黄文华博士

教授，博士生导师

广东省医学生物力学重点实验室主任

电子邮件:huangwenhua2009@139.com

电话：020-61648361

通讯地址：广东省广州市白云区沙太南路1023号（510515）

个人简介

个人教育	起止年月	校（院）、系及专业	学位
	1990.09-1994.06	第一军医大学，生物医学工程	学士
	1994.09-1998.06	第一军医大学，生物医学工程	硕士
	1998.09-2001.06	第一军医大学，人体解剖与组织胚胎学	博士
	1999.02-2000.03	清华大学，生物医学工程	访问学者
工作经历	起止年月	工作单位	职务
	2001.07-2004.03	第一军医大学	讲师
	2004.03-2009.08	南方医科大学	副教授
	2006.12-2008.12	南方医科大学附属江都医院	挂职副院长
	2009.08- 至今	南方医科大学	教授
	2010.03-2010.06	南方医科大学人体解剖学国家重点学科	科室副主任
	2010.06-2012.12	南方医科大学基础医学院	副院长
	2012.12-2017.06	南方医科大学基础医学院	院长
	2017.06-2020.04	南方医科大学教务处	处长
	2020.04-至今	南方医科大学研究生院	常务副院长

研究方向

临床应用解剖学、数字医学及医学3D打印

研究关键词

临床解剖；医学3D打印；生物医学工程；数字骨科

Clinical anatomy; Medical three-dimensional printing; Biomedical engineering; Digital orthopedics

代表性论著

1.Xu Y, Chen W, Liang J, Zeng X, Ji K, Zhou J, Liao S, Wu J, Xing K, He Z, Yang Y, Liu Q, Zhu P, Liu Y, Li L, Liu M, Chen W, Huang W*. The miR-1185-2-3p-GOLPH3L pathway promotes glucose metabolism in breast cancer by stabilizing p53-induced SERPINE1. J Exp Clin Cancer Res. 2021, 40(1):47（IF=4.553  JCR2区）

2.Zheng Z, Lei X, Yang Y, Tan X, Cheng B, Huang W*. Changes in Human Fat Injected Alongside Hyaluronic Acid in the Backs of Nude Mice. Aesthet Surg J. 2021, 41(6):NP631-NP642(IF=4.283 JCR2区)

3.Liu H, Li T, Zhong S, Yu M*, Huang W*. Intestinal epithelial cells related lncRNA and mRNA expression profiles in dextran sulphate sodium-induced colitis. J Cell Mol Med. 2021, 25(2):1060-1073(IF=6.216 JCR2区)

4.Zhang Y, Ma L, Lu E*, Huang W*. Atorvastatin Upregulates microRNA-186 and Inhibits the TLR4-Mediated MAPKs/NF-??B Pathway to Relieve Steroid-Induced Avascular Necrosis of the Femoral Head. Front Pharmacol. 2021, 12:583975(IF=5.810 JCR1区)

5.Zheng Z, Hao Y, Yin J, Lei X, Cheng B, Huang W*. Autogenous Fat Transplantation and Botulinum Toxin Injection Into the Masseter Muscle to Create an Ideal Oval Face. Aesthet Surg J. 2021, 41(6):NP579-NP588 （IF=4.283 JCR2区）

6.Huang X, Lin D, Liang Z, Deng Y, He Z, Wang M, Tan J, Li Y, Yang Y*, Huang W*. Mechanical Parameters and Trajectory of Two Chinese Cervical Manipulations Compared by a Motion Capture System. Front Bioeng Biotechnol. 2021, 9:714292（IF=5.890 JCR1区）

7.Xu L, Qin H, Tan J, Cheng Z, Luo X, Tan H*, Huang W*. Clinical study of 3D printed personalized prosthesis in the treatment of bone defect after pelvic tumor resection. J Orthop Translat. 2021, 29:163-169（IF=5.191 JCR1区）

8.Chen J, Huang D, Wang L, Hou J, Zhang H, Li Y, Zhong S, Wang Y, Wu Y*, Huang W*. 3D bioprinted multiscale composite scaffolds based on gelatin methacryloyl (GelMA)/chitosan microspheres as a modular bioink for enhancing 3D neurite outgrowth and elongation. J Colloid Interface Sci. 2020, 574:162-173 （IF=8.128 JCR1区 ）

9.Zhan J, Zhong J, Ma S, Ma W, Wang Y, Yu Z, Cai Y*, Huang W*. Dual-responsive self-assembly in lysosomes enables cell cycle arrest for locking glioma cell growth. Chem Commun (Camb). 2020, 56(51):6957-6960（IF=6.222 JCR1区）

10.Ma L, Cheng S, Ji X, Zhou Y, Zhang Y, Li Q, Tan C, Peng F, Zhang Y*, Huang W*. Immobilizing magnesium ions on 3D printed porous tantalum scaffolds with polydopamine for improved vascularization and osteogenesis. Mater Sci Eng C Mater Biol Appl. 2020, 117:111303（IF=4.051 JCR2区）

11.Combining Chrominance Features and Fast ICA for Noncontact Imaging Photoplethysmography. IEEE ACCESS. 3.737, JCR Q2, 2020（通讯）（IF=3.367 JCR1区）

12.Lv SD, Wang HY, Yu XP, Zhai QL, Wu YB, Wei Q*, Huang WH*. Integrative molecular characterization of Chinese prostate cancer specimens. Asian J Androl. 2020, 22(2):162-168（IF=3.285 JCR2区）

13.Li Y, Wang Y, Wang Y, Wang H, Li D, Chen Q*, Huang W*. Impaired Topological Properties of Gray Matter Structural Covariance Network in Epilepsy Children With Generalized Tonic-Clonic Seizures: A Graph Theoretical Analysis. Front Neurol. 2020, 11:253（IF=4.00 JCR4区）

14.Huang X, Ye L, Liu X, Weng R, Tan J, Xie P, Yang Y, Liang L, Huang W*, Jiang X. The relationship between facet tropism and cervical disc herniation. J Anat. 2020, 236(5):916-922（IF=2.610 JCR1区）

15.Chen J, Huang D, Wang L, Hou J, Zhang H, Li Y, Zhong S, Wang Y, Wu Y, Huang W*. 3D bioprinted multiscale composite scaffolds based on gelatin methacryloyl (GelMA)/chitosan microspheres as a modular bioink for enhancing 3D neurite outgrowth and elongation. J Colloid Interface Sci. 2020, 574:162-173（IF=8.128 JCR1区）

16.Liu X, Wang Y, Zhang H, Yin Y, Cao K, Gao Z, Liu H, Hau WK, Gao L, Chen Y, Cao F*, Huang W*. Evaluation of fractional flow reserve in patients with stable angina: can CT compete with angiography? Eur Radiol. 2019, 29(7):3669-3677（IF=5.315 JCR1区）

17.Wang Y, Li S, Liu M, Wang J, Fei Z, Wang F, Jiang Z, Huang W, Sun H. Rhodosporidium toruloides sir2-like genes remodelled the mitochondrial network to improve the phenotypes of ageing cells. Free Radic Biol Med. 2019, 134:64-75（IF=7.376 JCR1区）

18.Liu X, Wang Y, Zhang H, Yin Y, Cao K, Gao Z, Liu H, Hau WK, Gao L, Chen Y, Cao F, Huang W*. Evaluation of fractional flow reserve in patients with stable angina: can CT compete with angiography? Eur Radiol. 2019, 29(7):3669-3677（IF=5.315 JCR1区）

19.Li S, Fei Z, Xu Z, Wang J, Jiang Z, Xie Y, Wang Y, Huang W, Sun H. Enterococcus faecalis sir2-like gene enhances aerobic metabolism of themselves and mitochondrial respiration of mammal cells to bring about improving metabolic syndrome through the PGC-1?? pathway. J Tissue Eng Regen Med. 2019, 13(2):143-155（IF=4.169 JCR4区）

20.Wang J, Zhang L, Qu R, Zhang L*, Huang W*. Rho A Regulates Epidermal Growth Factor-Induced Human Osteosarcoma MG63 Cell Migration. Int J Mol Sci. 2018, 19(5):（IF=5.923 JCR2区）

21.Zhong E, Zhao Q, Shi B, Xie Y, Ding Z, Lv H, Zhong S, Huang W*. The Morphology and Possible Clinical Significance of the Intraforaminal Ligaments in the Entrance Zones of the L1-L5 Levels. Pain Physician. 2018, 21(2):E157-E165（IF=4.965 JCR2区）

22.Xu P, Liu X, Zhang H, Ghista D, Zhang D, Shi C, Huang W*. Assessment of boundary conditions for CFD simulation in human carotid artery. Biomech Model Mechanobiol. 2018, 17(6):1581-1597（IF=2.963 JCR2区）

23. Ling Q, He E, Ouyang H, Guo J, Yin Z, Huang W*. Design of mulitlevel OLF approach ("V"-shaped decompressive laminoplasty) based on 3D printing technology. Eur Spine J. 2018, 27(suppl 3):323-329（IF=3.134 JCR3区）

24.Li Y, Tan Z, Wang J, Wang Y, Gan Y, Wen F, Chen Q, Abbott D, Wong KKL*, Huang W*. Alterations in Spontaneous Brain Activity and Functional Network Reorganization following Surgery in Children with Medically Refractory Epilepsy: A Resting-State Functional Magnetic Resonance Imaging Study. Front Neurol. 2017, 8:374（IF=4.003 JCR3区）

25.Shen S, Zhong S, Xiao G, Zhou H, Huang W. Parity association with clinicopathological factors in invasive breast cancer: a retrospective analysis. Onco Targets Ther. 2017, 10:477-481（IF=4.147 JCR2区）

26.Wang Y, Li Y, Wang H, Chen Y, Huang W*. Altered Default Mode Network on Resting-State fMRI in Children with Infantile Spasms. Front Neurol. 2017, 8:209（IF=4.003 JCR3区）

27.28.Zhong E, Zhao Q, Shi B, Zheng X, Zhao Q, Tan J, Ding Z, Huang W. Morphology and Possible Clinical Significance of the Radiating Extraforaminal Ligaments at the L1-L5 Levels[J]. Spine (Phila Pa 1976). 2017, 42(18): 1355-1361.（IF=3.468 JCR2区）

28.Yu Z, Zhang G, Chen X, Chen X, Wu C, Lin Y, Huang W, Lin H. Application of a novel 3D drill template for cervical pedicle screw tunnel design: a cadaveric study[J]. Eur Spine J. 2017, 26(9): 2348-2356.（IF=3.134 JCR3区）

29.Huang P, Zeng B, Mai Z, Deng J, Fang Y, Huang W, Zhang H, Yuan J, Wei Y, Zhou W. Novel drug delivery nanosystems based on out-inside bifunctionalized mesoporous silica yolk–shell magnetic nanostars used as nanocarriers for curcumin[J]. J Mater Chem B,2016, 4(1): 46-56.（IF=6.331 JCR1区）

30.Liu X, Zhang H, Ren L, Xiong H, Gao Z, Xu P, Huang W, Wu W. Functional assessment of the stenotic carotid artery by CFD-based pressure gradient evaluation[J]. Am J Physiol-Heart C, 2016, 311(3): H645-H653.（IF=4.733 JCR2区）

代表性课题

1.新型仿生三维多孔结构聚乙烯耳廓支架的构建及实验研究，国基金面上项目，58万元，2023.12

2.生物3D打印仿生结构建模与组织功能重建机制研究，国家重点研发计划课题，1146万元

3.活体肿瘤组织代谢信号多参数时空动态成像系统研究，国基金重大科研仪器研制课题，204万元

4.新型仿生三维多孔结构聚乙烯耳廓支架的构建及实验研究，国基金国际(地区)合作与交流项目，10万元，2023.03

5.面向3D打印的数字医学技术支持中心建设及应用示范，广东省科技计划，1800万元

6.3D打印C/GP/Co水凝胶共缓释TGF-β2和BMP-2重建关节软骨的研究，广东省基础与应用基础研究基金粤莞联合基金重点项目，20万元，2023.09

学术任职

1. 中国医药生物技术协会医学3D打印技术分会主任委员