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毛丽梅

职称:三级教授,博士生导师,博士后合作导师

职务:营养与食品卫生学系主任

通讯地址:南方医科大学公共卫生学院

办公电话:020-61648328

E-mail: mlm912@163.com

扩展字段01 职称:三级教授,博士生导师,博士后合作导师 扩展字段02 职务:营养与食品卫生学系主任
扩展字段03 通讯地址:南方医科大学公共卫生学院 扩展字段04 办公电话:020-61648328
扩展字段05 E-mail: mlm912@163.com

学术任职

曾任中国营养学会理事、中国营养学会妇幼营养分会副主任委员 、广东省营养学会副理事长、广东省营养学会公共营养分会副主任委员、现任中国营养学会妇幼营养分会常务委员,广东省健康管理学会食品安全与营养健康专业委员会副主任委员

最高学历

华中科技大学同济医学院营养与食品卫生专业博士研究生/博士学位

研究方向

1. 妇幼营养与健康; 2. 膳食营养与慢性病

讲授课程

营养与食品卫生学、医学营养学、食品标准与法规等。

科研项目

主持国家级项目(国自然4项,国家科技支撑计划1项):

(1) 国家自然科学基金面上项目《EPADHA经调节肌源性IL-6表达改善脂质代谢紊乱的作用及机制研究(8207120920)》,2021.01-2024.1253万元,主持,在研;

(2) 国家自然科学基金面上项目《EPADHA调节胰岛素抵抗的作用差异及GPR120/PPARγ介导的机制研究(81773425)》,2018.01-2021.1255万元,主持,已结题;

(3) 国家自然科学基金面上项目《膳食n6/n3脂肪酸构成对脂联素表达的调节及CDK5/PPARγ介导的机制研究(81273072)》,2013.01-2016.1270万元,主持,已结题;

(4) 国家自然科学基金面上项目《adiponectin及其受体表达的营养调节研究(30571561)》,2006.01-2008.1225万元,主持,已结题;

(5) “十一五”国家科技支撑计划(分题)《我国华南地区妇女产褥期膳食营养干预研究(2008BA158B07)》,2008.12-2010.1232万元,主持,已结题;

主持省部级课题项目(2项):

(1) 妇幼卫生保健项目农村贫困地区扶贫工作研究评估子项目(卫生部) 2001.624.3万,主持,已结题;

(2) 广东省高校人才引进项目《脂肪酸构成对脂联素及其受体表达的影响及机制》,2009.01-2011.1220万元,主持,已结题;

主持横向课题(12项):

(1) 汤臣倍健营养科学研究基金《鱼油干预对中老年人心血管风险指标影响的随机对照研究》,2022/10/01-2024/09/30,主持,在研;

(2) 汤臣倍健营养科学研究基金《鱼油干预对中老年人血脂、免疫功能及炎性因子水平的影响(TY0120902)》,2012.11-2015.4 38.6万元,主持,已结题;

(3) 中国营养学会营养科研项目基金—帝斯曼专项营养基金《孕妇长链多不饱和脂肪酸水平与胎儿生长发育及其免疫功能关系研究》,2013.01-2014.0615万元,主持,已结题;

(4) 中国营养学会妇幼营养分会《孕期体重增长适宜值的多中心队列研究》 ,2012-2014,主持,已结题;

(5) 深圳市孕期体重增长适宜值队列研究. 达能婴幼儿营养品(香港)有限公司. 2013-2014,主持,已结题;

(6) 中国营养学会妇幼营养分会《产妇膳食营养状况资料综述和现状调查》,2003.12

(7) 达能营养基金《妇女产媷期饮食、行为习惯与健康关系研究(DIC 2002-06)》,2002.01-2003.1216万元,主持,已结题;

(8) 光彩多维珍珠牌钙胶囊研究. 武汉同和生物技术有限公司,2004.6

(9) 天年牌多肽蛋白粉免疫功能实验. 武汉天天好生物制品有限公司,2004.9

(10)深海鱼油卵磷脂辅助降血脂功能. 广州市佰健生物工程有限公司 2004.5

(11)同济世纪牌金奥泰胶囊研究. 武汉同济世纪生物工程有限公司 2004.12

(12)一牌傲骨颗粒增加骨密度功能. 江西一传生命科技有限公司 2005.2

(13)信健牌深海鱼油软胶囊动物毒理功能、人体功能实验. 广州市佰健生物工程有限公司 2005.10

代表论文


1. Wenting Wei#, Siyan Yu, Huanting Zeng, Weifeng Tan, Manjiang Hu, Jie Huang.Xudong Li, Limei Mao(*). Docosahexaenoic and eicosapentaenoic acids promote the accumulation ofbrowning-related myokines via calcium signaling in insulin-resistant mice. Journal of Nutrition. 2024 Feb 15:S0022-3166(24)00102-0. doi: 10.1016/j.tjnut.2024.02.016. Epub ahead of print.

2. Weifeng Tan#, Lianzhi Mao#, Siyan Yu, Jie Huang, Qunying Xie, Manjiang Hu, Limei Mao(*).DHA and EPA improve liver IR in HFD-induced IR mice through modulating the gut microbiotas-LPS-liver axis. Journal of Functional Foods. 2024 JAN. DOI10.1016/j.jff.2023.105917

3. Siyan Yu#, Qunying Xie#, Weifeng Tan, Manjiang Hu, Guiling Xu, Xiao Zhang, Guanghang Xie, Limei Mao(*). Different ratios of DHA/EPA reverses insulin resistance by improving adipocyte dysfunction and lipid disorders in HFD-induced IR mice. Food Function. 2023 Jan 5. doi: 10.1039/d2fo02686d. Epub ahead of print.

4. Wenting Wei#, Manjiang Hu#, Jie Huang, Siyan Yu, Xudong Li, Yanhui Li, Limei Mao(*). Anti-obesity effects of DHA and EPA in high fat-induced insulin resistant mice. Food Function. 2021 Feb 21;12(4):1614-1625.

5. Ying Chen(#), Yuting Qin, Zhiwei Zhang, Shaoming Huang, Changya Jiao, Zheqing Zhang, Wei Bao, Limei Mao(*). Association of the low-carbohydrate dietary pattern with postpartum weight retention in women. Food Function. 2021 Nov 1;12(21):10764-10772.

6. Yuting Qin(#), Changya Jiao, Shaoming Huang, Yanhui Li, Zheqing Zhang, Wei Bao, Limei Mao(*). "Zuòyuèzi" dietary and behavioural associations with maternal health among puerperal women in South China. Asia Pacific Journal of Clinical Nutrition. 2021 Jun;30(2):291-302.

7. Yuting Qin(#), Ying Chen, Zhiwei Zhang, Shaoming Huang, Changya Jiao, Zheqing Zhang, Limei Mao(*). Associations of dietary inflammatory potential with postpartum weight change and retention: Results from a cohort study. Obesity (Silver Spring). 2021 Oct;29(10):1689-1699.

8. Yuanhuan Wei(#), Jingjing Liang, Yixiang Su, Jue Wang, William Kwame Amakye, Jianliang Pan, Xinwei Chu, Bingjie Ma, Yanyan Song, Yan Li, Limei Mao(*), Zheqing Zhang(*). The associations of the gut microbiome composition and short-chain fatty acid concentrations with body fat distribution in children. Clinical Nutrition. 2021 May;40(5):3379-3390.

9. Jufeng Ye(#), Xiangdong Wang, Ke Wang, Yudi Deng, Yichao Yang, Rufida Ali, Feilong Chen, Zijian Wu, Wenzhen Liao(*), Limei Mao(*). A novel polysaccharide isolated from Flammulina velutipes, characterization, macrophage immunomodulatory activities and its impact on gut microbiota in rats. Journal of Animal Physiology and Animal Nutrition (Berl). 2020 Mar;104(2):735-748.

10. Liping Ma(#), Qinggui Lu, Jingyi Ouyang, Jie Huang, Shaoming Huang, Changya Jiao, Zheqing Zhang, Limei Mao(*). How are maternal dietary patterns and maternal/fetal cytokines associated with birth weight? A path analysis. The British Journal of Nutrition. 2019 May;121(10):1178-1187.

11. Jue Wang(#), Jialiang Pan(#), Hengying Chen, Yan Li, William Kwame Amakye, Jingjing Liang, Bingjie Ma, Xinwei Chu(*), Limei Mao(*), Zheqing Zhang(*). Fecal Short-Chain Fatty Acids Levels Were Not Associated With Autism Spectrum Disorders in Chinese Children: A Case-Control Study. Frontiers in Neuroscience. 2019 Nov 29;13:1216.

12. William Kwame Amakye(#), Zheqing Zhang, Yuanhuan Wei, Nitin Shivappa, James R Hebert, Jue Wang, Yixiang Su, Limei Mao(*). The relationship between dietary inflammatory index (DII) and muscle mass and strength in Chinese children aged 6-9 years. Asia Pacific Journal of Clinical Nutrition. 2018;27(6):1315-1324.

13. Jia Song(#), Manjiang Hu(#), Cheng Li(#), Bo Yang, Qing Ding, Chunhong Wang, Limei Mao(*). Dose-dependent effects of fish oil on cardio-metabolic biomarkers in healthy middle-aged and elderly Chinese people: a double-blind randomized controlled trial. Food Function. 2018 Jun 20;9(6):3235-3243.

14. Jia Song(#), Cheng Li, Yushan Lv, Yi Zhang, William Kwame Amakye, Limei Mao(*). DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARγ and its phosphorylation at Ser273 in 3T3-L1 adipocytes. Nutrition & Metabolism (London). 2017 Aug 11;14:52.

15. Jie-Hua Chen(#), Jia Song(#), Yan Chen, Qiang Ding, Anfang Peng, Limei Mao(*). The Effect of Vegan Protein-Based Diets on Metabolic Parameters, Expressions of Adiponectin and Its Receptors in Wistar Rats. Nutrients. 2016 Oct 18;8(10):643.

16. Zhe-Qing Zhang(#), Qing-Gui Lu, Jie Huang, Chang-Ya Jiao, Shao-Ming Huang, Limei Mao(*). Maternal and cord blood adiponectin levels in relation to post-natal body size in infants in the first year of life: a prospective study. BMC Pregnancy Childbirth. 2016 Jul 27;16(1):189.

17. Jie-Hua Chen(#), Caiqun Ouyang(#), Qiang Ding, Jia Song, Wenhong Cao, Limei Mao(*). A Moderate Low-Carbohydrate Low-Calorie Diet Improves Lipid Profile, Insulin Sensitivity and Adiponectin Expression in Rats. Nutrients. 2015 Jun 11;7(6):4724-38.

18. Xuefeng Yang(#), Yi Zhang, Jieyi Lin, Anfang Pen, Chenjiang Ying, Wenhong Cao, Limei Mao(*). A lower proportion of dietary saturated/monounsaturated/polyunsaturated fatty acids reduces the expression of adiponectin in rats fed a high-fat diet. Nutrition Research. 2012 Apr;32(4):285-91.

19. Nian Liu(#), Limei Mao(*), Xiufa Sun, Liegang Liu, Ping Yao, Banghua Chen. The effect of health and nutrition education intervention on women's postpartum beliefs and practices: a randomized controlled trial. BMC Public Health. 2009 Feb 1;9:45. ial

影响因子4.5 医学2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL Nian Liu(#), Limei Mao(*), Xiufa Sun, Liegang Liu, Banghua Chen, Qiang Ding. Postpartum practices of puerperal women and their influencing factors in three regions of Hubei, China. BMC Public Health. 2006 Nov 7;6:274.


教材著作

主编国家级实验教学示范中心教材《食品安全综合实习指导》,参编《临床营养学》、《妇幼营养学》、《公共卫生法律制度与监督》等国家级规划教材8部。参编“中国孕期、哺乳期妇女和0-6岁儿童膳食指南”等。


成果奖励

获省级科技进步二等奖(4)、三等奖(3)各一项、市级科技进步二等奖(4)一项。获2005年度“亨氏杯”中国婴幼儿营养事业成就奖三等奖。获评南方医科大学第七届优秀教师。