学术任职
中国营养学会特殊营养分会常务委员,广东微量元素学会理事
研究方向
膳食因素与慢性病
讲授课程
营养与食品卫生学、儿童少年卫生学
科研项目
1. 广东省自然科学基金面上项目,基于STAT3改善线粒体损伤和抑制铁死亡探讨丁酸钠抗炎症性肠病作用及其机制,2024.01-2026.01,15万元,主持
2. 广东省自然科学基金面上项目,基于CD44/SLC7A11通路探讨丁酸钠诱导结直肠癌细胞铁死亡作用及其机制(No.2022A1515011631),2022.01-2024.01,10万元,主持
3. 国家自然科学基金面上项目,基于线粒体-内质网交互作用和钙稳态失衡探讨丁酸钠抗结直肠癌作用及其机制(No.81773429),2018.01-2021.12,60万元,主持
4. 国家自然科学青年基金,钙池调控钙内流对丁酸钠诱导大肠癌细胞凋亡调控机制的研究(No.81202204),2013.01-2015.12,23万元,主持
5. 广东省自然科学基金面上项目,钙池调控钙内流对丁酸钠诱导大肠癌细胞凋亡调控机制的研究(No.2012010009467),2012.10-2014.10,5万元,主持
6. 南方医科大学优秀青年教师培育计划,内质网应激在丁酸钠诱导大肠癌细胞自噬中的作用及其机制研究(No.C1031691),2012.10-2014.10,5万元,主持
代表论文
1. Zhongbo Bian, Xiaodie Sun, Lulin Liu, Yong Qin, Qiuyu Zhang, Huahuan Liu, Lianzhi Mao, Suxia Sun*. Sodium Butyrate Induces CRC Cell Ferroptosis via the CD44/SLC7A11 Pathway and Exhibits a Synergistic Therapeutic Effect with Erastin. Cancers. 2023 Jan 9;15(2):423. (中科院2区,5.2)通讯作者
2. Zhongbo Bian, Qiuyu Zhang,Yong Qin, Xiaodie Sun, Lulin Liu, Huahuan Liu, Lianzhi Mao, Yiran Yan, Wenzhen Liao, Longying Zha, Suxia Sun*, Sodium butyrate inhibits oxidative stress and NF-κB/NLRP3 activation in dextran sulfate sodium salt-induced colitis in mice colitis with involvement of the Nrf2 signaling pathway and mitophagy. Digestive Diseases and Sciences. 2023, 68(7):2981-2996.(中科院4区,3.1)通讯作者
3. Ziyin Li, Lianzhi Mao, Bin Yu, Huahuan Liu, Qiuyu Zhang, Zhongbo Bian, Xudong Zhang, Wenzhen Liao*, Suxia Sun*. GB7 acetate, a galbulimima alkaloid from Galbulimima belgraveana, possess anticancer effects in colorectal cancer cells. Journal of Pharmaceutical Analysis. 2022, 12(2), 339-349.(中科院1区,8.8)通讯作者
4. Huahuan Liu, Zhongbo Bian, Qiuyu Zhang, Zhipeng Xiao, Yu Cao, Xiaodie Sun, Yong Qin, Lianzhi Mao, Xinwei Chu, Wenzhen Liao, Longying Zha, Suxia Sun*. Sodium butyrate inhibits colitis-associated colorectal cancer through preventing the gut microbiota dysbiosis and reducing the expression of NLRP3 and IL-1β. Journal of Functional Foods. 2021 Dec 20; doi:org/10.1016/j.jff.2021.104862. (中科院2区,5.6) 通讯作者
5. Lianzhi Mao, Huahuan Liu, Rongjun Zhang, Yudi Deng, Yuting Hao, Wenzhen Liao*, Miaomiao Yuan*, Suxia Sun*. PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells,Aging (Albany NY). 2021 Apr 30;13(9):12955-12972. doi: 10.18632/aging.202965. (中科院3区,5.2)通讯作者
6. Alessandra Cavaliere, Suxia Sun, Supum Lee, Jacob Bodner, Ziqi Li,Yiyun Huang, Sheri L. Moores, Bernadette Marquez-Nostra. Development of [89Zr]ZrDFO-amivantamab bispecific to EGFR and c-MET for PET imaging of triple-negative breast cancer. Eur J Nucl Med Mol Imaging. 2021 Feb;48(2):383-394. (中科院1区,9.1) 排名第二
7. Shunli Luo, Ziyin Li, Lianzhi Mao, Siqiang Chen, Suxia Sun*. Sodium butyrate induces autophagy in colorectal cancer cells through LKB1/AMPK signaling. Journal of Physiology and Biochemistry. 2019 Feb;75(1):53-63.(中科院3区,3.4) 通讯作者
8. Liao W, Liu Z, Zhang T, Sun S, Ye J, Li Z, Mao L, Ren J. Enhancement of Anti-Inflammatory Properties of Nobiletin in Macrophages by a Nano-Emulsion Preparation. J Agric Food Chem. 2018 Jan 10;66(1):91-98. doi: 10.1021/acs.jafc.7b03953. (中科院1区,6.1)
9. Lixia Yang, Shilei Pan, Yufeng Zhou, Xiaoyang Wang, Aikai Qin, Yuxin Huang, Suxia Sun*. The correlation between serum vitamin D deficiency and preterm birth[J]. Med Sci Monit. 2016 Nov 16;22:4401-4405. doi: 10.12659/msm.898117. (中科院3区,3.1),通讯作者
10. Jintao Zhang, Man Yi, Longying Zha, Siqiang Chen, Zhijia Li, Cheng Li, Mingxing Gong, Hong Deng, Xinwei Chu, Jiehua Chen, Zheqing Zhang, Limei Mao, Suxia Sun*. Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for apoptosis. PLoS One. 2016 Jan 19;11(1):e0147218.(中科院3区,3.7) 通讯作者
11. Chen J, Sun S, Zha D, Wu J, Mao L, Deng H, Chu X, Luo H, Zha L. Soyasaponins Prevent H2O2-Induced Inhibition of Gap Junctional Intercellular Communication by Scavenging Reactive Oxygen Species in Rat Liver Cells. Nutr Cancer. 2014;66(8):1342-51.(中科院4区,2.9),共同第一
12. Zha L, Chen J, Sun S, Mao L, Chu X, Deng H, Cai J, Li X, Liu Z, Cao W. Soyasaponins can blunt inflammation by inhibiting the reactive oxygen species-mediated activation of PI3K/Akt/NF-kB pathway. PLoS One. 2014 Sep 18;9(9):e107655. (中科院3区,3.7)
13. Suxia Sun, Wenjun Li, He Zhang, Longying Zha, Yong Xue, Xianbo Wu, and Fei Zou. Requirement for store-operated calcium entry in sodium butyrate-induced apoptosis in human colon cancer cells. Bioscience reports. 2012; 32(1): 83-90. (中科院3区,4.0),第一作者
14. He Zhang, Wenjun Li, Suxia Sun, Shaozhen Yu, Minhong Zhang and Fei Zou. Inhibition of sphingosine kinase 1 suppresses the growth of glioma cells under hypoxia by attenuating the activity of extracellular signal-regulated5 kinase. Cell Proliferation. 2012; 45(2): 167-75. (中科院1区,8.5),共同第一作者
15. 孙小蝶,秦勇,刘璐琳,张秋玉,卞中博,孙素霞*. 丁酸钠通过诱导铁死亡抑制肝癌细胞增殖. 营养学报, 2023, 45(2): 157-162. 通讯作者
16. 秦勇,孙小蝶,刘璐琳,卞中博,张秋玉,孙素霞*. 线粒体钙离子单向转运蛋白对丁酸钠抗结直肠癌的作用及机制. 中华肿瘤防治杂志, 2022, 29(20): 1467-1474. 通讯作者
17. 张秋玉, 卞中博, 孙小蝶, 秦勇, 刘华缓, 毛联智, 孙素霞*. 丁酸钠通过自噬降解HIF-1α抑制结直肠癌细胞生长. 现代肿瘤医学. 2022, 30(5): 762-767. 通讯作者
18. 卞中博, 张秋玉, 秦勇, 孙小蝶, 刘华缓, 毛联智, 孙素霞*. 丁酸钠对DSS诱导小鼠炎症性肠病的作用及对Nrf 2/NFκB表达影响. 营养学报. 2022, 44(1): 72-78. 通讯作者
19. 刘华缓,曹誉,肖志鹏,毛联智,孙素霞*. 丁酸钠对AOM/DSS炎症相关性结直肠癌小鼠模型及其肠道菌群的影响. 中华肿瘤防治杂志, 2021, 28(18): 1368-1377. 通讯作者
20. 毛联智, 刘会平, 刘华缓, 卞中博, 张秋玉, 廖文镇, 孙素霞*. 攀登鱼藤异黄酮脂质体有较好的物理性能及抗乳腺癌细胞的增殖活性. 南方医科大学学报, 2020, 40(6): 876-883. 通讯作者
21. 罗顺莉,黎姿茵,毛联智,李楠,谢雨蓓,孙素霞*. 丁酸钠通过Ca2+-CaMKKβ信号通路诱导结直肠细胞自噬. 营养学报,2018.40(2):142-147. 通讯作者
22. 谢文权,陈嘉定,李程,陈晓洋,张锦涛,伊曼,孙素霞*. 丁酸钠诱导大肠癌HCT-116细胞自噬的研究. 中华肿瘤防治杂志, 2015; 22(5):340-343. 通讯作者
23. 孙素霞,李文军,陈思强,罗海吉,邹飞. 丁酸钠对大肠癌HT-29细胞凋亡以及钙离子浓度的影响. 营养学报,2013. 35(1):27-34. 第一作者