胡彦锋
科室主任/主任医师
博士生导师
第一临床医学院外科学教研室
电子邮件:yfenghu@qq.com
个人简介
1) 2023年,人民好医生(胃癌领域优秀典范,人民网)
2) 2023年,第三届全国高校教师教学创新大赛 全国三等奖
3) 2023年,广东省高校教师教学创新大赛 特等奖
4) 2022年,广东省医学科技一等奖
5) 2021年,教育部青年长江学者
6) 2019年,广东省科技进步奖一等奖(前三参与人)
7) 2019年,中华医学科技奖一等奖(前三参与人)
8) 2019年,广东省青年五四奖章
9) 2018年,广东省杰出青年医学人才
10) 2017年,广东省自然科学基金杰出青年
11)2017年,广东省特支计划科技创新青年拔尖人才
12)2016年,广东省卫计委、团省委“青年岗位能手”
研究方向
胃癌微创外科诊疗、分子可视化研究、术后综合治疗
代表性论著
1.Morbidity and mortality of laparoscopic versus open D2 distal gastrectomy for advanced gastric cancer: a randomized controlled trial. Hu Y#, Huang C#, Sun Y#, Su X#, Cao H, Hu J, Xue Y, Suo J, Tao K, He X, Wei H, Ying M, Hu W, Du X, Chen P, Liu H, Zheng C, Liu F, YuJ, Li Z, Zhao G, Chen X, Wang K, Li P, Xing J, Li G*. J Clin Oncol. 2016; 34 (12):1350-1357(SCI收录,影响因子:44.544)
2.Vitamin B(12) deficiency after gastrectomy for gastric cancer: an analysis of clinical patterns and risk factors. Hu Y#, Kim HI, Hyung WJ*, Song KJ, Lee JH, Kim YM, Noh SH. Ann Surg. 2013; 258(6):970-975.(SCI 收录,影响因子:12.969)
3.Targeted magnetic resonance imaging/near-infrared Dual-Modal Imaging and Ferroptosis/Starvation Therapy of Gastric Cancer with Peritoneal Metastasis. Weihong Guo#, Yingxin Ren#, Zhian Chen#, Guodong Shen, Yudie Lu, Huimin Zhou, Zhenyuan Li, Zhenhao Li, Xuanyi Lu, Guoxin Li*, Zheyu Shen*, Yanfeng Hu*. Advanced Functional Materials. (SCI收录,影响因子:19.924)
4.Cancer Immunotherapy based on Cell Membrane-coated Nanocomposites Augmenting cGAS/STING activation by Efferocytosis Blockade. Zhian Chen#, Zhenhao Li#, Huilin Huang, Guodong Shen, Yingxin Ren, Xinyuan Mao, Lingzhi Wang, Zhenyuan Li, Weisheng Wang, Guoxin Li*, Bingxia Zhao*, Weihong Guo*, Yanfeng Hu*. Small 2023. ( 通讯作者,中科院2区,SCI收录,影响因子:13.3)
5.Cancer Cell Membrane Biomimetic Mesoporous Silica Nanotheranostics for Enhanced Ferroptosis-mediated Immuogenic Cell Death on Gastric Cancer. Weihong Guo#*, Zhian Chen#, Zhenhao Li#, Huilin Huang, Yingxin Ren, Bingxia Zhao*, Guoxin Li*, Yanfeng Hu*. CHEMICAL ENGINEERING JOURNAL. (SCI收录,影响因子:16.744)
6.Improved Immunotherapy for Gastric Cancer by Nanocomposites with Capability of Triggering Dual-Damage of Nuclear/Mitochondrial DNA and cGAS/STING-Mediated Innate Immunity. Weihong Guo#*, Zhian Chen#, Zhenhao Li, Huilin Huang, Yingxin Ren, Bingxia Zhao*, Guoxin Li*, Yanfeng Hu*. CHEMICAL ENGINEERING JOURNAL. (SCI收录,影响因子:16.744)
7.VB12-Sericin-PBLG-IR780 Nanomicelles for Programming Cell Pyroptosis via Photothermal (PTT)/Photodynamic (PDT) Effect-Induced Mitochondrial DNA (mitoDNA) Oxidative Damage. Weihong Guo#*, Zhenhao Li #, Huilin Huang#, Zhijun Xu#, Zhian Chen, Guodong Shen, Zhenyuan Li, Yingxin Ren, Guoxin Li*, Yanfeng Hu*. ACS Appl Mater Interfaces. 2022 Apr 08. (SCI收录,影响因子:9.229)
8.Graphene oxide (GO)-based nanosheets with combined chemo/photothermal/photodynamic therapy to overcome gastric cancer (GC) paclitaxel resistance by reducing mitochondria-derived adenosine-triphosphate (ATP). Guo W#, Chen Z#, Feng X#, Shen G, Huang H, Liang Y, Zhao B*, Li G*, Hu Y*. J Nanobiotechnology, 2021 May 19;19(1):146.(SCI收录,影响因子:10.435)
9.Biodegradable hollow mesoporous organosilica nanotheranostics (HMON) for multi-mode imaging and mild photo-therapeutic-induced mitochondrial damage on gastric cancer. Guo W#, Chen Z#, Chen J#, Feng X#, Yang Y, Huang H, Liang Y, Shen G, Liang Y, Peng C, Li Y, Li G, Huang W*, Zhao B*, Hu Y*. J Nanobiotechnology 2020; 18(1): 99.(SCI收录,影响因子:10.435)
10.The effects of traditional Chinese medicine and dietary compounds on digestive cancer immunotherapy and gut microbiota modulation: A review. Xiaoli Feng†, Zhenhao Li †, Weihong Guo* and Yanfeng Hu*. Front Immunol 2023.(通讯作者,中科院2区,SCI收录,影响因子:8.87)
11.Safety and short-term outcomes of laparoscopic surgery for advanced gastric cancer after neoadjuvant immunotherapy: A retrospective cohort study. Su J#, Weihong Guo#, Chen Z#, Wang L, Liu H, hao L, Lin T, Li F, Mao X, Huang H, Yu J, Li G, Hu Y*. Front Immunol 2022;13(通讯作者,中科院2区,SCI收录,影响因子:8.87)
12.Yanrui Liang#, Weihong Guo#, Chuangji Li#, Guodong Shen#, Haoxian Tan, Peiwen Sun, Zhian Chen, Huilin Huang, Zhenhao Li, Zhenyuan Li, Yingxin Ren, Guoxin Li*, Yanfeng Hu*. Tumor-Targeted Polydopamine-Based Nanoparticles for Multimodal Mapping Following Photothermal Therapy of Metastatic Lymph Nodes. Int J Nanomedicine. 2022, 17:m4659-4675. (SCI收录,中科院二区,IF2022=8.0)
13.Vitamin-B12-conjugated PLGA-PEG nanoparticles incorporating miR-532-3p induce mitochondrial damage by targeting apoptosis repressor with caspase recruitment domain (ARC) on CD320-overexpressed gastric cancer. Chen Z#, Liang Y#, Feng X#, Liang Y, Shen G, Huang H, Chen Z, Yu J, Liu H, Lin T, Chen H, Wu D, Li G, Zhao B*, Guo W*, Hu Y*. Mater Sci Eng C Mater Biol Appl 2021; 120: 111722.(SCI收录,影响因子:7.328)
代表性课题
1) 国家自然科学基金面上项目2023.01-2026.12, 52万元, 在研, 主持
2) 国家自然科学基金面上项目2020.01-2023.12,55万元,在研,主持;
3) 广东省基础与应用基础研究基金企业联合项目,2022.11-2025.10,15万元,在研,主持;
4) 2023年度农业和社会发展科技专题医疗卫生关键技术研究及应用,2023.04-2026.03,50万元,在研,主持;
5) 南方医科大学南方医院临床研究专项2023.01-2027.12,50万元,在研,主持。