导师姓名： 崔忠凯

技术职称： 教授（三级岗） 博士生导师

办 公 室： 生命科学楼15A30

办公电话： 020-61648398

邮 箱： zhongkaicui@smu.edu.cn

个人简介

2018年3月南方医科大学高层次引进人才，广东省级人才项目入选者。回国前就职于美国加州大学洛杉矶分校 (UCLA)，加拿大蒙特利尔大学博士，本科毕业于天津大学。在Nature Communications、Advanced Science、Journal of Controlled Release、ACS Nano等期刊发表SCI论文75篇，其中以第一作者或通讯作者发表37篇，h-index 30，申请国家发明专利5项，授权3项。

研究方向：(1)无细胞疗法促进组织再生修复

(2)细胞信号转导，干细胞增殖与分化

(3)骨关节炎的机制与治疗

(4)自治疗型药物递送系统

执教课程（课程及教材建设）

本科生：《医学细胞生物学》、《动物细胞培养技术》、《Medical Cell Biology》

研究生：《细胞生物学》、《动物细胞培养技术》

国家卫生健康委员会“十三五”规划教材，全国高等学校临床医学专业应用型创新规划教材《基础化学》编委

学术任职

国际华人骨研学会 终身会员

中国细胞生物学学会 终身会员

中国生物材料学会 高级会员

Journal of Orthopaedic Translation 青年编委

2023、2021中国生物材料大会 分会场主持人

2015国际组织工程与再生医学学会(TERMIS) 非病毒基因载体分会联合主席

奖励

代表性论文/著作（包括教学、科研）：

1.Shuxi Ye^#, Jing Wen^#, Wen-Hao Ye, Zhen Li, Xiaomeng Huang, Sixu Chen, Jian-Chao Ma, Yaohong Wu, Rongchun Chen*, Zhong-Kai Cui*, A facile and smart strategy to enhance bone regeneration with efficient vitamin D3 delivery through sterosome technology. Journal of Controlled Release, 2024, 370, 140-151.(IF 10.5，小类1区top)

2. Jian-Chao Ma, Tingting Luo, Binyang Feng, Zicheng Huang, Yiqing Zhang, Hanqing Huang, Xiao Yang, Jing Wen, Xiaochun Bai*, Zhong-Kai Cui*, Exploring the Translational Potential of PLGA Nanoparticles for Intra-articular Rapamycin Delivery in Osteoarthritis Therapy. Journal of Nanobiotechnology, 2023, 21, 361.(IF 10.6，小类1区top)

3. Yiqing Zhang, Jie Zhou, Jiao-Lan Wu, Jian-Chao Ma, Hui Wang, Jing Wen, Shen Huang, Min Lee, Xiaochun Bai, Zhong-Kai Cui*, Intrinsic antibacterial and osteoinductive sterosomes promote infected bone healing. Journal of Controlled Release, 2023, 354, 713-725.(IF 10.5，小类1区top)

4. Zhong-Kai Cui^#,*, Soyon Kim^#, Jessalyn J. Baljon, Benjamin M. Wu, Tara Aghaloo, Min Lee*, Microporous methacrylated glycol chitosan-montmorillonite nanocomposite hydrogel for bone tissue engineering. Nature Communications, 2019, 10, 3523.(IF 14.7，小类1区top，ESI高被引论文)

5. Yu Chen^#, Sheng Zhang^#, Tianjiao Cheng^#, Wei Lin, Linlin Mao, Zhonghui Chen, Yang Yang, Hanqing Huang, Jinqiu Lia*, Zhiyong Ke*, Zhong-Kai Cui*, Design and development of a mitochondrial-targeted photosensitizer for two-photon fluorescence imaging and photodynamic therapy. Journal of Materials Science & Technology, 2023, 141, 135-148.(IF 11.2，小类1区top)

6. Wenchong Zou^#, Mingqiang Lai^#, Yuanjun Jiang^#, Linlin Mao, Wu Zhou, Sheng Zhang, Pinglin Lai, Bin Guo, Tiantian Wei, Chengtao Nie, Lei Zheng, Jiahuan Zhang, Xuefei Gao, Xiaoyang Zhao, Laixin Xia, Zhipeng Zou, Anling Liu, Shiming Liu, Zhong-Kai Cui*, Xiaochun Bai*, Exosome release delays senescence by disposing of obsolete biomolecules. Advanced Science, 2023, 10, 2204826.(IF 14.3，小类1区top)

7. Wenchong Zou^#, Mingqiang Lai^#, Yue Zhang, Lei Zheng, Zhe Xing, Ting Li, Zhipeng Zou, Qiancheng Song, Xiaoyang Zhao, Laixin Xia, Jian Yang, Anling Liu, Han Zhang, Zhong-Kai Cui*, Yu Jiang*, Xiaochun Bai*, Exosome release is regulated by mTORC1. Advanced Science, 2019, 6, 1801313.(IF 14.3，小类1区top)

8. Tingting Cao^#, Huan Chen^#, Weiping Huang^#, Sisi Xu, Peilin Liu, Weiwei Zou, Mao Pang, Ying Xu, Xiaochun Bai, Bin Liu, Limin Rong, Zhong-Kai Cui*, Mangmang Li*, hUC-MSC-mediated recovery of subacute spinal cord injury through enhancing the pivotal subunits β3 and γ2 of the GABA_A receptor. Theranostics, 2022, 12, 3057-3078.(IF 12.4，小类1区top)

9. Kai-Feng Chen^#, Yiqing Zhang^#, Jiawei Lin^#, Jun-You Chen, Caihong Lin, Meng Gao, Yunhua Chen, Sa Liu, Lin Wang*, Zhong-Kai Cui*, Yong-Guang Jia*, Upper Critical Solution Temperature Polyvalent Scaffolds Aggregate and Exterminate Bacteria, Small, 2022, 18, 2107374.(IF 13.0, Frontispiece，小类1区top)

10. Zhong-Kai Cui, Jessalyn J. Baljon, Soyon Kim, Mahmoudreza Doroudgar, Michel Lafleur, Benjamin M. Wu, Tara Aghaloo, Min Lee*, Design and characterization of a therapeutic non-phospholipid liposomal nanocarrier with osteoinductive characteristics to promote bone formation. ACS Nano, 2017, 11, 8055-8063.(IF 15.8，小类1区top)

主持课题（包括教学、科研）：

授权专利

1. 以非磷脂类脂质体作为载体的纳米农药剂型的制备方法及其应用；崔忠凯，杨青，杨君，张正，黄志勇；2021-08

2.一种调控外泌体释放的方法及其医药用途；白晓春，崔忠凯，邹文翀，赖明强，张月；2021-08

3.甾醇脂质体作为牙髓和牙本质药物传递系统的应用；侯晋，崔忠凯，杨小军，詹朝宁，田鑫；2023-09