学术任职
现任中国毒理学会青年委员会常务委员、中国环境诱变剂学会生物标志物专业委员会常务委员、广东省毒理学会常务理事、广东省毒理学青年委员会常务委员等；担任国家自然科学基金、广东省自然科学基金、浙江省自然科学基金、湖南省自然科学基金等项目通讯评审人；担任ACS Nano，Advanced Science，Gut Microbes，J Hazard Mater，Pharmacol Res，Phytomedicine等环境科学、毒理学、药学学科领域TOP期刊审稿人。担任Toxics杂志（ISSN 2305-6304，IF = 4.1）客座主编，Special Issue: Developmental Toxicity Mechanism of Emerging Contaminants (ECs). https://www.mdpi.com/journal/toxics/special_issues/9HETBWVHFA.
所属科室
毒理学系
研究方向
环境与健康、发育毒性、药物毒理
科研项目
先后主持/主要参与国家级、省部级科研项目多项。目前在研科研项目包括：国家自然科学基金面上项目2项（2022-2025、2026-2029）、广东省自然科学基金面上项目1项（2024-2026）、广州市科技菁英“领航”项目1项（2025-2027）。
代表论文（通讯/共同通讯作者，近5年代表论文）
1. Zhang K, Yang J, Chen L, He J, Qu D, Zhang Z, Liu Y, Li X, Liu J, Li J, Xie X*, Wang Q*. Gut Microbiota Participates in Polystyrene Microplastics-Induced Hepatic Injuries by Modulating the Gut-Liver Axis. ACS Nano. 2023 Aug 8;17(15):15125-15145. （IF2023=17.1，中科院小类I区，ESI高被引文章）
2. Zhang K, Chen L, Yang J, Liu J, Li J, Liu Y, Li X, Chen L, Hsu C, Zeng J, Xie X*, Wang Q*. Gut microbiota-derived short-chain fatty acids ameliorate methamphetamine-induced depression- and anxiety-like behaviors in a Sigmar-1 receptor-dependent manner. Acta Pharmaceutica Sinica B. 2023 Dec;13(12):4801-4822.（IF2023=14.5，中科院小类I区）
3. Chen L, Zhang K, Liu J, Li X, Liu Y, Ma H, Yang J, Li J, Chen L, Hsu C, Zeng J, Xie X*, Wang Q*. The role of the microbiotaegutebrain axis in methamphetamine-induced neurotoxicity: Disruption of microbial composition and short-chain fatty acid metabolism. Acta Pharm Sin B. 2024 Nov;14(11):4832-4857. （IF2024=14.8，中科院小类I区）
4. Yang JZ, Zhang KK, Hsu C, Miao L, Chen LJ, Liu JL, Li JH, Li XW, Zeng JH, Chen L, Li JH, Xie XL*, Wang Q*. Polystyrene nanoplastics induce cardiotoxicity by upregulating HIPK2 and activating the P53 and TGF-β1/Smad3 pathways. J Hazard Mater 2024 Aug 5:474:134823. （IF2024=12.2，中科院小类I区）
5. Xu LL, Chen YK, Zhang QY, Chen LJ, Zhang KK, Li JH, Liu JL, Wang Q*, Xie XL*. Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA. Sci Total Environ. 2022 May 10;820:153281. （IF2021=10.753，中科院小类I区）
6. Xu LL, Zhang QY, Chen YK, Chen LJ, Zhang KK, Wang Q, Xie XL*. Gestational PCB52 exposure induces hepatotoxicity and intestinal injury by activating inflammation in dam and offspring mice: A maternal and progeny study. Environ Pollut. 2022 Nov 15;313:120186. （IF2021=9.988，中科院小类I区）
7. Li JH, Liu JL, Li XW, Yang JZ, Liu Y, Wang H, Chen LJ, Zhang KK, Xie XL*, Wang Q*. Gut microbiota mediates prenatal METH exposure-induced anxiety- and depression-like behaviors by modulating the Wnt signaling pathway. Brain Behavior and Immunity. 2025 Nov, 130, 106112. （IF2024=7.6，中科院小类I区）
8. Zhang QY, Xu LL, Zhong MT, Chen YK, Lai MQ, Wang Q*, Xie XL*. Gestational GenX and PFOA exposures induce hepatotoxicity, metabolic pathway, and microbiome shifts in weanling mice. Sci Total Environ. 2024 Jan 10, 907: 168059.（IF2023=8.2，中科院小类II区）
9. Yang JZ, Zhang KK, Liu Y, Li XW, Chen LJ, Liu JL, Li JH, Chen L, Hsu C, Zeng JH, Xie XL*, Wang Q*. Epigallocatechin-3-gallate ameliorates polystyrene microplastics-induced anxiety-like behavior in mice by modulating gut microbe homeostasis. Sci Total Environ. 2023 Sep 20;892:164619.（IF2023=9.8，中科院小类II区）
10. Zhang QY, Lai MQ, Chen YK, Zhong MT, Gi M, Wang Q, Xie XL*. Inulin alleviates GenX-induced intestinal injury in mice by modulating the MAPK pathway, cell cycle, and cell adhesion proteins. Environ Pollut. 2024 Dec 1:362:124974.（IF2024=7.6，中科院小类II区）
