一、基本信息
姓名:周超颖
职称:讲师
联系邮箱:zhouchaoying100@163.com,zhouchao@smu.edu.cn
联系电话:020-61648553
二、学习经历
2005.9-2010.7 河北北方学院,医学检验专业,学士
2010.9-2016.7 南方医科大学,免疫学专业(硕博连读),博士
2016.7-2019.7 南方医科大学,生物学学科,博士后
三、承担教学任务
1、《基因工程学》
2、《生物技术综合实验一》
3、《临床免疫学检验》
4、《临床生物化学检验》
5、《临床微生物学检验》
四、主要研究方向
结核感染免疫:
1、MAIT细胞在抗结核感染免疫中的效应与机制
2、抗原特异TCR基因修饰T细胞的抗结核感染免疫
五、主要学术任职
广东省免疫学会会员
七、主要获奖情况
1. 中国博士后科学基金面上一等资助,中国博士后基金委,2016;
2. 博士研究生国家奖学金,中华人民共和国教育部,2015;
3. 优秀毕业研究生,南方医科大学,2016;
4. 优秀研究生,南方医科大学,2015;
5. 优秀研究生,南方医科大学,2012
八、 代表性论文
1. Zhou CY, Wang RN, Wen Q, He WT, Zhang SM, Du XL, Yang JH, Ma L. Alanine mutagenesis in the CDR3 of the MTB and HIV-1 peptide-bispecific TCR beta chain affects ligand recognition. Front Immunol. 2017,8:983(IF 7.561)
2. Zhou CY, Wen Q, Chen XJ, Wang RN, He WT, Zhang SM, Du XL, Ma L. Human CD8+ T cells transduced with an additional receptor bispecific for both Mycobacterium tuberculosis and HIV-1 recognize both epitopes. J Cell Mol Med. 2016, 20(10): 1984-1998(IF 5.310)
3. Wen Q#, Zhou CY#, Xiong WJ, Su J, He JC, Zhang SM, Du XL, Liu SD, Wang JJ, Ma L. MiR-381-3p regulates the antigen-presenting capability of dendritic cells and represses antituberculosis cellular immune responses by targeting CD1c. J Immunol. 2016, 197(2): 580-589(IF 5.422)
4. Zhou X#, Lie L#, Liang Y, Xu H, Zhu B, Huang YQ, Zhang LJ, Zhang ZL, Li QN, Wang Q, Han ZY, Huang YL, Liu HL, Hu SF, Zhou CY, Wen Q, Ma L. GSK-3α/β activity negatively regulates MMP-1/9 expression to suppress Mycobacterium tuberculosis infection. Front Immunol. 2022,12:752466(IF 7.561)
5. Wen Q#, Li YF#, Han ZY, Liu HL, Zhang SM, Chen YX, He JC, Du XL, Fu YL, Zhang LJ, Zhang ZL, Huang YL, Zhou XY, Zhou CY, Hu SF, Ma L. β-Arrestin 2 regulates inflammatory responses against Mycobacterium tuberculosis infection through ERK1/2 signaling. J Immunol. 2021,206(11):2623-2637(IF 5.422)
6. Zhou XY#, Zhang LJ#, Lie LM, Zhang ZL, Zhu B, Yang JH, Gao YC, Li PF, Huang YQ, Xu H, Li YF, Du XL, Zhou CY, Hu SF, Wen Q, Zhong XP, Ma L. MxA suppresses TAK1-IKKalpha/beta-NF-kappaB mediated inflammatory cytokine production to facilitate Mycobacterium tuberculosis infection. J Infect. 2020,81(2):231-241(IF 6.072)
7. Zhou XY#, Yang JH#, Zhang ZL, Zhang LJ, Lie LM, Zhu B, Xu L, Gao YC, Du XL, Huang YQ, Wang RN, Liu HL, Li YF, Hu SF, Zhou CY, Wen Q, Pan QW, Ma L. Interferon regulatory factor 1 eliminates mycobacteria by suppressing p70 S6 kinase via mechanistic target of rapamycin signaling. J Infect. 2019, 79(03): 262-276(IF 6.072)
8. Hu SF, Du XL, Huang YL, Fu YL, Yang YL, Zhan XX, He WT, Wen Q, Zhou XY, Zhou CY, Zhong XP, Yang JH, Xiong WJ, Wang RN, Gao YC, Ma L. NLRC3 negatively regulates CD4+ T cells and impacts protective immunity during Mycobacterium tuberculosis infection. PLoS Pathog. 2018,14(8):e1007266(IF 6.823)