一、基本信息
姓名：莫志贤
职称：教授
联系邮箱：1021336808@qq.com
二、学习经历
1978.2-1982.12 广西医科大学，临床医学专业，学士
1985.8-1988.7 第三军医大学，药理学专业，硕士
三、拟招收博士后开展的研究方向
1. 中药神经精神药理学；
2. 中药抗肿瘤药理学；
3. 中药新药的创制及临床前研究；
4. 中药健康产品的研究与开发。
四、主要学术任职
1. 国家科学技术奖评审专家；
2. 中华医学科技奖评审委员会委员；
3. 广东省药理学会中药药理专业委员会，常务委员；
4. 广东省药品审评认证中心药品注册审评专家；
5. 广东省药品不良反应监测中心专家；
6. 《南方医科大学学报》特约编委。
五、主要获奖情况
科学技术二等奖，中华中医药学会，2011
六、代表性论文
1. Miranda F.K.Suena, W.S.Chan, KarenW.Y.Hung, Y.F.Chen, Z.X.Mo, Ken K.L.Yung, Assessments of the effects of nicotine and ketamine using tyrosine hydroxylase-green fluorescent protein transgenic zebrafish as biosensors, Biosensors and Bioelectronics，2013，42：177–185
2. Chan Li, Genghong Tu, Chaohua Luo, Youli Guo, Miao Fang, Chen Zhu, Hancheng Li, Jinying Ou, Yuting Zhou, Wei Liu, Ken Kin Lam Yung, Zhixian Mo. Effects of rhynchophy- lline on the hippocampal miRNA expression profile in ketamine-addicted rats. Progress in Neuropsychopharmacology & Biological Psychiatry. 2018, 86：379–389
3. Mingjin Jiang, Jing Li, Qiuxian Peng, Yi Liu, Wei Liu, Chaohua Luo, Ju Peng, Junkui Li, Ken Kin Lam Yung, Zhixian Mo, Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation, Journal of Neuroinflammation, 2014, 11:167
4. Mingjin Jiang#, Yifei Chen#, Chan Li, Qiuxian Peng, Miao Fang, Wei Liu, Qunzhao Kang, Yingbo Lin, Ken Kin Lam Yung, Zhixian Mo. Inhibiting effects of rhynchophylline on zebrafish methamphetamine dependence are associated with amelioration of neurotransmitters content and down-regulation of TH and NR2B expression. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2016, 68: 31-43
5. Karen W.Y. Hung, Miranda F.K. Suen, Y.F. Chen, H.B. Cai, Z.X. Mo, K.K.L. Yung. Detection of water toxicity using cytochrome P450 transgenic zebrafish as live biosensor: For polychlorinated biphenyls toxicity. Biosensors and Bioelectronics, 2012, 31（1）：548–553
6. Miao Fang , Daoqi Zhu, Chaohua Luo, Chan Li, Chen Zhu, Jinying Ou, Hancheng Li, Yuting Zhou, Chuying Huo, Wei Liu, Jiangli Peng, Qiuxian Peng, Zhixian Mo. In vitro and in vivo anti-malignant melanoma activity of Alocasia cucullata via modulation of the phosphatase and tensin homolog/phosphoinositide 3-kinase/AKT pathway. Journal of Ethnopharmacology, 2018,213: 359–365
7. Qiuxian Peng, Hongbing Cai, Xuegang Sun, Xin Li, Zhixian Mo, Jue Shi, Alocasia cucullata Exhibits Strong Antitumor Effect In Vivo by Activating Antitumor Immunity, PLOS ONE, 2013, 8( 9): e75328
8. Chen Zhu, Wei Liu, Chaohua Luo,Yi Liu,Chan Li, Miao Fang, Yingbo Lin, Jinying Ou, Minting Chen, Daoqi Zhu, Ken Kin-Lam Yung, Zhixian Mo. Inhibiting effects of rhynchophylline on methamphetamine-dependent zebrafish are related with the expression of tyrosine hydroxylase (TH), Fitoterapia, 2017, 117:47-51
9. Jinying Ou, Yuting Zhou, Chan Li, Zhijie Chen, Hancheng Li, Miao Fang, Chen Zhu, Chuying Huo, Ken Kin-Lam Yung, Jing Li, Chaohua Luo and Zhixian Mo. Sinomenine Protects Against Morphine Dependence through the NMDAR1/CAMKII/CREB Pathway: A Possible Role of Astrocyte-Derived Exosomes. Molecules, 2018, 23: 2370
10. Jun-Shan Liu1, Chu-Ying Huo1, Hui-Hui Cao, Chun-Lin Fan, Jian-Yang Hu, Li-Juan Deng, Zi-Bin Lu, Hua-Yi Yang, Lin-Zhong Yu, Zhi-Xian Mo, Zhi-Ling Yu. Aloperine induces apoptosis and G2/M cell cycle arrest in hepatocellular carcinoma cells through the PI3K/Akt signaling pathway. Phytomedicine, 2019, 61:152843
