姓名:刘孟华
职称:副教授,硕士生导师
联系邮箱:liumenghua@smu.edu.cn
联系电话:020-61648597
主要招生方向:药剂学、工业药学
学习经历:
2007.09-2010.06 中山大学,植物学,博士
2005.09-2007.06 青海师范大学,植物化学,硕士
1995.09-1999.06 河北大学,生物科学
工作经历:
2013.09-至今 南方医科大学药学院,讲师、副教授
2010.09-2013.06 中山大学,博士后
承担课程:
1. 本科生课程:《生物药剂学与药物动力学》、《药用植物学与生药学》
2. 研究生课程:《分子生物药剂学》、《制剂设计学》、《新药研发技术与方法》
研究方向:
1. 药物非临床药代动力学研究
2. 中药生物活性物质研究
近年主持科研项目:
1.国家自然科学基金-面上项目,No. 82374138,2024.01=2027.12
2.广东省自然科学基金-面上项目,No.2023A1515011814,2023.01=2025.12
3.广东省自然科学基金-面上项目,No.2021A1515011604,2021.01=2023.12
4.国家卫健委出生缺陷研究与预防重点实验室开放课题,No.KF2019002,2019.01=2020.12
5.广东省海洋药物重点实验室开放课题,No.LMM2018-5,2018.1=2019.12
7.国家自然科学基金-青年项目,No.81503376,2016.01=2018.12
近五年代表作:
1. Gao Y#, Ma K#, Zhu Z, Zhang Y, Zhou Q, Wang J, Guo X, Luo L, Wang H, Peng K*, Liu M*. Modified Erchen decoction ameliorates cognitive dysfunction in vascular dementia rats via inhibiting JAK2/STAT3 and JNK/BAX signaling pathways. Phytomedicine. 2023,114: 154797.
2. Ye L#*, Fan S#*, Zhao P#, Wu C#, Liu M#, Hu S#, Wang P#, Wang H, Bi H*. Potential herb‒drug interactions between anti-COVID-19 drugs and traditional Chinese medicine. Acta Pharm Sin B. 2023,5: 1-19.
3. Zou W#, Dong Y#, Yang S, Gong L, Zhang Y, Shi B, La L, Tang L*, Liu M*. Imperatae rhizoma-Hedyotis diffusa Willd. herbal pair alleviates nephrotic syndrome by integrating anti-inflammatory and hypolipidaemic effects. Phytomedicine. 2021,90: 153644.
4. Zou W, Gong L, Zhou F, Long Y, Li Z, Xiao Z, Ouyang B, Liu M*. Anti-inflammatory effect of traditional Chinese medicine preparation Penyanling on pelvic inflammatory disease. J Ethnopharmacol. 2021, 266: 113405.
5. Zou W, Shi B, Zeng T, Zhang Y, Huang B, Ouyang B, Cai Z*, Liu M*. Drug Transporters in the Kidney: Perspectives on Species Differences, Disease Status, and Molecular Docking. Front Pharmacol. 2021,12: 746208.
6. Gong L#, Zou W#, Zheng K, Shi B, Liu M*. The Herba Patriniae (Caprifoliaceae): A review on traditional uses, phytochemistry, pharmacology and quality control. J Ethnopharmacol. 2021,30,265: 113264.
7. Lu X#, Zou W#*, Dong Y, Zhou D, Tong X, Dong Z, Liang G, Tang L, Liu M*. Anti-renal fibrosis effect of asperulosidic acid via TGF-β1/smad2/smad3 and NF-κB signaling pathways in a rat model of unilateral ureteral obstruction. Phytomedicine. 2019,53: 274-285.
8. He J, Dong Y, Liu X, Wan Y, Gu T, Zhou X*, Liu M*. Comparison of Chemical Compositions, Antioxidant, and Anti-Photoaging Activities of Paeonia suffruticosa Flowers at Different Flowering Stages. Antioxidants (Basel). 2019,8: 345.
9. He J, Lu X, Wei T, Dong Y, Cai Z, Tang L, Liu M*. Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages. Int J Mol Sci. 2018,12;19: 2027.
10. Lu X, Zhou F*, Dong Y, Gong L, Li Q, Tang L, Cai Z, He J, Liu M*. Codonopsis tangshen Oliv. Amelioration Effect on Diabetic Kidney Disease Rats Induced by High Fat Diet Feeding Combined with Streptozotocin. Nat Prod Bioprospect. 2018,8(6): 441-451.
授权专利:
1. 刘孟华, 何敬愉, 董雅倩, 唐斓, 刘叔文. 党参炔苷在制备降脂药物中的应用,专利号:201910052096.9
2. 刘孟华, 卢宪媛, 唐斓, 刘叔文. 车叶草苷酸在制备治疗肾纤维化药物中的应用,专利号: 201710477449.0
3. 刘孟华 唐斓 刘叔文 何敬愉. 白花蛇舌草总环戊烯环烯醚萜苷在制备防治急性肾损伤药物中的应用,专利号:201710006702.4