姓名：孙斌
单位：药学院
职称：副教授（六级岗），硕士生导师
邮箱：sunbb@smu.edu.cn
主要招生方向：工业药学
工作经历：
2013/12 – 至今， 南方医科大学
2010/05 – 2013/11，暨南大学，生命技术学院，博士后
学习经历：
2004/09–2009/07 中山大学，化学与化学工程学院，化学生物学专业，博士
2000/09–2004/07 中山大学，化学与化学工程学院，应用化学专业，学士
研究方向：
1. 基于金属配合物的放疗增敏药物的设计研究
2. 基于金属配合物的DNA纳米传感技术的研究
主持主要科研课题：
广东省自然科学基金面上项目 2026A1515011513 基于钌(II) 复合放疗增敏剂的cGAS-STING通路时空调控机制及构效关系研究，主持；
南医药学院青年科技人才项目续航计划-基于 X 射线响应钌(II)复合放疗增敏剂调控放射免疫研究，主持；
中山大学-生物无机与合成化学教育部重点实验室开放基金-基于脂质体包裹的金属钌(II)配合物复合放疗增敏剂研究，主持；
广东省普通高校特色创新类项目，基于P-DNA@Ru的精准靶向乳腺癌诊断治疗双功能探针的构建与研究，2018KTSCX028，主持；
南方医科大学创新驱动推进培育项目：基于金属配合物纳米复合体的乳腺癌诊断功能探针的构建与研究，主持；
6.国家自然科学基金青年项目，21401098，含氨基三嗪环的金属钌配合物抑制肺炎链
球菌靶标及其机制的研究，主持；
7.中国博士后基金，抗肿瘤钌多吡啶药物的研究 项目批准号：2011M501373，主持；
学术任职：
广东省化学会常务理事
发表论文
Lintao Wei‡,, Junjie Wang‡,, Jianhao Wu, Xidong Li, Qianying Zhou, Mengxu Sun, Bo Peng*, Jun Chen*, Bin Sun *, Cyclometalated Ruthenium (II) Complex-Based Nanoparticles for Enhanced microRNAs Detection and Imaging in Living Cells. BIOSENS BIOELECTRON 272 (2025) 117090（生物学1区，IF=10.7)
Jian Peng, Dong-Ling Quan, Guang Yang, Lin-Tao Wei, Zhuan Yang, Zhi-Ying Dong, Yi-Ming Zou, Ying-Ke Hou, , Jin-Xiang Chen, Lin Lv,*, Bin Sun,* Multifunctional Nanocomposites Utilizing Ruthenium (II) Complex/Manganese (IV) Dioxide Nanoparticle for Synergistic Reinforcing Radioimmunotherapy. Journal of Nanobiotechnology (2024) 22:735.（生物学1区，IF=10.6)
3.Yingke Hou,‡ Bin Sun,‡ Rongtian Li,‡Wei Meng, Wenhua Zhang, Nuan Jia,d Ming Chen,*Jinxiang Chen*and Xiaoyan Tang, GSH-activatable camptothecin prodrug-loaded gold nanostars coated with hyaluronic acid for targeted breast cancer therapy via multiple radiosensitization strategies. J. Mater. Chem. B, 2023,11.9894.
4.Pan,W.L., Tan,Y., Meng,W., Huang,N.H.,Zhao,Y.B,.Yu,Z.Q., Huang,Z., Zhang,W.H., Sun,B.,* Chen,J.X.,*Microenvironment-driven sequential ferroptosis, photodynamic therapy, and chemotherapy for targeted breast cancer therapy by a cancer-cell-membrane-coated nanoscale metal-organic framework. Biomaterials, 2022, 283.121449. （工程技术大类1区，IF=15.304)
5. Rong-Tian Li, Zhen Liang, Meng-Chu Li, Yong Tan, Bao-Ping Xie, Wen-Jun Duan, Chun-Tao Ning, Jin-Xiang Chen,* and Bin Sun,* Speedy, Specific, Synchronous Sensing Platforms with Ruthenium Complexes for Multiplexed MicroRNAs Detection. Inorg. Chem, 2020, 58, 15126-15137.(化学2区，IF=6.911)
6. Xiang-Ming Hu#, Rong-Tian Li#, Miao-Miao Zhang, Ke-Yang Wu, Huan-Huan Li, Nai-Han Huang, Bin Sun*, Jin-Xiang Chen* Phenanthroline-linked berberine dimer and fluorophore-tagged DNA conjugate for the selective detection of microRNA-185: experimental and molecular docking studies, Anal Chim Acta., 2019, 1051,153-159. (无机化学与核化学1区，IF=5.436)
7. Sun,B., Liang,Z., Xie,B.P., Li,L.Z., Li,R.T., Jiang,Z.H., Bai,L.P., Chen,J.X.,* Fluorescence sensing platform based on ruthenium(II) complexes as high 3S (sensitivity, specificity, speed) and “on-off-on” sensors for the miR-185 detection, Talanta, 2018,179, 658-667. (化学大类2区，分析化学2区，IF = 4.162)
8. Sun, B.; Zhao, H. Q.; Xie, B. P.; Bai, L. P.; Jiang, Z. H.; Chen, J. X*., Sequence-specific fluorometric recognition of HIV-1 ds-DNA with zwitterionic zinc(II)-carboxylate polymers. J. Inorg. Biochem. 2017, 176, 17-23. (IF = 3.348, ISSN: 0162-0134，生物大类3区，无机化学与核化学2区，生化与分子生物学3区)
9. Yang, X. Y.; Sun, B (共同作者).; Zhang, L.; Li, N.; Han, J.; Zhang, J.; Sun, X.; He, Q. Y*., Chemical interference with iron transport systems to suppress bacterial growth of Streptococcus pneumoniae. PLoS One. 2014, 9 (8), e105953. (IF = 2.806，ISSN:1932-6203生物大类3区，综合3区)
10. Sun, B. He, Q. Y*., Chemical Proteomics to Identify Molecular Targets of Small Compounds. Curr. Mol. Med. 2013, 13, 1175-1191. (IF = 3.521，ISSN: 1566-5240医学大类2区)
11. Bin Sun, Qing-Yu He*, Identification of Molecular Targets of Small Molecule Compounds by Chemical Proteomics, Current Molecular Medicine. 2013, 13, 1175-1191.
12. Bin Sun, Yu-Chuan Wang, Chen Qian, Jun Chu, Si-Min Liang, Hui Chao*, Liang-Nian Ji*, Synthesis, characterization and DNA-binding studies ofchiral ruthenium(II) complexes with 2-(5-nitrofuran-2-yl)-1H-imidazo[4,5-f][1,10]phenanthroline, Journal of Molecular Structure, 2010, 963, 153-159.
13. Bin Sun, Jing-Xin Guan, Li Xu, Bo-Le Yu, Long Jiang, Jun-Feng Kou, Li Wang, Xi-Dong Ding, Hui Chao*, and Liang-Nian Ji*, DNA Condensation Induced by Ruthenium(II) Polypyridyl Complexes [Ru(bpy)2(PIPSH)]2+ and [Ru(bpy)2(PIPNH)]2+, Inorganic. Chemistry., 2009, 48,4637-4649.
14. Bin Sun, Jun Chu, Yu Chen,Liang-Nian Ji*, Hui Chao*, Synthesis, characterization, electrochemical and photophysical properties of ruthenium(II) complexes containing 3-amino-1,2,4-triazino[5,6-f]-1,10-phenanthroline, Journal of Molecular Structure, 2008, 890, 203-208.
