姓名:王慧君
电子邮箱:hjwang@smu.edu.cn
工作单位:南方医科大学法医学院
技术职称:二级教授,主任法医师
学术任职:广东省司法鉴定协会会长,中国教育部法医学专业教学指导委员会委员,司法部司法鉴定高级专业技术职务任职资格评审委员会委员,公安部法医病理重点实验室特聘专家,广东省人大常委会聘任立法咨询专家,广州市白云区人民检察院专家咨询组委员,广东省医疗事故处理委员会特聘专家, 《Forensic Sciences Research》编委,《Journal of Forensic Science and Medicine》编委,司法部《法医学杂志》编委,南方医科大学学报编辑部编委等。
研究领域(方向):毒品的毒性损伤机制研究,心源性猝死的法医学研究,法医病理学死亡时间的推断和损伤时间推断。
个人简历:
留德博士,二级教授,主任法医师,博士生导师,现任南方医科大学法医学院首席科学家,广东省司法鉴定协会会长。
从零起步,牵头建立和建设了南方医科大学法医学学科,完成了从教研室到法医学系再到法医学院的建立和建设,完成了我校从法医学专业本科生招生,硕士、博士点建立、招生,到博士后联合培养基地完整的法医学教育体系建设,为我国输送高层次法医人才。近年来共获科研基金二十余项,主持16项,含国家自然科学基金7项(其中重点项目1项),科研经费共计约750多万元。发表研究论文百余篇,其中SCI论文28篇,最高影响因子34.833(《新英格兰医学杂志》),出版专著10部。
牵头建立和建设的南方医科大学司法鉴定中心、交通事故司法鉴定技术研究所,面向社会提供高科技司法鉴定服务,每年承接万余例案件和事件的鉴定,产生了巨大的社会效益和经济效益,较好地发挥了高等院校科技力量服务社会的职能,在技生产力转化为经济效益和社会效益中发挥了重要作用。
曾获中华医学科技奖一等奖一项(排名第四),军队科技进步二等奖一项(排名第二),获中国人民解放军总后勤部育才奖银,荣立三等功一次。获司法部 “法律服务主题实践活动”先进个人、广东省精神文明建设先进个人、广州市抗击非典先进个人、南粤优秀教师、南医优秀教师、南医十佳导师等称号。
科研:
1.2005年获中华医学科技奖一等奖一项(排名第四)(国家级)
2.2004年获得军队科技进步二等奖(排名第二)一项(部级)
3.2004年被广州市(市级)评为防“非典”先进个人(获金质奖章)
4.2004年荣立中国人民解放军总后勤部三等功一次(部级)
5.2003年荣获中国人民解放军总后勤部育才奖银奖(部级)
教学:
1.2018年获南粤优秀教师称号
2.2017年获南方医科大学优秀教师
3.2017年获南方医科大学十佳导师
4.2016年获南方医科大学2015-2016年度教学优秀一等奖
社会服务:
1.2005年被评为广东省精神文明先进个人(省级)
2.2009年被司法部评为“法律服务主题实践活动”先进个人(国家级)
近五年发表论文:
2022年:
1. Cui Zhang , Chuanxiang Chen, Xu Zhao, Jiancong Lu, Manting Zhang, Hai Qiu, Xia Yue,*, Huijun Wang,* New insight into methamphetamine-associated heart failure revealed by transcriptomic analyses: Circadian rhythm disorder,Toxicology and Applied Pharmacology 451 (2022) 11617,22022 Jul 1
2. Yukun Du,Jingjian Liu,Qi Li,Huan Li,Xiaodong Kang,Dongyun Zheng, He Shi,Quyi Xu,Chao Liu*,Huijun Wang*,Jian Zhao*,Concordance analysis of diatom types and patterns in lung tissue and drowning medium in laboratory animal model,International Journal of Legal Medicine,2022 May;136(3):911-917.
3. Chuanxiang Chen#,Cui Zhang#,Yongjian Deng,Sihao Du, Huijun Wang*, Dongri Li*,Thymic hypoplasia induced by copy number variations contributed to explaining sudden infant death based on forensic autopsies,Forensic Science International 336 (2022) 111323
2021年:
4. Xu Zhao ,Jiancong Lu,Xuebing Chen ,Zhengxiang Gao,Cui Zhang,Chuanxiang Chen ,Dongfang Qiao*,Huijun Wang*,Methamphetamine exposure induces neuronal programmed necrosis by activating the receptor‐interacting protein kinase 3-related signalling pathway,FASEB J. 2021 May;35(5):e21561.
5. Zhonghao Yu, Quyi Xu, Cheng Xiao, Huan Li, Weibin Wu, Weian Du, Jian Zhao,
Hong Liu, Huijun Wang*, Chao Liu*,SYBR Green real-time qPCR method: Diagnose drowning more rapidly and accurately,Forensic Science International 321 (2021) 110720.
6. Chao Zhang, RongFang Ding, YiCheng Sun, Si Tong Huo, Alina He, Chang Wen,HongHao Chen, William W. Du, WeiNan Lai, Huijun Wang*,Circular RNA in tumor metastasis, Molecular Therapy: Nucleic Acids Vol. 23 March 2021
7. Dong Qu, Na Chen, Dong-Fang Qiao, Hui-Jun Wang*, Xiao-Hui Tan*,Rarely fatal bilateral re-expansion pulmonary edema after inserting a chest tube for unilateral spontaneous pneumothorax: a case report, Forensic Sci Med Pathol. 2021 Mar;17(1):114-119.
2020年:
1. Xiao-Hui Tan, Kai-Kai Zhang, Jing-Tao Xu, Dong Qu, Li-Jian Chen, Jia-Hao Li, Qi Wang*, Hui-Jun Wang*, Xiao-Li Xie*,Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats, Food and Chemical Toxicology, 2020 Mar;137:111179.
2. Xuebing Chen,Feng Qiu,Xu Zhao,Jiancong Lu,Xiaohui Tan,Jingtao Xu,Chuanxiang Chen,Fu Zhang,Chao Liu,Dongfang Qiao*,Huijun Wang*,Astrocyte-Derived Lipocalin-2 Is Involved in Mitochondrion-Related Neuronal Apoptosis Induced by Methamphetamine,ACS Chem Neurosci. 2020 Apr 15;11(8):1102-1116. doi: 10.1021/acschemneuro.9b00559. Epub 2020 Mar 27.
3. 王慧君#,从SARS-CoV到SARS-CoV-2:法医传染病尸体检验的应对与挑战,法医学杂志,2020.36 (1): 1-3.
4. 王慧君#,杜思昊,岳霞,陈传香,冠状病毒肺炎的病理学特征回顾与展望,法医学杂志,2020.36 (1): 16-20.
5. 邱海, 王慧君, 陈倩玲,岳霞,新型冠状病毒疫情期法医学尸体检验的安全防护,法医学杂志,2020.36 (1): 24-28.
6. Dong Qu, Kaikai Zhang, Lijian Chen, Qi Wang and Huijun Wang*,RNA-sequencing analysis of the effect of luteolin on methamphetamine-induced
hepatotoxicity in rats: a preliminary study PeerJ. 2020 Feb 6;8:e8529. doi: 10.7717/peerj.8529. eCollection 2020,peerj 8.e8529.
7. Yiyu Chen, Zhen Liu, Huijun Wang, Zibo Tang, Yiyi Liu, Zixi Liang, Xiaojie Deng, Mengyang Zhao, Qiaofen Fu, Libo Li, Hongbing Cai, Weibing Xie and Weiyi Fang,VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer, Int J Cancer. 2020 Jan 15;146(2):496-509.
2019年:
1. Chen X, Lu J, Zhao X, Chen C, Qiao D, Wang H*, Yue X*. Role of c/ebp-beta in methamphetamine-mediated microglial apoptosis. Front Cell Neurosci. 2019 Aug 21;13:366.
2. Dong Qu, Xiao Hui Tan, Kai-kai Zhang, Qi Wang*, Hui Jun Wang*,ATF3 mRNA, but not BTG2, as a possible marker for vital reaction of skin contusion, Forensic Sci Int. 2019 Sep 12;303:109937.
3. Xiang Xu, Enping Huang, Baoying Luo#, Dunpeng Cai, Xu Zhao, Qin Luo, Yili Jin, Ling Chen, Qi Wang, Chao Liu, Zhoumeng Lin, Wei-Bing Xie*, and Huijun Wang* ,Methamphetamine exposure triggers apoptosis and autophagy in neuronal cells by activating the C/EBPb-related signaling pathway,FASEB J. 2018.32(12):6737-6759.
2018年:
1. Du SH, Zhang W, Yue X, Luo XQ, Tan XH, Liu C, Qiao DF*, Wang H*. Role of CXCR1 and Interleukin-8 in Methamphetamine-Induced Neuronal Apoptosis.Front Cell Neurosci. 2018 Aug 3;12:230.
2. Wei Qi Hao,Jing Liu,Li Jiang,Jun Ping Han,Ling Wang,Jiu Ling Li,Quan Ma,Chao Liu*,Hui Jun Wang*,Cai-Xia Li*,Exploring the ancestry differentiation and inference capacity of the 28-plex AISNPs, Int J Legal Med. 2019 ;133(4):975-982.
3. Ning X, Fu Z, Zhu B, Chao L, Lin Z, Wang H*, Xie Weibing*. Cdk5-mediated tau accumulation triggers methamphetamine-induced neuronal apoptosis via endoplasmic reticulum-associated degradation pathway. Toxicol Lett.2018 Aug;292:97-107.
4. Lizeng Li, Si Chen, Yue Wang,Xia Yue,Jingtao Xu,Weibing Xie,Pingming Qiu,Chao Liu,AiFeng Wang*and Huijun Wang*,Role of GSK3β/α-synuclein axis in methamphetamine-induced neurotoxicity in PC12 cells, Toxicol Res,2018.7: 22;7(2):221-234.
2017年:
1. Si Hao Du, Dong Fang Qiao, Chuan Xiang Chen, Si Chen, Chao Liu, Zhoumeng Lin, Huijun Wang*, Weibing Xie*,Toll-like receptor 4 mediates methamphetamine-induced neuroinflammation through Caspase-11 signaling pathway in astrocytes. Front Mol Neurosci. 2017 Dec 12;10:409..
2. Xiang Xu, Enping Huang, Yunchun Tai, Xu Zhao, Xuebing Chen, Chuanxiang Chen, Rui Chen, Chao Liu, Zhoumeng Lin, Huijun Wang*, Weibing Xie*. Nupr1 modulates methamphetamine-induced dopaminergic neuronal apoptosis and autophagy through CHOP-Trib3-mediated endoplasmic reticulum stress signaling pathway. Front Mol Neurosci. 2017 Jun 26;10:203.
3. Li B, Chen R, Chen L, Qiu P, Ai X, Huang E, Huang W, Chen C, Liu C, Lin Z, Xie WB*, Wang H*. Effects of DDIT4 in Methamphetamine-Induced Autophagy and Apoptosis in Dopaminergic Neurons. Mol Neurobiol. 2017 Apr;54(3):1642-1660.