姓名:田立文
职称:副教授,博士
联系邮箱:lwtian@smu.edu.cn
主要招生方向:药物化学、工业药学
教育经历:
2006/9 - 2011/7,中国科学院昆明植物研究所,药物化学,理学博士
2002/9 - 2006/6,湖北中医药大学,药物制剂,理学学士
工作经历:
2014/6 - 至今,南方医科大学,药学院,讲师,副教授
2019/1-2020/12,香港大学,化学系,博士后
2012/2 - 2013/7,澳大利亚格里菲斯大学,药物发现研究所,Research Fellow
2011/8 - 2012/1,中国科学院昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,助理研究员
研究兴趣:
1) 真菌中新颖天然产物的分离与鉴定;
2) 活性天然产物的药物化学研究。
近5年代表性论文:
1.Yuantao Han, Yuanyuan Cheng, Li-Wen Tian*. Semisynthesis of 22,25-epoxylanostane triterpenoids: structure eevision and protective effects against oxygen-glucose deprivation/reoxygenation injury in H9c2 cells. J. Nat. Prod. 2023, 86(2), 406-415.
2.Xiao Feng#, Baoping Xie#, Yuantao Han, Zhiying Li, Yuanyuan Cheng*, Li-Wen Tian*. Bisbenzylisoquinoline alkaloids from Plumula Nelumbinis inhibit vascular smooth muscle cells migration and proliferation by regulating the ORAI2/Akt pathway. Phytochemistry 2023, 211, 113700.
3.Yu-Ting Li, Zhen Zhang, Yunjing Feng, Yuanyuan Cheng, Shuyuan Li, Can Li, Li-Wen Tian*. Cardioprotective 22-hydroxylanostane triterpenoids from the fruiting bodies of Phellinus igniarius. Phytochemistry 2021, 191, 112907.
4.Yu-Ting Li#, Chan Yang#, Yan Wu#, Jun-Jiang Lv, Xiao Feng, Xiaofei Tian, Zhengzheng Zhou, Xiaoyan Pan*, Shuwen Liu*, Li-Wen Tian*. Axial chiral binaphthoquinone and perylenequinones from the stromata of Hypocrella bambusae are SARS-CoV-2 entry inhibitors J. Nat. Prod. 2021, 84(2), 436-443.
5.Wan-Shan Li, Han-Bo Hu, Zhong-Hui Huang, Ren-Jie Yan, Li-Wen Tian*, Jun Wu*. Phomopsols A and B from the mangrove endophytic fungus Phomopsis sp. xy21: Structures, neuroprotective effects, and biogenetic relationships. Org. Lett. 2019, 21(19), 7919-7922.