邱小忠博士

教授，博士生导师

教研室副主任

广东省组织构建与检测重点实验室主任

电子邮件:qiuxzh@smu.edu.cn

电话：020-61648401

通讯地址：广东省广州市白云区沙太南路1023号（510515）

个人简介

教育经历（按时间倒序排序）：

1998/8-2001/1，第一军医大学，生物化学与分子生物学，博士，

研究方向：自由基医学。导师：陈瑗教授。

1995/8-1998/7，中山大学，植物学，硕士，

研究方向：分子系统进化，导师：施苏华教授

1988/9-1992/7，江西大学，生物学，学士

科研与学术工作经历（按时间倒序排序）：

2012/12 - 至今，南方医科大学，基础医学院，教授

2006/12 - 2012/12，南方医科大学，基础医学院，副教授

2001/6 - 2006/12，南方医科大学，基础医学院，讲师

研究方向

生物材料与组织工程

研究关键词

组织工程（Tissue Engineering）,生物材料（Biomaterials）

代表性论著

1. Xiaoping Song#, Xiaorui Wang#, Jie Zhang, Si Shen, Wenming Yin, Genlan Ye, Leyu Wang, Honghao Hou, Xiaozhong Qiu*（独立通讯）. A tunable self-healing ionic hydrogel with microscopic homogeneous conductivity as a cardiac patch for myocardial infarction repair. Biomaterials,2021, 273:120811

2. Yutong He#, Honghao Hou#, Shuqi Wang#, Rurong Lin, Leyu Wang, Lei Yu, Xiaozhong Qiu*（独立通讯）. From waste of marine culture to natural patch in cardiac tissue engineering. Bioactive Materials,2020, 10(5):2047-2066

3. Genlan Ye#, Zubiao Wen#, Feng Wen, Xiaoping Song, Leyu Wang, Chuangkun Li, Yutong He, Sugandha Prakash, Xiaozhong Qiu*（独立通讯）. Mussel-inspired conductive Ti2C-cryogel promotes functional maturation of cardiomyocytes and enhances repair of myocardial infarction. Theranostics. 2020; 10(5):2047-2066. 

4. Song X#, Mei J#, Ye G, Wang L, Ananth A, Yu L, Xiaozhong Qiu*.（独立通讯）In situ pPy-modification of chitosan porous membrane from mussel shell as a cardiac patch to repair myocardial infarction. Applied Materials Today. 2019, 15: 87-99.

5. Chen Song#, Xingying Zhang#, Leyu Wang*, Feng Wen, Kaige Xu, Weirong Xiong, Chuangkun Li, Bingyun Li, Quan Wang, Malcolm M. Q. Xing* and Xiaozhong Qiu*（最后通讯）. An Injectable Conductive Three-Dimensional Elastic Network by Tangled Surgical-Suture Spring for Heart Repair. ACS Nano 2019, 13, 14122-14137. 

6. Xiaoliang Zhao#, Huiyong Xu#, Genlan Ye, Chuangkun Li, Leyu Wang*, Fang Hu* and Xiaozhong Qiu*（最后通讯）. Temperature-activated PRP–cryogel for long-term osteogenesis of adipose-derived stem cells to promote bone repair. Materials. Chemistry Frontiers, 2021, 5, 396-405.

7. Song X#, Mei J#, Zhang X, Wang L, Singh G, Xing MMQ*, Xiaozhong Qiu*（最后通讯）.Flexible and highly interconnected, multi-scale patterned chitosan porous membrane produced in situ from mussel shell to accelerate wound healing. Biomater Sci. 2017,5(6):1101-1111.

8. Zheyu Shen, Ting Liu, Zhen Yang, Zijian Zhou, Wei Tang, Wenpei Fan, Yijing Liu, Jing Mu, Ling Li, Vladimir I. Bregadze, Swadhin K. Mandal, Anna A. Druzina, Zhenni Wei, Xiaozhong Qiu*（并列通讯）, Aiguo Wu*, Xiaoyuan Chen*. Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma. Biomaterials. 2020,235:119783. 

9. Wei Zhenni#, Jiang Zhenqi, Pan Chunshu, Xia Jianbi, Xu Kaiwei, Xue Ting, Yuan Bo, Akakuru Ozioma Udochukwu, Zhu Chengjie, Zhang Guilong, Mao Zheng, Qiu Xiaozhong*（并列通讯）, Wu Aiguo*, Shen Zheyu*. Ten-Gram-Scale Facile Synthesis of Organogadolinium Complex Nanoparticles for Tumor Diagnosis. Small, 2020, 16(11): 1906870. 

10. Jiewen Li#, Meng Zhang, Minggui Wan, Chunli Lin, Shihong Huang, Cuihong Liu, Qingping He, Xiaozhong Qiu*（并列通讯）, Xiaohui Fang*. Ultrasensitive refractive index sensor based on enhanced Vernier effect through cascaded fiber core-offset pairs. Optics Express, 2020, 28(3): 4145-4155.

11. Leyu Wang#, Xingying Zhang#, Yutong He, Ying Wang, Wen Zhong, Kibret Mequanint, Xiaozhong Qiu（并列通讯）,* and Malcolm Xing*. Ultralight Conductive and Elastic Aerogel for Skeletal Muscle Atrophy Regeneration. Adv Funct Mater, 2019, 29(1): 1806200.

12. Xiaotong Wang#, Leyu Wang#, Qiang Wu, Feng Bao, Huangtian Yang*, Xiaozhong Qiu*（并列通讯）, Jiang Chang*. Chitosan/Calcium Silicate Cardiac Patch Stimulates Cardiomyocyte Activity and Myocardial Performance after Infarction by Synergistic Effect of Bioactive Ions and Aligned Nanostructure. ACS Appl. Mater. Interfaces, 2019, 11(1): 1449-1468. 

13. Yutong He#, Genlan Ye#, Chen Song, Chuangkun Li, Weirong Xiong, Lei Yu, Xiaozhong Qiu*（并列通讯）, Leyu Wang*. Mussel-inspired conductive nanofibrous membranes repair myocardial infarction by enhancing cardiac function and revascularization. Theranostics. 2018; 8(18):5159-5177. 

14.Xiangling Ren，JiejieGe, XianweiMeng*, XiaozhongQiu*, Jun Ren, FangqiongTang. Sensitive detection of dopamine and quinone drugs based on the quenching of the fluorescence of carbon dots. Science Bulletin, 2016,61(20):1615-1623.

15. Leyu Wang(#)，Junzi Jiang(#)，Wenxi Hua，Ali Darabi，Xiaoping Song，Chen Song， Wen Zhong，Malcolm Xing*, Xiaozhong Qiu*.Mussel-Inspired Conductive Cryogel as Cardiac Tissue Patch to Repair Myocardial Infarction by Migration of Conductive Nanoparticles. Advanced Functional Materials，2021, 7(3):370

16. Guobao Wang, Tingting Zhao, Leyu Wang, Bianxiang Hu,Ali Darabi, Jiansheng Lin, Malcolm Xing *,Xiaozhong Qiu*. Studying different binding and intracellular delivery efficiency of ssDNA -single-walled carbon nanotube and their effects on LC3-related autophagy in renal mesangial cells via miRNA-382. ACS Applied Materials & Interfaces. 2015, 7(46):25733-25740

17. Jiang, Xinglu#，Wang, Guobao，Liu, Ru，Wang, Yaling，Wang, Yongkui，Qiu Xiaozhong*，Gao, Xueyun*. RNase non-sensitive and endocytosis independent siRNA delivery system: delivery of siRNA into tumor cells and high efficiency induction of apoptosis. Nanoscale，2013, 5(16):7256-7264

代表性课题

1. 广州市科技计划重点项目，2018.04-2021.03，主持。

2. 广东省省级科技计划项目，2017.07-2020.06，主持。

3. 国家自然科学基金应急管理项目，2018-09- 2018-12-31，主持。

4. NSFC-广东省联合基金重点项目，2017.1-2020.12，主持。

5. 国家自然科学基金面上项目，2016.1-2019.12，主持。

6. 国家自然科学基金面上项目，2014.1-2017.12，主持。

7. 国家自然科学基金面上项目，2008.01-2010.12，主持。

8. 国家自然科学基金专项基金项目，2013.6-2014.5，主持。

9. 国家自然科学基金海外合作合作项目，2015.01-2016.12，中方主持人。

10. 广州市科技计划项目，20011-2013，主持。

11. 广东省科技计划项目重大专项，2016-2019，主持人之一。

学术任职

中国医药生物技术协会纳米生物技术分会委员；中国人体解剖学会血管学分会常务理事；广东省生物物理学会常务理事；广东省生物医学工程学会生物材料专业委员会副主任委员；“中国临床解剖学杂志”编委。

执教课程（课程及教材建设）

组织工程学、系统解剖学、神经解剖学

荣誉奖励

2016年，获广东省特支计划百千万工程领军人才荣誉称号