博后工作

一、基本信息

姓名：查龙应

职称：教授

联系邮箱：lyzha@smu.edu.cn

二、学习经历

1997.9-2001.7 安徽农业大学，动物科学专业，学士

2001.9-2004.7 贵州大学，动物遗传与育种专业，硕士

2004.9-2007.7 浙江大学，动物营养与饲料科学专业，博士

2013.3-2015.3 美国北卡罗来纳大学教堂山分校（UNC-Chapel Hill），营养学专业，访问学者/博士后

三、拟招收博士后开展的研究方向

1. 食物中生物活性成分与慢性非传染性疾病防治；

2. 代谢性炎症分子机制及其膳食营养防治。

四、主要学术任职

1. 中国营养学会，理事

2. 广东医学微量元素学会，理事长

3. 广东省营养学会，副理事长

4. 美国营养学会，会员

5. 北美华人营养学会，会员

6. 中国营养学会营养与保健食品分会，委员

7. 中国营养学会营养与组学技术分会，委员

8. 中国生物化学与分子生物学学会，会员

9. 广东省保健协会体重管理分会，副主任委员

10. 广东省营养学会青年工作委员会，副主任委员

11. 广东省营养学会营养与慢病管理专业委员会，常务委员

12. 中华预防医学会自由基专业委员会，委员

13. 广州市国家慢性病综合防控示范区专家组成员

五、主要获奖情况

1. 2012, 广东省高等学校千百十工程培养对象（第七批）

2. 2016, 广东省第一届中青年教师公共卫生与预防医学本科课程教学竞赛一等奖

3. 2019, 南医优秀教师（第十届）

4. 2021, 指导学生获得第十届中国大学生医学技术技能大赛预防医学专业赛道华中华南分区赛一等奖

5. 2022, 指导学生获得第十届中国大学生医学技术技能大赛预防医学专业赛道总决赛银奖

六、代表性论文

1. Fengjuan Lin^#, Huiyu Luo^#, Jiexian Wang, Qing Li, Longying Zha*. Macrophage-derived extracellular vesicles as new players in chronic non-communicable diseases. Frontiers in Immunology, 2025, 15:1479330. (SCI收录，JCR1区，中科院小类2区，五年IF=6.8)

2. Jiexian Wang, Yanhua Wu, Junyi Yang, Shihao Ying, Huiyu Luo, Longying Zha*, Qing Li*. Xylooligosaccharide and Akkermansia muciniphila synergistically ameliorate insulin resistance by reshaping gut microbiota, improving intestinal barrier and regulating NKG2D/NKG2DL signaling in gestational diabetes mellitus mice. Food Research International, 2025, 201: 115634. (SCI收录，JCR1区，中科院小类1区，五年IF=7.4)

3. Huiyu Luo, Jiexian Wang, Fengjuan Lin, Yuguo Liu, Xinglong Wu, Gan Li, Chuhong Su, Junbin Chen, Fei Xiong, Jiaqi Mo, Zhongdaixi Zheng, Xiangyi Zheng, Qing Li, Longying Zha*. Macrophage exosomes mediate palmitic acid-induced metainflammation by transferring miR-3064-5p to target IκBα and activate NF-κB signaling. Journal of Advanced Research, 2024, S2090-1232(24)00261-3. (SCI收录，JCR1区，中科院小类1区，五年IF=11.0)

4. Chuhong Su, Jiexian Wang, Huiyu Luo, Junbin Chen, Fengjuan Lin, Jiaqi Mo, Fei Xiong, Longying Zha*. Gut microbiota plays essential roles in soyasaponin’s preventive bioactivities against steatohepatitis in the methionine and choline deficient (MCD) diet-induced nonalcoholic steatohepatitis (NASH) mice. Molecular Nutrition and Food Research. 2024, 68(4): e2300561. (SCI收录，JCR1区，中科院小类2区，五年IF=5.6)

5. Zhongdaixi Zheng, Jiaqi Mo, Fengjuan Lin, Jiexian Wang, Junbin Chen, Huiyu Luo, Yuguo Liu, Chuhong Su, Xiangfu Gu, Fei Xiong, and Longying Zha*. Milk exosomes from gestational diabetes mellitus (GDM) and healthy parturient exhibit differential miRNAs profiles and distinct regulatory bioactivity on hepatocyte proliferation. Molecular Nutrition and Food Research. 2023, 67(16): e2300005. (SCI收录，JCR1区，中科院小类2区，五年IF=5.6)

6. Huiyu Luo, Junbin Chen, Chuhong Su, Longying Zha*. Advances in the Bioactivities of Phytochemical Saponins in the Prevention and Treatment of Atherosclerosis. Nutrients, 2022, 14(23): 4998. (SCI收录，JCR1区，中科院小类2区，五年IF=5.8)

7. Junbin Chen, Yuguo Liu, Huiyu Luo, Guoxun Chen, Zhongdaixi Zheng, Tiannan Wang, Xinge Hu, Yue Zhao, Jiaqi Tang, Chuhong Su and Longying Zha*. Inflammation Induced by Lipopolysaccharide and Palmitic Acid Increases Cholesterol Accumulation via Enhancing Myeloid Differentiation Factor 88 Expression in HepG2 Cells. Pharmaceuticals, 2022, 15(7): 813. (SCI收录，JCR1区，中科院小类2区，五年IF=4.6)

8. Xiangfu Gu^#, Jiaqi Tang^#, Yue Zhao^#, Chuhong Su, Lingyu Xiao, Huiyu Luo, Yuguo Liu, Fei Xiong, Zhongdaixi Zheng, Junbin Chen, Longying Zha*. Soyasaponin A₁ inhibits the lipid raft recruitment and dimerization of TLR4, MyD88, and TRIF by maintaining cholesterol homeostasis in palmitic acid-stimulated inflammatory Raw264.7 macrophage cell line. Journal of Functional Foods, 2021, 87: 104789. (SCI收录，JCR2区，中科院小类3区，五年IF=4.6)

9. Fei Xiong^#, Zhongdaixi Zheng^#, Lingyu Xiao^#, Chuhong Su, Junbin Chen, Xiangfu Gu, Jiaqi Tang, Yue Zhao, Huiyu Luo, Longying Zha*. Soyasaponin A₂ Alleviates Steatohepatitis Possibly through Regulating Bile Acids and Gut Microbiota in the Methionine and Choline Deficient (MCD) Diet-induced Non-alcoholic Steatohepatitis (NASH) Mice. Molecular Nutrition and Food Research, 2021, 65(14): e2100067. (SCI收录，JCR1区，中科院小类2区，五年IF=5.6)

10. Qunying Xie^#, Fei Xiong^#, Xinglong Wu^#, Junbin Chen, Xiangfu Gu, Chuhong Su, Lingyu Xiao, Zhongdaixi Zheng, Yuanhao Wei, Ullah Hydayat, Longying Zha*. Soyasaponin A₁ and A₂ exert anti-atherosclerotic functionality by decreasing hypercholesterolemia and inflammation in high fat diet (HFD)-fed apoE^-/- mice. Food and Function, 2020, 11: 253.(SCI收录，JCR1区，中科院小类2区，五年IF=5.6)