Tianming Gao, Ph.D.

Date: 2021-01-26 Views:

Tianming Gao, Ph.D.

Director of Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence

Academician of the chinese academy of engineering / Chair Professor of Cheung Kong Scholars Programme, China / the National Science Fund for Distinguished Young Scholars

Research Interest:New targets and new methods for antidepression and antianxiety

E-mail: tgao@smu.edu.cn

Selected publications

1. Cao X, Li LP, Wang Q, Wu Q,Hu HH, Zhang M, Fang YY, Zhang J, Li SJ, Xiong WC, Yan HC, Gao YB, Liu JH, Li XW, Sun LR, Zeng YN, Zhu XH#Gao TM#. Astrocyte-derived ATP modulates depressive-like behaviors. Nat Med 2013 Jun;19(6):773-7.

2. Li BX, Jie W, Huang LY, Wei P, Li SJ, Luo ZY, Friedman AK, Meredith AL, Han MH, Zhu XH, Gao TM#. Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling. Nat Neurosci. 2014 Aug;17(8):1055-63.

3. Lu YS, Sun XD, Hou FQ,Bi LL,Yin DM,Liu F,Chen YJ, Bean JC, Jiao HF, Liu XH, Li BM, Xiong WC,Gao TM#, Mei L#. Maintenance of GABAergic Activity by Neuregulin 1-ErbB4 in Amygdala for Fear Memory. Neuron 2014 Nov;84(4):835-46.

4. Woo RS, Li XM, Tao Y, Carpenter-Hyland E, Huang YZ, Weber J, Neiswender H, Dong XP, Wu J, Gassmann M, Lai C, Xiong WC, Gao TM#, Mei L#. Neuregulin-1 Enhances Depolarization-induced GABA Release. Neuron 2007 May;54(4):599-610.

5. Chen YH, Wu JL, Hu NY, Zhuang JP, Li WP, Zhang SR, Li XW, Yang JM, Gao TM#. Distinct projections from the infralimbic cortex exert opposing effects in modulating anxiety and fear. J Clin Invest. 2021 Jul 15;131(14):e145692.

6. Zou WJ, Song YL, Wu MY, Chen XT, You QL, Yang Q, Luo ZY, Huang L, Kong Y, Feng J, Fang DX, Li XW, Yang JM, Mei L, Gao TM#. A discrete serotonergic circuit regulates vulnerability to social stress. Nat Commun 2020 Aug 24;11:4218.

7. Liu JH, Wang Q, You QL, Li ZL, Hu NY, Wang Y, Jin ZL, Li SJ, Li XW, Yang JM, Zhu XH, Dai YF, Xu JP, Bai XC, Gao TM#. Acute EPA-induced learning and memory impairment in mice is prevented by DHA. Nat Commun. 2020 Oct 29;11(1):5465.

8. Chen YH, Hu NY, Wu DY, Bi LL, Luo ZY, Huang L, Wu JL, Wang ML, Li JT, Song YL, Zhang SR, Jie W, Li XW, Zhang SZ, Yang JM, Gao TM#. PV network plasticity mediated by neuregulin1-ErbB4 signalling controls fear extinction. Mol Psychiatry. 2022 Feb;27(2):896-906.

9. Luo ZY, Huang L, Lin S, Yin YN, Jie W, Hu NY, Hu YY, Guan YF, Liu JH, You QL, Chen YH, Luo ZC, Zhang SR, Li XW, Yang JM, Tao YM, Mei L#, Gao TM#. Erbin in amygdala parvalbumin-positive neurons modulates anxiety-like behaviors. Biol Psychiatry. 2020 May; 87(10):926-936.

10. Chen YJ, Zhang M, Yin DM, Wen L, Ting A, Wang P, Lu YS, Zhu XH, Li SJ, Wu CY, Wang XM, Lai C, Xiong WC, Mei L#, Gao TM#. ErbB4 in parvalbumin-positive interneurons is critical for neuregulin 1 regulation of long-term potentiation. Proc Natl Acad Sci USA. 2010 Dec;107(50):21818-23.




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