研究方向
1. 职业性肿瘤的免疫逃逸机制
2. 乳腺癌转移及嗜器官机制
讲授课程
职业卫生与职业医学 卫生学 卫生信息管理
科研项目
国家自然科学基金面上项目,32171408,基于MCU负性介导miR4488的分选对CFES体系的改良和研究,2022-01-01至2025-12-31,58万元,在研,主持
代表论文
(1) Zheng, Xianchong; Chen, Mimi; Meng, Xiaojing; Chu, Xinwei; Cai, Chunqing; Zou, Fei ; Phosphorylation of dynamin-related protein 1 at Ser616 regulates mitochondrial fission and is involved in mitochondrial calcium uniporter-mediated neutrophil polarization and chemotaxis, MOLECULAR IMMUNOLOGY, 2017, 87: 23-32
(2) Zhang, Siheng; Miao, Yutian; Zheng, Xianchong; Gong, Yong; Zhang, Jinxin; Zou, Fei; Cai, Chunqing ; STIM1 and STIM2 differently regulate endogenous Ca2+ entry and promote TGF-beta-induced EMT in breast cancer cells, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 488(1): 74-80 (3) Hehai Huang; Xianchong Zheng; Changqing Cai; Zhuocheng Yao; Sitong Lu; Xiaojing Meng; Yutian Miao; Zhanxin He; Chunqing Cai; Fei Zou ; Exosomes derived from breast cancer lung metastasis subpopulations promote tumor self-seeding, Biochemical and Biophysical Research Communications, 2018, 503: 242-248
(4) Xianchong Zheng; Sitong Lu; Zhanxin He; Hehai Huang; Zhuocheng Yao; Yutian Miao; Chunqing Cai; Fei Zou ; MCU-dependent negative sorting of miR-4488 to extracellular vesicles enhances angiogenesis and promotes breast cancer metastatic colonization, Oncogene, 2020, 39(46): 6975-6989
(5) Yutian Miao; Qiang Shen; Siheng Zhang; Hehai Huang; Xiaojing Meng; Xianchong Zheng; Zhuocheng Yao; Zhanxin He; Sitong Lu; Chunqing Cai; Fei Zou ; Calcium-sensing stromal interaction molecule 2 upregulates nuclear factor of activated T cells 1 and transforming growth factor-β signaling to promote breast cancer metastasis, breast cancer research, 2019, 21(1): 99