Xin Luo, Ph.D.

Date: 2023-10-07 Views:


Xin Luo, Ph.D.

Professor / Principal Investigator

Research Interest: 

Neuroimmune regulation of chronic pain; 

Neuroimmune regulation of tissue wounding and repairing; 

Neural mechanisms underlying the effects of anesthetic agents

E-mail: xin.luo21@hotmail.com


Publications

1. Xin Luo*, Jasmine Ji, Ru-Rong Ji (2023). Sex Differences in Pain with Emphasis on Neuroimmune Interactions. In: Ji, RR., Cheng, J., Ji, J. (eds) Neuroimmune Interactions in Pain . Springer Nature. (*correspondent authors)

2. Xin Luo*, Ouyang Chen, Zilong Wang, Sangsu Bang, Jasmine Ji, Sang Hoon Lee, Yul Huh, Kenta Furutani, Qianru He, Xueshu Tao, Mei-Chuan Ko, Andrey Bortsov, Christopher R Donnelly, Yong Chen, Andrea Nackley, Temugin Berta, and Ru-Rong Ji*. IL-23/IL-17A/TRPV1 Axis Produces Mechanical Pain via Macrophage-Sensory Neuron Crosstalk in Female Mice (2021) Neuron 109: 2691-2706. (*co-correspondent authors) (IF=18.688)

Featured in Neuron by Dawes and Bennett (2021)

Featured in Neuroscience Bulletin by Tan et al. (2021)

Highlighted in the IASP Pain Research Forum (https://www.painresearchforum.org/news/183436-sex-specific-differences-pain-mechanism)

3. Sangsu Bang#, Christopher R Donnelly#, Xin Luo#, Maria Toro Moreno#, Xueshu Tao, Zilong Wang, Sharat Chandra, Andrey V Bortsov, Emily R. Derbyshire, and Ru-Rong Ji. Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice. (2021) Nature Communications 12: 1704. (#co-first authors) (IF=17.694)

4 Jasmine Ji#, Qianru He#, Xin Luo#, Sangsu Bang, Aidan Mcginnis, Andrea G Nackley, and Ru-Rong Ji. Innate-Immune Sensing by Nociceptors IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice (2021) Frontiers in Immunology 12: 5009. (#co-first authors) (IF=8.786)

5. Christopher R Donnelly, Changyu Jiang, Amanda S Andriessen, Kaiyuan Wang, Zilong Wang, Huiping Ding, Junli Zhao, Xin Luo, Michael S Lee, Yu L Lei, William Maixner, Mei-Chuan Ko, Ru- Rong Ji. (2021) STING controls nociception via type I interferon signaling in sensory neurons. (2021) Nature 591(7849): 275-280. (IF=69.504)

6. Xin Luo*, Yul Hul, Sangsu Bang, Qianru He, Linlin Zhang, Megumi Matsuda, and Ru-Rong Ji*. Macrophage TLR9 Contributes to Chemotherapy-induced Neuropathic Pain in Male Mice. (2019) Journal of Neuroscience 39(35): 6848-6864. (*co-correspondent authors) (IF=6.709)

7. Xin Luo, Yun Gu, Xueshu Tao, Charles N Serhan, Ru-Rong Ji. Resolvin D5 inhibits neuropathic pain and inflammatory pain in male but not female mice: Distinct sex-dependence of D-series resolvins in pain regulation (2019) Frontiers in Pharmacology 10: 745. (IF=5.988)

8. Xin Luo*, Bethany Fitzsimmons, Apoorva Mohan, Linlin Zhang, Niccolo Terrando, Holly Kordasiewicz, Ru-Rong Ji*. Intrathecal administration of antisense oligonucleotide against p38α but not p38β MAP kinase isoform reduces neuropathic and postoperative pain and TLR4-induced pain in male mice. (2018) Brain, Behavior, and Immunity 72: 34-44 (*co-correspondent authors). (IF=19.277)





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