邓永强博士
教授,博士生导师
电子邮件:york6332@163.com
电话:020-61648172
通讯地址:广东省广州市白云区沙太南路1023号(510515)
个人简介
教育经历:
2007.09-2012.07 中国科学院,生物物理研究所,博士
2003.09-2007.07 武汉大学,生命科学院生物技术基地班,学士
工作经历:
2020.01-至今 南方医科大学,基础医学院病生教研室,教授
2019.07-2019.12耶鲁大学医学院,细胞生物系,Research Scientist
2018.01-2019.06耶鲁大学医学院,细胞生物系,Associate Research Scientist
2012.09-2017.12耶鲁大学医学院,细胞生物系,博士后
研究方向
鞘脂的代谢与转运对细胞功能的影响;高尔基体蛋白分选与蛋白分泌;脓毒症
研究关键词
membrane trafficking;sphingolipid;sepsis;golgi;secretion
代表性论著
1.Deng Yongqiang#; Pakdel Mehrshad#; Blank Birgit; Sundberg Emma L; Burd Christopher G*; von Blume Julia*; Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network, Developmental Cell, 2018, 47(4): 464-478. (IF 10.1,JCR 1区)
2.Deng Yongqiang; Rivera-Molina Felix E; Toomre Derek K; Burd Christopher G*; Sphingomyelin is sorted at the trans Golgi network into a distinct class of secretory vesicle, Proc Natl Acad Sci U S A, 2016, 113(24): 6677-6682. (IF 9.4,JCR 1区)
3.Cai Yiying#; Deng Yongqiang#; Horenkamp Florian; Reinisch Karin M*; Burd Christopher G*; Sac1-Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus, J Cell Biol, 2014, 206(4): 485-491. (IF 8.8,JCR 2区)
4.Li Zhengzheng#; Liu Lin#; Deng Yongqiang#; Ji Wei; Du Wen; Xu Pingyong; Chen Liangyi*; Xu Tao*; Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits, Cell Res, 2010.02, 21(2): 305-315.(IF 20.5,JCR 1区)
5.Emma L. Sundberg; Yongqiang Deng; Christopher G. Burd*; Syndecan-1 Mediates Sorting of Soluble Lipoprotein Lipase with Sphingomyelin-Rich Membrane in the Golgi Apparatus, Developmental Cell, 2019, 51(3): 387-398. (IF 10.1,JCR 1区)
代表性课题
国家自然科学基金面上项目,58万,2022.01-2025.12,主持
执教课程
现代仪器分析与应用、蛋白质组学