窗体顶端
一、基本信息
姓名：徐江平
职称：教授
联系邮箱：jpx@smu.edu.cn
二、学习经历
1985.9-1990.7 第一军医大学，军医系, 学士
1990.9-1993.7 军事医学科学院毒物药物研究所, 药理学，硕士
1993.9-1997.7 军事医学科学院毒物药物研究所，药理学，博士
1997.8-1999.9 第二军医大学药学院，药学，博士后
三、拟招收博士后开展的研究方向
1、基础神经精神药理学；
2、新药临床前评价
四、主要学术任职
1. 中国药理学会神经精神药理学专业委员会，委员；
2. 中国药理学会教学与科普专业委员会，委员；
3. 广东省药理学会常务理事，神经药理学专业委员会，副主任委员；
4. 广东省药理学会药物毒理学专业委员会，副主任委员；
5. 国家食品药品监督管理局，新药审评专家；
6. 国家食品药品监督管理局，保健食品审评专家；
五、主要获奖情况
1. 广东省科学技术奖励，三等奖，广东省科技厅，2011；
2. 广东省优秀教学成果奖（精品课程），广东省教育厅，2007；
3. 广东省高等学校“千百十工程”国家级培养对象，广东省教育厅，2013
六、代表性论文
1. Zhang C, Cheng Y, Wang H, Wang C, Xu J*, Zhang H. RNA Interference-Mediated Knockdown of Long-Form Phosphodiesterase-4D (PDE4D) Enzyme Reverses Amyloid-β42-Induced Memory Deficits in Mice. J Alzheimers Dis. J Alzheimers Dis. 2014, 38(2):269-80.
2. Wang G, Cheng Y, Gong M, Liang B, Zhang M, Chen Y, Zhang C, Yuan X, Xu J*. Systematic correlation between spine plasticity and the anxiety/depression like phenotype induced by corticosterone in mice. Neuroreport. 2013;24(12):682-7.
3. Zhang MZ, Zhou ZZ, Yuan X, Cheng YF, Bi BT, Gong MF, Chen YP, Xu JP*. Chlorbipram: A novel PDE4 inhibitor with improved safety as a potential antidepressant and cognitive enhancer. European Journal of Pharmacology, 2013, 721(1-3):56-63.
4. Zhuo RG, Ma XY, Zhou PL, Liu XY, Zhang K, Wei XL, Yan HT, Xu JP, Zheng JQ*. Mas-related G protein-coupled receptor D is coupled to endogenous calcium-activated chloride channel in Xenopus oocytes. J Physiol Biochem. 2013 Sep 28. [Epub ahead of print]
5. Qiu ZK, Zhang LM, Zhao N, Chen HX, Zhang YZ, Liu YQ, Mi TY, Zhou WW, Li Y, Yang RF, Xu JP*, Li YF*. Repeated administration of AC-5216, a ligand for the 18 kDa translocator protein, improves behavioral deficits in a mouse model of post-traumatic stress disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2013；1(45):40-6.
6. Bi BT, Lin HB, Cheng YF, Zhou H, Lin T, Zhang MZ, Li TJ, Xu JP*. Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer's disease. Neurochem Int. 2012 ;60(3):257-66.
7. Jin ZL, Gao N, Zhou D, Chi MG, Yang XM, Xu JP*. The extracts of Fructus Akebiae, a preparation containing 90% of the active ingredient hederagenin: serotonin, norepinephrine and dopamine reuptake inhibitor. Pharmacol Biochem Behav. 2012 ;100(3):431-9.
8. Wang C, Yang XM, Zhuo YY, Zhou H, Lin HB, Cheng YF, Xu JP*, Zhang HT. The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats. Int J Neuropsychopharmacol. 2012 Jul;15(6):749-66.
9. Bin J, Wang Q, Zhuo YY, Xu JP*, Zhang HT. Piperphentonamine (PPTA) attenuated cerebral ischemia-induced memory deficits via neuroprotection associated with anti-apoptotic activity. Metab Brain Dis. 2012 Dec;27(4):495-505.
10. Yang X, Li G, Chen L, Zhang C, Wan X, Xu J*. Quantitative determination of hederagenin in rat plasma and cerebrospinal fluid by ultra fast liquid chromatography-tandem mass spectrometry method. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879(21):1973-9.
11. Li LX, Cheng YF, Lin HB, Wang C, Xu JP*, Zhang HT*. Prevention of cerebral ischemia-induced memory deficits by inhibition of phosphodiesterase-4 in rats. Metab Brain Dis. 2011;26(1):37-47.
12. Cheng YF, Wang C, Lin HB, Li YF, Huang Y, Xu JP*, Zhang HT*. Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats. Psychopharmacology (Berl). 2010;212(2):181-91.
13. Zhou D, Jin H, Lin HB, Yang XM, Cheng YF, Deng FJ, Xu JP*. Antidepressant effect of the extracts from Fructus Akebiae. Pharmacol Biochem Behav. 2010 Jan;94(3):488-95.
14. Li R, Deng F, Fu Y, Zhang Y, Wan H, Zhou D, Gu J, Xu J*. Pharmacokinetics and pharmacodynamics of subcutaneous injection and intravenous infusion of recombinant human interleukin-12 and recombinant human interleukin-12 combined with hepatitis B surface antigen in cynomolgus monkeys. Pharmacology. 2010;85(6):319-27.
15. Lin HB, Yang XM, Li TJ, Cheng YF, Zhang HT, Xu JP*. Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer's disease. Psychopharmacology (Berl). 2009;204(4):705-14.
