姓名：朱波峰
电子邮箱：zhubofeng7372@126.com
工作单位：南方医科大学法医学院
职称：二级教授、研究员、主任法医师、博士生导师
学术任职：
教育部法医学专业教学指导委员会委员、中国遗传学会法医遗传学分会副主任委员、中国法医学会理事及法医物证专业委员会副主任委员、广东省司法鉴定协会副会长、广州市司法鉴定协会监事长、广东省精准医学应用学会法医学分会主任委员。国家级资质认定评审员和CNAS评审员、国家卫健委《毒品依赖和戒治重点实验室》学术委员会副主任委员、上海市法医学重点实验室第三届学术委员会委员、河北省法医学重点实验室学术委员会委员、广东省法医学转化工程技术研究中心学术委员会委员。《Human Genomics》杂志副主编，《Forensic Sciences Research》、《Journal of Forensic Science and Medicine》、《遗传》、《法医学杂志》、《中国法医学杂志》、《证据科学》等杂志的编委。
研究领域（方向）：
法医物证鉴识多组学创新研究、疑难复杂亲缘关系鉴定、人体表征分子鉴识、物证检材溯源基础和应用研究。
个人简介：
二级教授、研究员、主任法医师、博士生导师；南方医科大学法医学院院长、南方医科大学司法鉴定中心主任，国家自然科学基金杰出青年科学基金获得者、入选中组部、人社部万人计划科技创新领军人才、科技部和陕西省中青年科技创新领军人才、国家卫生健康突出贡献中青年专家、教育部新世纪优秀人才支持计划、广东省珠江学者特聘教授和医学领军人才、广东省最美科技工作者、广东省法医物证鉴识创新研究团队负责人。主持国家自然科学基金6项、重大项目课题和重点项目各1项，科技部重点研发课题2项。从事法医物证教学、科研和司法鉴定工作26年，发表SCI论文100多篇，申请技术发明专利12项，参编英文教材1本、专著1本；中文专著4部；规划教材2本，司法鉴定行业技术标准2部。曾荣获第十二届中国青年科技奖、省科学技术奖一等奖一项为第一完成人、二等奖二项。入选“2023全球前2%顶尖科学家”榜单。
科研项目：
1. 国家自然科学基金重大项目：转录组分子标记时相变化规律与组织离体时间推断研究（82293652），2023.01-2027.12，资助金额220万元，课题主持人，在研。
2. 国家自然科学基金重点项目：多源组学结合人工智能探索五类分子标记进行体液（斑）精准组织溯源的系统研究（81930055），2020.01-2024.12，资助金额297万元，项目主持人，在研。
3. 国家重点研发计划项目：面向公共法律服务的法医学智能化精准鉴识关键技术研究，2023.01-2026.12，资助金额102万元，课题主持人，在研。
4. 国家重点研发计划项目：*****技术研究（涉密），2022.01-2024.12，资助金额82万元，课题主持人，在研。
5. 中国工程院重点咨询研究项目子课题主持人：法医科学与社会治理法治化战略研究，2019.01-2020.12，资助金额30万，课题主持人，结题。
6. 国家自然科学基金面上项目：基于全基因组甲基化策略对体液（斑）DMRs进行深度挖掘、验证和法医学应用的系统研究（81772031），2018.01-2021. 12，资助金额55万，项目主持人，结题。
7. 国家杰出青年科学基金：法医学（81525015），2016.01-2020.12，资助金额400万，项目主持人，结题。
科研论文：
1. Chen M, Chen C , Li N, Su Y , Cui W , Huang Y, Cai M, Zhu B, Forensic efficiency evaluation of a mtDNA whole genome sequencing system constructed with long fragment amplification strategy on DNA nanoball sequencing platform, Forensic Sci Int Genet, 2024,73:103126
2. Chen X, Xu H, Lin Y, Zhu B. Forensic stability evaluation of selected miRNA and circRNA markers in human bloodstained samples exposed to different environmental conditions. Forensic Sci Int. 2024:362:112148
3. Mei S, Cai M, Lei F, Wang X, Yuan X, Lin Y, Zhu B. Revealing microbial community characteristics in healthy human, cat and canine salivas and looking for species-specific microbes. Int J Legal Med. 2024 Jul 10. doi: 10.1007/s00414-024-03277-1.
4. Liu F, Zhu B, An Y, Zhou Z, Xiong P, Li X, Mi Y, He T, Chen F, Wu B. Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects. Int J Oral Sci. 2024;16(1):53.
5. Wang M, Huang Y, Liu K, Wang Z, Zhang M, Yuan H, Duan S, Wei L, Yao H, Sun Q, Zhong J, Tang R, Chen J, Sun Y, Li X, Su H, Yang Q, Hu L, Yun L, Yang J, Nie S, Cai Y, Yan J, Zhou K, Wang C; 10K_CPGDP Consortium; Zhu B, Liu C, He G. Multiple Human Population Movements and Cultural Dispersal Events Shaped the Landscape of Chinese Paternal Heritage. Mol Biol Evol. 2024; 41(7): msae122.
6. Liu L, Wang C, Wang H, Miao L, Xie T, Tian Y, Li X, Huang Y, Zeng X, Zhu B. Identification of the circRNA-miRNA-mRNA network for treating methamphetamine-induced relapse and behavioral sensitization with cannabidiol. CNS Neurosci Ther. 2024; 30(5):e14737.
7. Zhou Y, Wang J, Wu B, Zhu B. Rapid determination of furazolidone residues in animal foods by time-resolved fluorescence immunochromatography. Food Chem. 2024; 445:138711.
8. Ji Z, Xing Y, Li J, Feng X, Yang F, Zhu B, Yan J. Male-specific age prediction based on Y-chromosome DNA methylation with blood using pyrosequencing. Forensic Sci Int Genet. 2024; 71:103050.
9. Chen C, Guo Y, Fang Y, Shi J, Meng H, Qu L, Zhang X, Zhu B. The maternal phylogenetic insights of Yunnan Miao group revealed by complete mitogenomes. Gene. 2024; 901:148046.
10. Yuan X, Wang X, Lan Q, Li S, Lin Y, Zhao M, Xu H, Lei F, Shen C, Zhu B. Using two self-developed InDel panels to explore forensic traits and ancestral components in the Hui group. Genomics. 2024;116(1):110756.
11. Lan Q, Cai M, Xu H, Bai X, Shen C, Zhu B. Developmental validation of a custom-designed Multi-InDel panel: A five-dye multiplex amplification system for challenging DNA samples. Electrophoresis. 2024; 45(5-6):489-504.
12. Cai M, Lei F, Chen M, Lan Q, Wu X, Mao C, Shi M, Zhu B. Systematic analyses of AISNPs screening and classification algorithms based on genome-wide data for forensic biogeographic ancestry inference. Forensic Sci Int. 2024; 357:111975.
13. Mei S, Wang X, Lei F, Lan Q, Cai M, Zhu B. Focus on studying the effects of different exposure durations on the microbial structures and characteristics of three types of body fluids. Forensic Sci Int. 2024; 356:111949.
14. Cai M, Lei F, Liu Y, Wang X, Wang H, Xie W, Yang Z, Yang S, Zhu B. Joint application of A-InDels and miniSTRs for forensic personal, full and half sibling identifications, and genetic differentiation analyses in two populations from China. BMC Genomics. 2024;25(1):329.
15. Liu L, Li S, Cui W, Fang Y, Mei S, Chen M, Xu H, Bai X, Zhu B. Ancestry analysis using a self-developed 56 AlM-InDel loci and machine learning methods. Forensic Sci Int. 2024: 361:112065.
16. Fang Y, Chen M, Zhu B. Construction and evaluation of in-house methylation-sensitive SNaPshot system and three classification prediction models for identifying the tissue origin of body fluid. J Zhejiang Univ Sci B. 2023; 24(9):839-852.
17. Chen J, Lin J, Hu Y, Ye M, Yao L, Wu L, Zhang W, Wang M, Deng T, Guo F, Huang Y, Zhu B, Wang D. RNADisease v4.0: an updated resource of RNA-associated diseases, providing RNA-disease analysis, enrichment and prediction. Nucleic Acids Res. 2023;51(D1):D1397-D1404.
18. Cui W, Chen M, Yang Y, Cai M, Lan Q, Xie T, Zhu B. Applications of 1993 single nucleotide polymorphism loci in forensic pairwise kinship identifications and inferences. Forensic Sci Int Genet. 2023; 65:102889.
19. Chen X, Xu H, Zhu B. Forensic validation of a combined analysis of mRNA and miRNA markers for precise tissue origin inferences of five kinds of body fluids by RT-qPCR. Electrophoresis. 2023; 44(21-22):1714-1724.
20. Fang Y, Chen M, Cai M, Lei F, Zhu B. Selection and validation of a novel set of specific differential methylation markers and construction of a random forest prediction model for the accurate tissue origin identifications of body fluids involving young and middle-aged group of Chinese Han population. Int J Legal Med. 2023;137(5):1395-1405.
21. Lan Q, Cai M, Xu H, Bai X, Shen C, Zhu B. Developmental validation of a custom-designed Multi-InDel panel: A five-dye multiplex amplification system for challenging DNA samples. Electrophoresis. 2024; 45(5-6):489-504
22. Lan Q, Lin Y, Wang X, Yuan X, Shen C, Zhu B. Targeted sequencing of high-density SNPs provides an enhanced tool for forensic applications and genetic landscape exploration in Chinese Korean ethnic group. Hum Genomics. 2023; 17(1):107.
23. Wang H, Kang B, Gao Y, Zhang M, Jiang J, Su J, Zhang B, Zhu B, Liao S. Construction and evaluation of a novel set of 90 microhaplotypes for forensic applications using NGS technology. Forensic Sci Int. 2023; 353: 111848.
24. Cai M, Li S, Zhang X, Xie W, Shi J, Yuan X, Yao J, Zhu B. Ancestral Information Analysis of Chinese Korean Ethnic Group via a Novel Multiplex DIP System. J Mol Evol. 2023; 91(6):922-934.
25. Zhou Y, Bo F, Tian T, Wu B, Zhu B. Excessive addition split peak formed by the non-templated nucleotide addition property of Taq DNA polymerase after PCR amplification. Front Bioeng Biotechnol. 2023; 11:1180542.
26. Lan Q, Li S, Cai M, Lei F, Shen C, Zhu B. A self-developed AIM-InDel panel designed for degraded DNA analysis: Forensic application characterization and genetic landscape investigation in the Han Chinese population. Genomics. 2023; 115(3):110620.
27. Liu Y, Mei S, Jin X, Zhao M, Zhu B. Independent development and validation of a novel six-color fluorescence multiplex panel including 61 diallelic DIPs and 2 miniSTRs for forensic degradation sample. Electrophoresis. 2022; 43(13-14):1423-1437.
28. Mei S, Zhao M, Liu Y, Zhao C, Xu H, Fang Y, Zhu B. Evaluations and comparisons of microbial diversities in four types of body fluids based on two 16S rRNA gene sequencing methods. Forensic Sci Int. 2022; 331:111128.
29. Jin XY, Liu YF, Cui W, Chen C, Zhang XR, Huang J, Zhu BF. Development a multiplex panel of AISNPs, multi-allelic InDels, microhaplotypes, and Y-SNP/InDel loci for multiple forensic purposes via the NGS. Electrophoresis. 2022; 43(4):632-644.
30. Fang Y, Mei S, Zhang Y, Teng R, Tai Y, Zhu B. Forensic and genetic landscape explorations of Chinese Kyrgyz group based on autosomal SNPs, Y-chromosomal SNPs and STRs. Gene. 2022; 832:146552.
31. Zhang X, Shen C, Jin X, Guo Y, Xie T, Zhu B. Developmental validations of a self-developed 39 AIM-InDel panel and its forensic efficiency evaluations in the Shaanxi Han population. Int J Legal Med. 2021; 135(4):1359-1367.
32. Zhang W, Zhou R, Yang Y, Peng S, Xiao D, Kong T, Cai X, Zhu B. Aptamer-mediated synthesis of multifunctional nano-hydroxyapatite for active tumour bioimaging and treatment. Cell Prolif. 2021; 54(9):e13105.
33. Chen C, Jin X, Zhang X, Zhang W, Guo Y, Tao R, Chen A, Xu Q, Li M, Yang Y, Zhu B. Comprehensive insights into forensic features and genetic background of Chinese Northwest Hui group using six distinct categories of 231 molecular markers. Front Genet. 2021; 12:705753.
34. Zhou Y, Lan Q, Fang Y, Guo Y, Xie T, Du W, Zhu B. Detection and analysis of the cause of false-tetra-allelic patterns of locus D10S1435 at the sequence level. Int J Legal Med. 2020;134(3):833-843.
35. Kong T, Zhou R, Zhang Y, Hao L, Cai X, Zhu B. AS1411 aptamer modified carbon dots via polyethylenimine-assisted strategy for efficient targeted cancer cell imaging. Cell Prolif. 2020; 53(1):e12713.
36. Chen C, Li Y, Tao R, Jin X, Guo Y, Cui W, Chen A, Yang Y, Zhang X, Zhang J, Li C, Zhu B. The genetic structure of Chinese Hui ethnic group revealed by complete Mitochondrial genome analyses using massively parallel sequencing. Genes (Basel). 2020; 11(11):1352
37. Zhou Y, Xie T, Guo Y, Mei X, Lan Q, Fang Y, Jin X, Zhu B. The validation study of a novel assay with 30 slow and moderate mutation Y-STR markers for criminal investigation and database applications. Int J Legal Med. 2020; 134(2):491-499.
38. Jin XY, Cui W, Chen C, Guo YX, Zhang XR, Xing GH, Lan JW, Zhu BF. Developing and population analysis of a new multiplex panel of 18 microhaplotypes and compound markers using next generation sequencing and its application in the Shaanxi Han population. Electrophoresis. 2020; 41(13-14):1230-1237.
39. Cui W, Jin X, Guo Y, Chen C, Zhang W, Wang Y, Lan J, Zhu B. Development and validation of a novel five-dye short tandem repeat panel for forensic identification of 11 species. Front Genet. 2020; 11:1005.
40. Xie T, Guo Y, Chen L, Fang Y, Tai Y, Zhou Y, Qiu P, Zhu B. A set of autosomal multiple InDel markers for forensic application and population genetic analysis in the Chinese Hui group. Forensic Sci Int Genet. 2018; 35:1-8.
