一、教学
讲授《法医学概论》《法医学》《法医病理学》《法医毒理学》《法医现场学》《医疗纠纷鉴定与防范》《高级法医学》等课程。
二、研究领域
法医病理学与法医毒理学 (1)甲基苯丙胺(METH)的中枢神经系统损伤研究;(2)糖尿病心肌病(DbCM)心衰机制及相关死亡原因研究。
三、学术兼职
教育部科技管理专家库成员,教育部学位论文评审专家库成员,中国法医学会法医病理学分会委员,中国毒理学会药物依赖性分委会委员,广东省高层次人才评审专家,广东省司法鉴定协会理事、法医病理分委会副主任委员,广州市司法鉴定协会副会长等。
四、个人成果
1. 学术论文
黄阅兵,邱海,陈雯,孟子邻,蔡雨,岳霞*,乔东访*. 致死性心律失常大鼠的蛋白质组学研究. 中国法医学杂志, 2025, 40(4): 444-449.(Chin J Forensic Med, 2025, Vol.40, No.4) doi:10.13618/j.issn.1001-5728.2025.04.011 (中文核心期刊,ISSN 1001-5728,2025年8月发表)
H Qiu, X Yue, YB Huang, ZL Meng, JH Wang* and DF Qiao*. Hippocampal single-cell RNA Atlas of chronic methamphetamine abuse-induced cognitive decline in mice. eLife, posted May 8, 2025. doi: https://doi.org/10.1101/2025.05.02.651823
Yuebing Huang , Hai Qiu , Wen Chen , Zilin Meng , Yu Cai , Dongfang Qiao *, Xia Yue *. Identification of TRAF2, CAMK2G, and TIMM17A as biomarkers distinguishing mechanical asphyxia from sudden cardiac death base on 4D-DIA Proteomics: A pilot study. Journal of Pharmaceutical and Biomedical Analysis, 258 (2025) 116730. doi:10.1016/j.jpba.2025.116730 (SCIE,小类2区,3.1,Received 3 November 2024; Received in revised form 10 January 2025; Accepted 2 February 2025)
Yuebing Huang, Hai Qiu, Qianling Chen, Zilin Meng, Dongfang Qiao*, Xia Yue*. Exploring Potential Diagnostic Biomarkers for MechanicalAsphyxia in the Heart Based on Proteomics Technology. International Journal of Molecular Sciences. 2024, 25, 12710. https://doi.org/10.3390/ijms252312710 (SCIE , 小类2区, Impact Factor: 5.7, Published: 26 November 2024 )
Lingyue Li, Zilin Meng ,Yuebing Huang ,Luyao Xu, Qianling Chen, Dongfang Qiao*, Xia Yue*. Chronic Sleep Deprivation Causes Anxiety, Depression and Impaired Gut Barrier in Female Mice-Correlation Analysis from Fecal Microbiome and Metabolome. Biomedicines, 2024, 12,2654. https://doi.org/10.3390/biomedicines12122654 (SCIE, 小类2区, Impact Factor: 4.2. Published: 21 November 2024)
景嘉钰#,徐璐瑶,杜思昊,岳霞,乔东访*. 宏基因组测序辅助鉴定输液致血流感染死亡 1 例[J]. 法医学杂志, 2024, 40(2): 211-216. Doi:10.12116/j.issn.1004-5619.2023.430407 ( JING JY,XU LY,DU SH,et al. Metagenomic sequencing assisted in the identification of death due to infusion-induced bloodstream infection: A case report[J]. Fa yi xue Za zhi, 40(2): 211-216.)
Jiayu Jing#, Cui Zhang#, Sihao Du, Xiaohui Tan, Xia Yue, Dongfang Qiao*. Sudden death with cardiac involvement in a neonate with carnitine-acylcarnitine translocase deficiency. Cardiovascular Pathology. 70(2024)107630. https://doi.org/10.1016/j.carpath.2024.107630 (SCIE, 小类3区, 3.7, Received 17 January 2024, Revised 22 February 2024, Accepted 5 March 2024)
Qianling Chen, Lingyue Li, Luyao Xu, Bin Yang, Yuebing Huang, Dongfang Qiao*, Xia Yue*. Proteomic analysis discovers potential biomarkers of early traumatic axonal injury in the brainstem. Int J Legal Med. (2024) 138:207–227 https://doi.org/10.1007/s00414-023-03039-5 (SCIE, 小类1区, 2.791, Received: 14 December 2022 / Accepted: 1 June 2023 / Published: 20 June 2023)
Xuebing Chen, Luyao Xu, Qianling Chen, Shuying Su, Jingshen Zhuang *, Dongfang Qiao*. Polystyrene micro- and nanoparticles exposure induced anxiety-like behaviors, gut microbiota dysbiosis and metabolism disorder in adult mice. Ecotoxicology and Environmental Safety. 259 (2023) 115000. https://doi.org/10.1016/j.ecoenv.2023.115000 (SCIE, 小类1区, 7.129, Accepted 8 May 2023, Online 19 May 2023)
Luyao Xu, Xiaohui Tan, Xuebing Chen, Sihao Du, Xia Yue, Dongfang Qiao*. Rare, fatal pulmonary fat embolism after acupuncture therapy: A case report and literature review. Forensic Science International. 345(2023)111619. https://doi.org/10.1016/j.forsciint.2023.111619 (SCIE, 小类3区, 2.676, Accepted 25 February 2023, Available online 27 February 2023)
Luyao Xu, Lingyue Li, Qianling Chen, Yuebing Huang, Xuebing Chen*, Dongfang Qiao*. The Role of Non‑coding RNAs in Methamphetamine‑Induced Neurotoxicity. Cellular and Molecular Neurobiology. (2023) 43:2415–2436. https://doi.org/10.1007/s10571-023-01323-x (SCIE,小类3区,4.231, Accepted: 20 January 2023.)
Qianling Chen, Xuebing Chen, Luyao Xu, Rui Zhang, Zhigang Li*, Xia Yue*, Dongfang Qiao*. Traumatic axonal injury: neuropathological features, postmortem diagnostic methods, and strategies. Forensic Science, Medicine and Pathology. (2022)18:530-544. https://doi.org/10.1007/s12024-022-00522-0 (SCIE,小类3区,2.456 . Published online: 19 September 2022.)
Xuebing Chen#, Jingshen Zhuang#, Qianling Chen, Luyao Xu, Xia Yue, Dongfang Qiao*. Polyvinyl chloride microplastics induced gut barrier dysfunction, microbiota dysbiosis and metabolism disorder in adult mice. Ecotoxicology and Environmental Safety.2022; 241,113809, 1-10. https://doi.org/10.1016/j.ecoenv.2022.113809 (SCIE,小类1区, 7.129, online 4 July 2022)
陶乐居, 曹文鑫, 陈为龙, 李宏春, 宋建伟, 乔东访*.他杀缢死法医学检验 2例[J]. 法医学杂志, 2022, 38(3): 331-333. doi:10.12116/j.issn.1004-5619.2021.410612(To cite:TAO L J,CAO W X,CHEN W L,et al. Forensic examination of homicide by hanging:Two case reports[J]. Fayixue Zazhi,2022,38(3):331-333.)(中文核心期刊, 发表时间:2022.06.25)
Xuebing Chen#, Jingshen Zhuang#, Qianling Chen, Luyao Xu, Xia Yue, Dongfang Qiao*. Chronic exposure to polyvinyl chloride microplastics induces liver injury and gut microbiota dysbiosis based on the integration of liver transcriptome profiles and full-length 16S rRNA sequencing data. Science of the Total Environment. 2022; 839,155984,1-13. http://dx.doi.org/10.1016/j.scitotenv.2022.155984 (SCIE,小类1区, 10.754, online 16 May 2022)
陈巧巧,陈龙,王婉婷,岳霞,乔东访*. 浅谈“法医病理学”教学的理论实践适应性[J]. 当代教育实践与教学研究,2022(20):99-101. (发表时间2022-11-01)
Xue-Bing Chen#, Dong Qu#, Qing Zhang, Xia Yue and Dong-Fang Qiao*. Might life-threatening acute pulmonary edema occur after using recombinant tissue plasminogen activator? A case report. BMC Neurology,2021; 21,346:1-4. (SCIE, 小类4区,2.356, online 9 September 2021 )https://doi.org/10.1186/s12883-021-02371-w
Xu Zhao#, Jiancong Lu#, Xuebing Chen#, Zhengxiang Gao, Cui Zhang, Chuanxiang Chen, Dongfang Qiao*, Huijun Wang*. Methamphetamine exposure induces neuronal programmednecrosis by activating the receptor- interacting protein kinase3 - related signalling pathway. The FASEB Journal. 2021;35:e21561.DOI: 10.1096/fj.202100188R(SCIE,小类2区,4.966, Accepted: 15 March 2021)
Chen Xuebing#, Qiu Feng#, Zhao Xu, Lu Jiancong, Tan Xiaohui, Xu Jingtao, Chen Chuanxiang, Zhang Fu, Liu Chao, Qiao Dongfang* and Wang Huijun*. Astrocyte-Derived Lipocalin-2 Is Involved in Mitochondrion-Related Neuronal Apoptosis Induced by Methamphetamine. ACS Chemical Neuroscience, 2020, 11, 1102−1116.DOI:1010.1021/acschemneuro.9b00559(SCIE,小类2区,4.486, Accepted: March 18, 2020)
陈雪冰,杜思昊, 卢健聪,谭晓辉,李冬日,岳霞,王起,王慧君*,乔东访*. 61 例儿童病毒性肺炎死亡案例回顾性分析. 法医学杂志,2020, 36(2):1-5. Doi:10.12116/j.issn.1004-5619.2020.01.00*
Du Si-Hao#; Zhang Wei#; Yue Xia; Luo Xiao-Qing; Tan Xiao-Hui; Liu Chao; Qiao Dong-Fang*; Wang Huijun*.Role of CXCR1 and Interleukin-8 in Methamphetamine-Induced Neuronal Apoptosis. Frontiers in Cellular Neuroscience, 2018, 12, 230:1-13. SCIE.DOI:10.3389/fncel.2018.00230(大类2区,3.921,published: 03 August 2018)
Du Si-Hao#; Qiao Dong-Fang#; Chen Chuan-Xiang; Chen Si; Liu Chao; Lin Zhoumeng; Wang Huijun*; Xie Wei-Bing*. Toll-Like Receptor 4 Mediates Methamphetamine-Induced Neuroinflammation through Caspase-11 Signaling Pathway in Astrocytes. Frontiers in Molecular Neuroscience, 2017, 10: 0-409. SCIE.DOI:10.3389/fnmol.2017.00409(大类2区,4.057)
Huang Weiye#, Xie Wei-Bing#, Qiao Dongfang #, Qiu Pingming #, Huang Enping, Li Bing, Chen Chuanxiang, Liu Chao, Wang Qi, Lin Zhoumeng, Wang Huijun *. Caspase-11 plays an essential role in Methamphetamine- Induced Dopaminergic Neuron Apoptosis. Toxicol Sci. 2015; 145(1): 68-79. SCIE. DOI:10.1093/toxsci/kfv014
Qiao Dongfang#; Xu Jingtao#; Le Cuiyun#; Huang Enping; Liu Chao; Qiu Pingming; Lin Zhoumeng; Xie Wei-Bing*; Wang Huijun*. Insulin-like growth factor binding protein 5 (IGFBP5) mediates methamphetamine-induced dopaminergic neuron apoptosis. Toxicology Letters, 2014, 230(3): 444-453. SCIE DOI:10.1016/j.toxlet.2014.08.010
Xia YUE (岳霞) # , Dongfang QIAO (乔东访) # , Aifeng WANG (王爱枫) , Xiaohui TAN (谭晓辉) , Yanhong LI (李艳红) ,Chao LIU (刘超) ,Huijun WANG (王慧君)*. CD200 Attenuates Methamphetamine-induced Microglial Activationand Dopamine Depletion. J Huazhong Univ Sci Technol [Med Sci], 2012, 32(3):415-421. DOI:10.1007/s11596-012-0072-0
2. 科研项目
国家自然科学基金面上项目:小胶质细胞参与的甲基苯丙胺对大鼠敏感脑区的炎性病理损伤机制(81172907),2012.01-2015.12,52万元,主持,已结题。
广东省自然科学基金项目:甲基苯丙胺中毒小胶质细胞 microRNAs 表达谱分析和机制研究(No.S2013010015473),2013.10-2015.10,10万元,主持,已结题。
广东省基础与应用基础研究基金项目:星形胶质细胞在METH神经炎症损伤中的调节作用(No. 2019A1515011987),2019.10-2022.9,10万元,主持,已结题。
广州市科技公关计划子项目:脑干损伤死亡法医学检验关键新方法研究(No. 2019030003),2019.07-2022-06,30万元,主持,已结题。
广东省自然科学基金面上项目:METH所致中枢神经系统炎症损伤中A20对星形胶质细胞异质性作用机制的研究(No. 2021A1515010909),2021.01-2023.12,10万元,主持,已结题。
国家自然科学基金-面上项目:METH所致中枢神经系统炎症损伤中TNFAIP3对星形胶质细胞异质性作用机制的研究(82271930),2023.01-2026.12,52万,主持,在研。
广东省基础与应用基础研究基金项目:METH暴露相关认知障碍中Ast异质性调控血脑屏障功能作用机制的研究(No.2024A1515013050),2024.01-2026.12,15万,主持,在研。
3. 教学项目
2025年广东省本科高校教学质量与教学改革工程项目,法医病理学实验教学示范中心,省级立项, 2025.01-2028.12,主持人,在研。
4. 成果奖励
2025年广东省本科教育教学优秀教学成果奖(高等教育-本科类)二等奖《以国家战略需求为导向的“四链融合”卓越法医人才培养体系构建与实践》,第三完成人;
2025年南方医科大学本科教育教学优秀教学成果奖(高等教育-本科类)一等奖《横向融汇纵向贯通 德法兼修 能力跃升:法医病理实践教学10年探索与创新实践》,第一完成人;
2024年南方医科大学第十三届中青年教师本科课程(设计)教学竞赛一等奖,法医病理学,课程负责人;
2023年南方医科大学教学优秀一等奖;
2017年南方医科大学教学优秀二等奖;
2003年广东省科学技术进步奖三等奖及2002年军队科学技术进步奖,第四完成人;
国家级、省级一流本科课程《法医病理学》,课程负责人。
广东省思政课程与课程思政改革示范团队,法医病理学课程教学团队,负责人。
第十届全国大学生基础医学创新研究暨实验设计论坛总决赛金奖(最佳学术奖)、优秀指导教师,指导教师。
第十一届全国大学生医学创新大赛暨“一带一路”国际竞赛校赛一等奖、复赛一等奖、决赛铜奖,指导教师。
第一届虚拟仿真实验创新大赛卓越奖,指导教师。
首届全国法医学本科技能竞赛个人一等奖、团体二等奖,指导教师。
5. 教材著作
副主编,高水平大学十四五"规划法医学专业精品教《法医病理学与法医毒理学
实践学习指》,武汉:华中科技大学出版社,2022
副主编,《法医病理学实例图鉴》,武汉:湖北科学技术出版社,2024
编委,全国高等教育医学数字化规划教材《法医学》,北京:人民军医出版社,2013
编委,全国高等学校法医学专业第五轮国家卫生计生委规划教材《法医毒理学》,北京:人民卫生出版社,2015
编委,卫生部“十二五”规划教材《法医学》,北京:人民卫生出版社,2016
编委,《生物安全丛书》,西安:西安交通大学出版社,2022
编委,全国司法鉴定继续教育培训实务《法医病理司法鉴定实务》,北京:科学出版社,2025
编委,全国高等学校法医学专业第六轮国家卫生计生委规划教材《法医毒理学》,北京:人民卫生出版社,待出版