林骏博士
副教授
电子邮件: linjun_smu@126.com
电话:020-61648207
通讯地址:广东省广州市白云区沙太南路1023号(510515)
研究方向
肿瘤细胞信号转导;乳腺发育。
研究关键词
肿瘤;雷帕霉素靶蛋白;乳腺发育
Tumor;mammalian target or rapamycin; mammary gland development
代表性论著
1. Qin,Zhenqi, Zheng,Hang, Zhou,Ling, Ou,Yanhua, Huang,Bin, Yan,Bo, Qin,Zhenshu, Yang,Cuilan, Su,Yongchun, Bai,Xiaochun*, Guo,Jiasong*, Lin,Jun*.Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins. Sci Rep. 2016; 6: 19587.
2. Zhang, Yue#,Xu, Song#,Lin, Jun#,Yao, Guangyu,Han, Zelong,Liang, Bo,Zou, Zhenhong,Chen, Zhenguo,Song, Qiancheng,Dai, Yifan,Gao, Tianming,Liu, Anling,Bai, Xiaochun*,mTORC1 is a target of nordihydroguaiaretic acid toprevent breast tumor growth in vitro and in vivo. Breast Cancer Research andTreatment. 2012; 136(2):379-388.
3. Li, Haiyan#,Lin, Jun#,Wang, Xiaokai#,Yao, Guangyu,Wang, Liping,Zheng,Hang,Yang, Cuilan,Jia, Chunhong,Liu, Anling(*),Bai, Xiaochun*,Targeting ofmTORC2 prevents cell migration and promotes apoptosis in breast cancer. BreastCancer Research and Treatment. 2012; 134(3):1057-1066.
4. Lin,Jun, Zhang,Xingmei, Yang,Jincheng, Ye Yongbin, Luo,shenqiu*.γ-secretase inhibitor-I enhances radiosensitivity of glioblastoma cell lines by depleting CD133+ tumor cells.Arch Med Res. 2010;41(7):519-29.
代表性课题
青年基金项目,2014-01至2016-12,已结题,主持
执教课程(课程及教材建设)
医学细胞生物学、动物细胞培养技术