吴耀彬 博士
副教授,硕士生导师
电子邮件: wuyaobin2018@smu.edu.cn
电 话:020-61648198
通讯地址:广东省广州市白云区沙太南路1023号(510515)
个人简介
吴耀彬,博士,南方医科大学基础医学院副教授,硕士研究生导师,中国科协青年人才托举工程入选者,欧盟“玛丽·居里学者”人才计划入选者,南方医科大学高层次引进人才。2012年7月毕业于西安交通大学,获得生物工程学士学位。2017年9月毕业于西安交通大学,获得生物医学工程博士学位,师从组织工程与再生医学领域著名学者Peter X Ma教授(密歇根大学终身教授)和郭保林教授。2017年10月至2018年2月于香港科技大学从事博士后研究工作,合作导师为生物制造领域著名学者Hongkai Wu教授。于2018年3月以高层次人次引进南方医科大学基础医学院。(Researchgate主页: https://www.researchgate.net/profile/Yaobin_Wu )
研究方向
主要从事导电弹性高分子、超分子自修复弹性材料、光固化弹性水凝胶等多种功能化柔弹性生物材料的设计及合成,并结合生物3D打印技术制备三维仿生支架用于神经、肌肉等软组织原位修复再生及体外仿生器官芯片构建等研究。近年来以第一作者或通讯作者Adv Funct Mater、ACS Nano、Biomaterials、Bioactive Materials等国际顶级杂志发表SCI论文共20余篇,其中影响因子10分以上的13篇,ESI高被引论文1篇。谷歌学术引用1800余次,H因子15。申请专利16项,其中授权8项。主持国家重点研发计划项目课题、国家自然科学基金项目、广东省自然科学基金、广州市科技局项目等共9项。担任Adv Funct Mater, Adv Healthc Mater, ACS AMI等国际顶级期刊评审专家。
研究关键词
柔性生物材料;生物3D打印;器官芯片;组织工程;再生医学
代表性著作
2018年至今发表的代表性论文:
1.Yu L#, Zeng G#, Xu J, Han M, Wang Z, Li T, Long M, Wang L*, Huang W*, Wu Y*,Development of Poly(glycerol sebacate) and its Derivatives: a Review of the Progress over the Past Two Decades. Polymer Reviews. 2022. (DOI: 10.1080/15583724.2022.2150774), In Press(*共同通讯, JCR一区,影响因子:14.536)
2. X. Cheng, P. Yin, T. Li, L. Luo, Y. Yang, L. Wang, W. Su, Y. Wang, Y. Li, Y. Wang*, Wu Y*, W. Huang*, Injectable Composite Hydrogel Encapsulating Gelatin Methacryloyl/Chitosan Microspheres as ARPE-19 Cell Transplantation Carriers, Biomater Sci. (2022). https://doi.org/10.1039/d2bm01413k. In Press(*共同通讯, JCR二区,影响因子:7.590)
3. Li T, Hou J, Wang L, Zeng G, Wang Z, Yu L, Yang Q, Yin J, Long M, Chen L, Chen S, Zhang H, Li Y, Wu Y*, Huang W*. Bioprinted Anisotropic Scaffolds with Fast Stress Relaxation Bioink for Engineering 3D Skeletal Muscle and Repairing Volumetric Muscle Loss. Acta Biomater. 2022. (DOI: 10.1016/j.actbio. 2022.08.037) In Press, (*共同通讯, JCR一区,影响因子:10.633)
4. Yin J, Zhong J, Wang J, Wang Y, Li T, Wang L, Yang Y, Zhen Z, Li Y, Zhang H, Zhong S*, Wu Y*, Huang W*, 3D-printed high-density polyethylene scaffolds with bioactive and antibacterial layer-by-layer modification for auricle reconstruction, Mater Today Bio. (2022) 100361. (*共同通讯, JCR一区,影响因子:10.761)
5.Wang L, Li T, Wang Z, Hou J, Liu S, Yang Q, Yu L, Guo W, Wang Y, Guo B*, Huang W*, WuY*, Injectable remote magnetic nanofiber/hydrogel multiscale scaffold for functional anisotropic skeletal muscle regeneration, Biomaterials. 285 (2022) 121537. (*共同通讯, JCR一区,影响因子:15.304)
6.Chen P, Ning X, Li W, Pan Y, Wang L, Li H, Fan X, Zhang J, Luo T, Wu Y*, Ou C*, Chen M*, Fabrication of Tβ4-Exosome-releasing artificial stem cells for myocardial infarction therapy by improving coronary collateralization, Bioact Mater. (2022). (*共同通讯, JCR一区,影响因子:16.874)
7.Wu X#, Guo W#, Wang L#, Xu Y, Wang Z, Yang Y, Yu L, Huang J, Li Y, Zhang H, Wu Y*, Li G*, Huang W*, An Injectable Asymmetric‐Adhesive Hydrogel as a GATA6+ Cavity Macrophage Trap to Prevent the Formation of Postoperative Adhesions after Minimally Invasive Surgery, Adv Funct Mater. (2021) 2110066. (*共同通讯, JCR一区,影响因子:19.924)
8. Wang Z#, Wang L#, Li T, Liu S, Guo B, Huang W*, Wu Y*, 3D Bioprinting in Cardiac Tissue Engineering, Theranostics, 2021; 11(16):7948-7969. (*共同通讯, JCR一区,影响因子:11.600)
9.L. Lin#, Y. Wang#, L. Wang, J. Pan, Y. Xu, S. Li, D. Huang, J. Chen, Z. Liang, P. Yin, Y. Li, H. Zhang, Y. Wu*, C. Zeng*, W. Huang*, Injectable microfluidic hydrogel microspheres based on chitosan and poly(ethylene glycol) diacrylate (PEGDA) as chondrocyte carriers, Rsc Adv. 10 (2020) 39662–39672. (*共同通讯, JCR三区,影响因子:4.036)
10.Chen J, Huang D, Wang L, Hou J, Zhang H, Li Y, Zhong S*, Wang Y, Wu Y*, Huang W*. 3D Bioprinted Multiscale Composite Scaffolds Based on Gelatin Methacryloyl (GelMA)/Chitosan Microspheres as a Modular Bioink for Enhancing 3D Neurite Outgrowth and Elongation. J Colloid Interf Sci,2020,574:162-173 (*共同通讯, JCR一区,影响因子:9.965)
11.Wang L,Wu Y*, Hu T, Ma PX, Guo B*. Aligned Conductive Core-Shell Biomimetic Scaffolds Based on Nanofiber Yarns/Hydrogel for Enhanced 3D Neurite Outgrowth Alignment and Elongation. Acta Biomater.2019,96:175-187 (*共同通讯, JCR一区,影响因子:10.633)
12. Hu T#, Wu Y#, Zhao X, Wang, L, Bi, L, Ma, PX, Guo, B. Micropatterned, electroactive, and biodegradable poly(glycerol sebacate)-aniline trimer elastomer for cardiac tissue engineering. Chem Eng J. 2019,366: 208-222. (#共同一作,JCR一区,影响因子:13.273)
13. Naik AR, Pernal S, Lewis KT, Wu Y, Wu H, Carruthers NJ, Stemmer PM, Jena BP, Human skeletal muscle cells on engineered 3D platform express key growth and developmental proteins. ACS Biomater Sci Eng. 2019, 5 (2):970–976 (JCR二区,影响因子:5.395)
14.Wu Y, Wang L, Tianli H, Guo B*, Ma PX*. Conductive micropatterned polyurethane films as tissue engineering scaffolds forSchwann cells and PC12 cells, J Colloid Interf Sci, 2018, 518: 252-262 (JCR一区,影响因子:9.965)
2018年之前发表的代表性论文:
15. Wu Y#, Wang L#, Guo B*, Ma PX. Interwoven aligned conductive nanofiber yarn/hydrogel composite scaffolds for engineered 3D cardiac anisotropy. ACS Nano. 2017,11:5646-59. (JCR一区,影响因子:18.027)
16.Wu Y#, Wang L#, Zhao X, Hou S, Guo B*, Ma PX*. Self-healing supramolecular bioelastomers with shape memory property as a multifunctional platform for biomedical applications via modular assembly. Biomaterials. 2016,104:18-31. (JCR一区,影响因子:15.304)
17.Wu Y#, Wang L#, Guo B*, Shao Y, Ma PX*. Electroactive biodegradable polyurethane significantly enhanced Schwann cells myelin gene expression and neurotrophin secretion for peripheral nerve tissue engineering. Biomaterials. 2016,87:18-31. (JCR一区,影响因子:15.304)
18. Wu Y, Guo B*, Ma PX*. Injectable electroactive hydrogels formed via host–guest interactions. ACS Macro Lett. 2014,3:1145-50. (JCR一区,影响因子:7.015)
19.Wu Y, Wang L, Guo B, Ma PX. Injectable biodegradable hydrogels and microgels based on methacrylated poly(ethylene glycol)-co-poly(glycerol sebacate) multi-block copolymers: synthesis, characterization, and cell encapsulation. J Mater Chem B. 2014,2:3674-85. (JCR一区,影响因子:7.571)
20.Wang L#, Wu Y#, Guo B*, Ma PX*. Nanofiber yarn/hydrogel core–shell scaffolds mimicking native skeletal muscle tissue for guiding 3D myoblast alignment, elongation, and differentiation. ACS Nano. 2015,9:9167-79. (#共同一作,JCR一区,影响因子:18.027)
21.Wang L, Wu Y, Hu T, Guo B*, Ma PX*. Electrospun conductive nanofibrous scaffolds for engineering cardiac tissue and 3D bioactuators. Acta Biomater. 2017,59:68-81. (JCR一区,影响因子:10.633)
代表性课题
1.国家重点研发计划项目课题,555万(中央经费105万),主持,2022.12—2026.11
2.国家自然科学基金项目-面上项目,54万,主持,2023.01—2026.12
3.国家自然科学基金项目-青年项目,25万,主持,2020.01—2022.12
4.粤桂联合基金-面上项目,10万,主持, 2020.12—2023.11
5.广东省基础与应用基础研究基金项目-面上项目,10万,主持, 2019.01—2022.09
6.广东省区域联合基金项目-重点项目子课题,10万,主持,2021.10—2024.09
7.广州市科技计划项目-基础与应用基础研究项目,5万,主持,2021.04—2023.03
8.欧盟“玛丽·居里学者”人才计划(MSCA),23万欧元(约160万人民币),主持,2023.06—2025.05
9.中国科学技术协会,中国科协第七届(2021-2023 年度)青年人才托举项目,45万,主持,2022.04—2023.12
学术任职
中国医药生物技术协会3D打印技术分会委员,并兼任材料学组秘书;《中国组织工程研究》杂志社医工融合联盟委员;广东省精准医学应用学会医工结合分会委员。
执教课程(课程及教材建设)
必修课:《系统解剖学》
选修课:《奇妙的人体世界》
《解剖学技术(第三版)》编委
荣誉奖励
1. 第一届中国科技青年论坛二等奖(2022年9月)
2. 中国科协第七届(2021-2023 年度)青年人才托举项目;
3. 欧盟“玛丽·居里学者”人才计划(Marie Skłodowska Curie Fellow,UKRI funded @ Imperial College London)