学术任职
广东省预防医学会流行病学专业委员会青年委员会常务委员;广东省预防接种异常反应调查诊断专家组专家 (2022.11-2026.11)
最高学历
博士
研究方向
长期从事病毒性腹泻病原学、分子流行病学和抗病毒药物方向研究
讲授课程
留学生本科、援外公共卫生硕士《Epidemiology》全英文教学,并获得2022-2023学年援外公共卫生硕士项目课程《Epidemiology: Principles and Methods》,被学生评为“年度最受欢迎课程”
科研项目
1. 广东省科技厅重点领域研发项目(子课题五),华南地区主要流行人类病毒模式小鼠资源库的建立及评估应用(华南地区高发肠道感染病毒小鼠模型的开发与应用平台建设),2022B11110200002,2022/07-2025/06,总经费1000万元(子课题五经费100万元),子课题负责人。
2. 广东省自然科学基金面上项目, 基于自然人群队列诺如病毒基因型更迭的群体免疫机制研究(2019A1515010951), 2020/01-2022/12, 10万元,主持。
3. 国家自然科学基金面上项目,GII.4型诺如病毒全人广谱中和单抗及其保守表位研究(31771007),2018/01-2021/12, 60万元,主持。
4. 广州市科技计划项目产学研协同创新重大专项民生科技研究专题,201604020111,特异性IgY微胶囊防治诺如/轮状病毒腹泻的成药性研究,2016/04-2019/03,100万元,结题,主持。
5. 南方医科大学科研启动计划基础研究前期启动项目,QD2015N006,GⅡ.4诺如病毒保守中和表位研究,2015/12-2017/11,20万元,结题,主持。
6. 广东省医学科研基金,B2010174,GII-4型诺如病毒P颗粒的表达与结构功能研究,2010/10-2011/10,1万元,已结题,主持。
7. 国家自然科学基金青年基金,30700716,GII-4型诺如病毒P颗粒的表达与结构功能研究,2008/01-2010/12,18万元,已结题,主持。
代表论文
1) Jia-Heng Li; Duona Jing; Yu Wang; Jiayi Xu; Junxuan Yu; Huisha Du; Qing Chen; Shixing Tang; Xu-Fu Zhang; Ying-Chun Dai(*) ; Establishment and application of a rapid assay for GII.4/GII.17 NoV detection based on the combination of CRISPR/Cas13a and isothermal amplification, Front. Microbiol., 2024, 15(2): 1334387
2) Jing-Rong Yu; Dong-Jie Xie; Jia-Heng Li; Mark Momoh Koroma; Lu Wang; Yu Wang; Duo-Na Jing; Duo-Na Jing; Jia-Yi Xu; Jun-Xuan Yu; Hui-Sha Du; Fei-Yuan Zhou; Zhi-Yan Liang; Xu-Fu Zhang; Ying-Chun Dai (*); Serological surveillance of GI norovirus reveals persistence of blockade antibody in a Jidong community-based prospective cohort, 2014-2018, Front Cell Infect Microbiol ., 2023, 18(13): 1258550
3) Liang Z, Zhang M, Wang Y, Koroma MM, Yu J, Zhou F, Jing D, Li J, Tang S, Chen Q and Dai Y-C(*) (2023). Development and evaluation of a new luciferase immunosorbent assay to detect GII.6 norovirus-specific IgG in different domestic and wild animals. Front. Microbiol. 14:1213007. doi: 10.3389/fmicb.2023.1213007
4) Bai, Y., Pu, C., Suo, Y., Zhang, X., Qu, Y., Feng, B., Huang, L., Shao, Y(*)., & Dai, Y(*). (2023). Exploring magnetic capture to improve the detection of human norovirus in strawberries. Food Frontiers, 1–12.
5) Mark Momoh Koroma (#), John Alimamy Kabba (#), Jessicah Wanda, Jingrong Yu, Feiyuan Zhou, Zhiyan Liang, Abu Bakarr Tarawally, Kuleza Chigoneka, Ying-Chun Dai (*). Under-five mortality in Sierra Leone and possible associated factors: evidence from the 2019 Demographic and Health Survey. Health Policy Plan. 2022 Nov 14;37(10):1210-1220.
6) Jingwei Shui1 (#), Dongjie Xie1 (#), Jianhui Zhao , Cailing Ao , Hongqing Lin, Yuanhao Liang , Haiying Wang , Yingchun Dai (*) and Shixing Tang (*). Seroepidemiology of Chlamydia trachomatis Infection in the General Population of Northern China: The Jidong Community Cohort Study. Frontiers in Microbiology, 2021, 12: 729016.
7) Lu Wang (#), Dongjie Xie (#), Jingrong Yu(#), Mark Momoh Koroma, Mengsi Qiu, Wentao Duan, Xu-Fu Zhang(*), Ying-Chun Dai(*). Serological surveillance of noroviruses in a community based prospective cohort: a study protocol. BMJ Open, 2021;April, 11:e043228.
8) Dongjie Xie(#), Junrui Chen (#) , Jingrong Yu , Fuyu Pei , Mark Momoh Koroma, Lu Wang , Mengsi Qiu , Yuzhen Hou, Dexian Yu , Xu-Fu Zhang (*), Ying-Chun Dai (*). Characterization of Antigenic Relatedness Among GI Norovirus Genotypes Using Serum Samples From Norovirus-Infected Patients and Mouse Sera.Front Microbiol, 2020 Dec 8;11:607723.
9) X. F. Zhang (#) , J. R. Chen(#), C. L. Song(#), D. J. Xie(#), M. Tan, L. Wang, M. M. Koroma, Y. Z. Hou, Z. P. Dong, J. R. Yu, W. T. Duan, D. D. Zhao, J. R. Du, L. Zhu and Y. C. Dai(*). Characterization of a hospital-based gastroenteritis outbreak caused by GII.6 norovirus in Jinshan, China. Epidemiology and Infection, 2020, Dec, 148, e289, 1–9.
10) Lun-Ai Guo(#), Meng Zhang(#), Yu-Zhen Hou (#) , Haitao Hu, Ling Fang , Ming Tan , Qiong Huang , Hui Li, Li-Mei Sun, Xi Jiang, Wen-Fang Tan , Shixing Tang , Xu-Fu Zhang(*), Ying-Chun Dai (*) , Epidemiology and HBGA-susceptibility investigation of a G9P[8] rotavirus outbreak in a school in Lechang, China, Arch Virol, 2020 Jun;165(6):1311-1320.
11) QIU Meng Si(#) ; WANG Xian Wei (#); YAO Yan; GE Si Qi; LIU Hua Min;
DAI Ying Chun(*) ; ZHOU Yong (*), Protocol of jidong Women Health Cohort Study: Rationale, Design, and Baseline Characteristics, Biomed Environ Sci, 2019, 32(2): 144-~152
12) Dai YC, Xia M, Huang Q, Tan M, Qin L, Zhuang YL, Long Y, Li JD, Jiang X, Zhang XF. Characterization of antigenic relatedness between GII.4 and GII.17 noroviruses using serum samples from norovirus-infected patients. J Clin Microbiol. 2017 Dec;55(12):3366-3373. doi: 10.1128/JCM.00865-17
13) Zhang, Xu-Fu ,Long, Yan ,Tan, Ming,Zhang, Ting,Huang, Qiong,Jiang, Xi,Tan, Wen-Fang,Li, Jian-Dong,Hu, Gui-Fang,Tang, Shixing,Dai, Ying-Chun*. P[8] and P[4] Rotavirus Infection Associated with Secretor Phenotypes Among Children in South China,Scientific Reports,2016.10.6,6:34591
14) Zhang, Xu-Fu ,Huang, Qiong ,Long, Yan,Jiang, Xi,Zhang, Ting,Tan, Ming,Zhang, Qiao-Li,Huang, Zhen-Yu,Li, Yue-Huan,Ding, Yao-Quan,Hu, Gui-Fang,Tang, Shixing,Dai, Ying-Chun*. An outbreak caused by GII.17 norovirus with a wide spectrum of HBGA-associated susceptibility.,Scientific Reports,2015.01.01,5:17687
15) Dai, Ying-Chun,Zhang, Xu-Fu,Xia, Ming,Tan, Ming,Quigley, Christina,Lei, Wen,Fang, Hao,Zhong, Weiming,Lee, Bonita,Pang, Xiaoli,Nie, Jun ,Jiang, Xi ,Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera,PLos One,2015.4.27,10(4):e0124945
16) Dai, Ying-Chun ,Zhang, Xu-Fu ,Tan, Ming,Huang, Pengwei,Lei,Wen,Fang, Hao,Zhong, Weiming,Jiang, Xi ,A dual chicken IgY against rotavirus and norovirus,Antiviral Research,2013.3.01,97(3):293~300
17) Dai, Ying-Chun,Wang, Yun-Yun,Zhang, Xu-Fu,Tan, Ming,Xia, Ming,Wu,Xian-Bo,Jiang, Xi ,Nie, Jun ,Evaluation of anti-norovirus IgY from egg yolk of chickens immunized with norovirus P particles,Journal of Virological Methods,2012.12.01,186(1-2):126~131
18) Dai, Ying-chun ,Hu, Gui-fang ,Zhang, Xu-fu,Song, Can-lei,Xiang, Wen-long,Wu, Xian-bo,Wang, Le-yi,Jiang, Xi ,Nie, Jun,Molecular epidemiology of norovirus gastroenteritis in children in Jiangmen, China, 2005-2007,Archives of Virology,2011.9.01,156(9):1641~1646
19) Dai, Ying-chun,Xu, Qiao-hua,Wu, Xian-bo,Hu, Gui-fang,Tang, Ya-li,Li, Jian-dong,Chen, Qing,Nie, Jun . Development of real-time and nested RT-PCR to detect astrovirus and one-year survey of astrovirus in Jiangmen City, China,Archives of Virology,2010.6.01,155(6):977~982
20) Dai, Ying-Chun,Xia, Ming,Zhan, Hui-Chun,Liu, Yi,Li, Jian-Dong,Chen, Qing,Yu, Shou-Yi,Nie, Jun ,Farkas, Tibor,Jiang, Xi. Surveillance and risk factors of norovirus gastroenteritis among children in a southern city of China in the fall-winter seasons of 2003-2006,Journal of Paediatrics and Child Health,2010.2.01,46(1-2):45~50
21) Dai, YC,Nie, J,Zhang, XF,Li, ZF,Yang, B,Zeng, ZR,Yu, SY,Farkas, T,Xi, J .Seroprevalence of antibodies against noroviruses among students in a Chinese military medical university,Journal of Clinical Microbiology,2004.1 0.01,42(10):4615~4619
22) Zhang, Xu-Fu,Tan, Ming ,Monica Chhabra,Meller Jarek, Dai, Ying-Chun, Jiang, Xi ,Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections,PLoS One,2013.01.01,8(7):e69379
23) Zhang, Xu-Fu,Dai, Ying-Chun,Zhong, Weiming,Tan, Ming,Lv, Zhi-Ping,Zhou, Ying-Chun ,Jiang, Xi ,Tannic acid inhibited norovirus binding to HBGA receptors, a study of 50 Chinese medicinal herbs,Bioorganic & Medicinal Chemistry,2012.2.15,20(4):1616~1623
专利
1) 白亚龙;周昌艳;张绪富;索玉娟;戴迎春;瞿洋;邵毅.一种检测果蔬中诺如病毒的方法.授 权 公 告 日:2023年10月03日, 授 权 公 告 号:CN 112080588 B
2)DAI, Ying-Chun,JIANG, Xi,IGY FROM NOROVIRUS P PARTICLES AND THEIR DERIVATIVES,2015.03.10,WIPO,PCT/US2013/050044