陆滟霞 博士
教授,硕士生导师
电子邮件:luzyanyar@163.com
电 话:
通讯地址:广东省广州市白云区沙太南路1023号(510515)
研究方向
结直肠癌转移机制;抗结直肠癌免疫机制及免疫治疗
研究关键词
结直肠癌;转移;免疫微环境;肿瘤新抗原;免疫治疗
Colorectal cancer,metastasis,immune cells,Neoantigen,immunotherapy
代表性论著
1、Lu YX, Yuan L, Xue XL, Zhou M, Liu Y, Zhang C, Li JP, Zheng L, Hong M, Li XN*. Regulation of colorectal carcinoma stemness, growth, and metastasis by an miR-200c-Sox2-negative feedback loop mechanism. Clin Cancer Res. 2014 May 15;20(10):2631-42.(IF=10.107,JCR1区)
2、Lu Y#, Yang H#, Yuan L#, Liu G#, Zhang C, Hong M, Liu Y, Zhou M, Chen F, Li X*.Overexpression of miR-335 confers cell proliferation and tumour growth to colorectal carcinoma cells. Mol Cell Biochem.2016 Jan; 412(1-2)235-45 (IF=2.795,JCR3区)
3、Chun Lin# , Jianming Zhang#, Yanxia Lu# , Xiaomin Li , Wenjuan Zhang , Wei Zhang, Weihao Lin , Lin Zheng and Xuenong Li*.NIT1 suppresses tumour proliferation by activating the TGFβ1-Smad2/3 signalling pathway in colorectal cancer. Cell Death Dis. 2018 Feb 15;9(3):263(IF=6.304,JCR2区)
4、Wei Zhang#, Yanxia Lu# , Xiaomin Li#, Jianming Zhang, Lin Zheng,Wenjuan Zhang , Chun Lin, Weihao Lin, Xuenong Li*.CDCA3 promotes cell proliferation by activating the NF-kB/cyclin D1signaling pathway in colorectal cancer. Biochemical and Biophysical Research Communications. 2018April; 500: 196-203(IF=2.985,JCR3区)
5、Wenjuan Zhang# , Yanxia Lu , Xiaomin Li , Jianming Zhang, Weihao Lin , Wei Zhang , Lin Zheng and Xuenong Li*. IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation.. J Exp Clin Cancer Res. 2019 Jul; 38(1):296. (IF=7.068,JCR2区)。
代表性课题
1、国家自然科学基金委员会,青年基金项目,2016-01至2018-12,18.5万元,已结题,主持;
2、广东省自然科学基金管理委员会,博士启动项目,2015-01至2018-01,10万元,已结题,主持;
3、广东省自然科学基金管理委员会,面上项目,2019-10至2022-08,10万元,在研,主持
学术任职
广东省粤港澳合作促进会医药卫生大健康委员会病理联盟第一届委员会委员
执教课程(课程及教材建设)
病理学