伊峰博士

教授，博士生导师

电子邮件：feng.yi.2020@outlook.com

通讯地址：广东省广州市白云区沙太南路1023号南方医科大学基础医学院（510515）

个人简历

南方医科大学2021年高层次引进人才。博士毕业于复旦大学神经生物学研究所，之后美国蒙大拿大学开展了不同层面的科研训练。期间在Neuron, Journal of Physiology, Neuropharmacology等多个领域核心期刊上发表论文；两篇论文入选F1000Prime；并参与撰写了《NMDA Receptors in the Central Nervous System》和《Selective Cell-Surface Expression of Triheteromeric NMDA Receptors》英文书本章节。

研究方向

1. 谷氨酸受体结构与功能的研究

2. 谷氨酸受体调控手段的开发

3. 谷氨酸受体及其突变参与脑功能和脑疾病的研究

研究关键词

离子通道型谷氨酸受体，结构与功能，神经药理学，脑功能与脑疾病

Inotropic glutamate receptor, Structure and function, Neuropharmacology, Brain functions and disorders

代表性论著

1. Yi F#, Mou TC#, Dorsett KN, Volkmann RA, Menniti FS, Sprang SR, Hansen KB* .Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron 2016, 91(6):1316-1329

Featured by Hiro Furukawa from Cold Spring Harbor Laboratory (preview)

Recommended by Dr. Stephen Traynelis in F1000Prime

2. Hansen KB, Yi F, Perszyk RE, Furukawa H, Wollmuth LP, Gibb AJ, Traynelis SF* . Structure, function, and allosteric modulation of NMDA receptors. The Journal of general physiology 2018, 150(8):1081-1105

Recommended by Dr. Robert Peoples in F1000Prime

3. Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF* Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron 2018 99:315-328 e315. 

4. Yi F#, Rouzbeh N, Hansen KB, Xu Y, Fanger CM, Gordon E, Paschetto K, Menniti FS*, Volkmann RA .PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits. Neuropharmacology 2020 173:107971.(影响因子4.349，JCR2区)

5. Yi F#, Bhattacharya S, Thompson CM, Traynelis SF, Hansen KB*. Functional and pharmacological properties of triheteromeric GluN1/2B/2D NMDA receptors. The Journal of physiology 2019 597:5495-5514.

6. Yi F#, Zachariassen LG, Dorsett KN, Hansen KB* . Properties of Triheteromeric N-Methyl-d-Aspartate Receptors Containing Two Distinct GluN1 Isoforms. Molecular pharmacology 2018 93:453-467.

研究课题与基金

南方医科大学高层次人才引进启动基金，2021-5至2024-4，主持

奖励荣誉

2021南方医科大学高层次引进人才

2014 Early Investigator Prize (Winner), the Journal of Physiology.

招生招聘计划

课题组每年招收硕士和博士研究生各1-2名，长期招收具有细胞生物学、分子遗传学或神经电生理学背景的博士后，有意者请发送邮件咨询。