宋千成 博士

副教授

电子邮件: songqc@smu.edu.cn

电 话：020-61647584

通讯地址：广东省广州市白云区沙太南路1023号（510515）

个人简介

宋千成，副教授，硕士生导师。近年承担国家自然科学基金、广东省自然科学基金、广东省重点实验室开放课题等课题，主要从事中枢神经损伤与修复、骨生物学相关研究，以第一作者或通讯作者在Nature Communications (IF = 14.919)、Cancer Research (IF = 12.701)、Cancer Biomarkers、Oncotarget等杂志发表研究性论文，单篇最高他引130余次。

研究方向

中枢神经损伤与修复、骨生物学

研究关键词

细胞信号转导cell signal transduction、骨生物学 bone biology、

中枢神经损伤与修复 injury and repair in central nervous system

代表性论著

1. Xia W#, Xie J#, Cai Z#, Liu X, Wen J, Cui Z, Zhao R, Zhou X, Chen J, Mao X, Gu Z, Zou Z, Zou Z, Zhang Y, Zhao M, Mac M, Song Q*, Bai X*. Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors. Nat Commun. 2021 Oct 15; 12(1):6043. (IF:14.919) （该成果受到基金委网站报道，并被 “Faculty Opinions (原F1000)”列为推荐论文）

2. Song Q#, Xu X, Yang C, Chen Z, Jia C, Chen J, Zhang Y, Lai P, Fan X, Zhou X, Lin J, Li M, Luo S, Gao T, Bai X*, miR-483-5p, a beta-catenin-activated microRNA, promotes lung adenocarcinoma invasion and metastasis by targeting RhoGDI1 and ALCAM, Cancer Res, 2014 Jun 1;74(11):3031-42. (IF:12.701) 被引用135次

3. Xiao M^#, Zhang W^#, Li W^#, Mao L, Yang J, Hu L, Zhang S, Zheng Y, Liu A, Song Q, Li Y, Xiao G, Zou Z*, Bai X*. Osteocytes regulate neutrophil development through IL-19: A potent cytokine for neutropenia treatment. Blood. 2021 Jun 24; 137(25): 3533-3547. (IF: 22.113)

4. Li K, Zhang Y, Zhang Y, Jiang W, Shen J, Xu S, Cai D, Shen J, Huang B, Li M, Song Q, Jiang Y, Liu A, Bai X*. Tyrosine kinase Fyn promotes osteoarthritis by activating the β-catenin pathway. Ann Rheum Dis. 2018 Jun; 77(6):935-943. (IF: 19.103)

5. Zou W#, Lai M #, Zhang Y, Zheng L, Xing Z, Li T, Zou Z, Song Q, Zhao X, Xia L, Yang J, Liu A, Zhang H, Cui Z*, Jiang Y*, Bai X*. Exosome Release Is Regulated by mTORC1. Adv Sci, 2018 Dec 11;6(3): 1801313. (IF: 16.806)

6. Jiang Z#, Song Q#, Zeng R#, Li J, Li J, Lin X, Chen X, Zhang J, Zheng Y*，MicroRNA-218 inhibits EMT, migration and invasion by targeting SFMBT1 and DCUN1D1 in cervical cancer, Oncotarget, 2016 Jul 19;7(29):45622-45636. 被引用48次

7. Lai P#, Song Q, Yang C, Li Z, Liu S, Liu B, Li M, Deng H, Cai D, Jin D, Liu A*, Bai X*, Loss of Rictor with aging in osteoblasts promotes age-related bone loss, Cell Death Dis, 2016 Oct 13;7(10):e2408. (IF: 8.469)

8. Jiang Z#, Song Q#, Yang S#, Zeng R, Li X, Jiang C, Ding W, Zhang J, Zheng Y*. Serum microRNA-218 is a potential biomarker for esophageal cancer. Cancer biomarkers, 2015;15(4):381-9. (IF: 4.388)

9. Zou Z#, Chen J#, Liu A, Zhou X, Song Q, Jia C, Chen Z, Lin J, Yang C, Li M, Jiang Y, Bai X*, mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1, J Cell Bio, 2015 Oct 12;211(1):105-22. (IF: 10.539)

10. Chen Z, Dong H, Jia C, Song Q, Chen J, Zhang Y, Lai P, Fan X, Zhou X, Liu M, Lin J, Yang C, Li M, Gao T, Bai X*, Activation of mTORC1 in collecting ducts causes hyperkalemia, J Am Soc Nephrolo, 2014 Mar;25(3):534-45. (IF: 10.121)

学术任职

国际华人骨研学会（ICMRS）会员；中国生理学会会员；广东省细胞生物学学会理事

Signal Transduction and Targeted Therapy、Cell Death and Differentiation等国际学术期刊审稿人

常年招募基础医学院或一临本科生，欢迎对骨生物学、神经生物学感兴趣的年轻人加入到课题组。