Tianming Gao, Ph.D.
| Tianming Gao, Ph.D. Director of Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence Academician of the chinese academy of engineering / Chair Professor of Cheung Kong Scholars Programme, China / the National Science Fund for Distinguished Young Scholars Research Interest：New targets and new methods for antidepression and antianxiety E-mail: tgao@smu.edu.cn |
Selected publications
1. Cao X, Li LP, Wang Q, Wu Q,Hu HH, Zhang M, Fang YY, Zhang J, Li SJ, Xiong WC, Yan HC, Gao YB, Liu JH, Li XW, Sun LR, Zeng YN, Zhu XH#，Gao TM#. Astrocyte-derived ATP modulates depressive-like behaviors. Nat Med 2013 Jun;19(6):773-7.
2. Li BX, Jie W, Huang LY, Wei P, Li SJ, Luo ZY, Friedman AK, Meredith AL, Han MH, Zhu XH, Gao TM#. Nuclear BK channels regulate gene expression via the control of nuclear calcium signaling. Nat Neurosci. 2014 Aug;17(8):1055-63.
3. Lu YS, Sun XD, Hou FQ，Bi LL，Yin DM，Liu F，Chen YJ, Bean JC, Jiao HF, Liu XH, Li BM, Xiong WC，Gao TM#, Mei L#. Maintenance of GABAergic Activity by Neuregulin 1-ErbB4 in Amygdala for Fear Memory. Neuron 2014 Nov;84(4):835-46.
4. Chen YH, Wu JL, Hu NY, Zhuang JP, Li WP, Zhang SR, Li XW, Yang JM, Gao TM#. Distinct projections from the infralimbic cortex exert opposing effects in modulating anxiety and fear. J Clin Invest. 2021 Jul 15;131(14):e145692.
5. Zou WJ, Song YL, Wu MY, Chen XT, You QL, Yang Q, Luo ZY, Huang L, Kong Y, Feng J, Fang DX, Li XW, Yang JM, Mei L, Gao TM#. A discrete serotonergic circuit regulates vulnerability to social stress. Nat Commun 2020 Aug 24;11(1):4218.
6. Wang Q, Kong Y, Wu DY, Liu JH, Jie W, You QL, Huang L, Hu J, Chu HD, Gao F, Hu NY, Luo ZC, Li XW, Li SJ, Wu ZF, Li YL, Yang JM#, Gao TM#. Impaired calcium signaling in astrocytes modulates autism spectrum disorder-like behaviors in mice. Nat Commun. 2021 May 31;12(1):3321.
7. Wu JL, Li ZM, Chen H, Chen WJ, Hu NY, Jin SY, Li XW, Chen YH, Yang JM, Gao TM#. Distinct septo-hippocampal cholinergic projections separately mediate stress-induced emotional and cognitive deficits. Sci Adv. 2024 Nov 8;10(45):eado1508.
8. Liu JH, Zhang M, Wang Q, Wu DY, Jie W, Hu NY, Lan JZ, Zeng K, Li SJ, Li XW, Yang JM, Gao TM#. Distinct roles of astroglia and neurons in synaptic plasticity and memory. Mol Psychiatry. 2022 Feb;27(2):873-885.
9. Lin S, Huang L, Luo ZC, Li X, Jin SY, Du ZJ, Wu DY, Xiong WC, Huang L, Luo ZY, Song YL, Wang Q, Liu XW, Ma RJ, Wang ML, Ren CR, Yang JM, Gao TM#. The ATP Level in the Medial Prefrontal Cortex Regulates Depressive-like Behavior via the Medial Prefrontal Cortex-Lateral Habenula Pathway. Biol Psychiatry. 2022 Aug 1;92(3):179-192.
10. Chen YJ, Zhang M, Yin DM, Wen L, Ting A, Wang P, Lu YS, Zhu XH, Li SJ, Wu CY, Wang XM, Lai C, Xiong WC, Mei L#, Gao TM#. ErbB4 in parvalbumin-positive interneurons is critical for neuregulin 1 regulation of long-term potentiation. Proc Natl Acad Sci USA. 2010 Dec;107(50):21818-23.
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