc position in a project to develop a diagnostic biomarker assay for rheumatoid arthritis is now open. The employment will be placed at Southern Medical University, but the location will initially be mainly at Karolinska Institute, Sweden and later at Southern Medical University, China.
Form of employment:
Full-time, 3 years (with a trial employment for 6 months) and with a possibility of prolongation.
Start: as soon as possible.
Apply before: March 25, 2015.
Description:
Applications are invited for a position as a postdoc in a project led by Prof. Rikard Holmdahl. The task is to develop multiplex assays for detection of antibodies to defined protein epitopes and to analyze both experimental animal models and human samples.
Project:
The project aims to develop a diagnostic test for rheumatoid arthritis. The test is based on unique antigenic epitopes derived from various joint proteins. The epitopes has been formulate as conformational peptides but needs to be further improved regarding their functional and diagnostic role. As these peptides and epitopes are shared between mice and humans that are possibilities to make in depth functional analysis in the mouse as well as testing of human sera for assay development. The assay development will be developed using a multiplex platform, and also analyzed in detail regarding their physical properties. The project involve both in depth analyses and the coordination of large cohorts. This includes analyses with quantitative statistics to associate laboratory dats with clinical traits. It will also involve pathway analysis of the relevant immune cells based on expression and proteomic data. Besides the laboratory work the position will also involve coordination of the project with participating clinicians in both China and Europe. The goal is to develop a suitable diagnostic test and to publish the results in leading international journals.
Qualifications:
To qualify, the applicant must hold a PhD in medicine or biological science. Fluent English is an absolute requirement as the lab working language is English. Easiness with social communication are requirements. Computer skills, bioinformatics knowledge and statistical analysis are needed. Laboratory experience and excellence is a requirement.
Contact and Application:
Apply directly to Angel Yao Mattisson (Angel.Yao-Mattisson@ki.se). Please mention the job number (MIR-1603) in your application.